Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   SPH_RS11765 Genome accession   NC_010380
Coordinates   2214438..2215100 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae Hungary19A-6     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2209438..2220100
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPH_RS11740 (SPH_2400) - 2209588..2209854 (-) 267 WP_001278167.1 Veg family protein -
  SPH_RS11745 (SPH_2401) dnaB 2209856..2211208 (-) 1353 WP_000852486.1 replicative DNA helicase -
  SPH_RS11750 (SPH_2402) rplI 2211252..2211704 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  SPH_RS11755 (SPH_2403) - 2211701..2213674 (-) 1974 WP_000715124.1 DHH family phosphoesterase -
  SPH_RS11760 (SPH_2404) raiA 2213810..2214358 (-) 549 WP_000599107.1 ribosome-associated translation inhibitor RaiA -
  SPH_RS11765 (SPH_2405) comFC/cflB 2214438..2215100 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  SPH_RS11770 (SPH_2406) comFA/cflA 2215097..2216395 (-) 1299 WP_000867590.1 DEAD/DEAH box helicase Machinery gene
  SPH_RS11775 (SPH_2407) - 2216451..2217086 (+) 636 WP_000395738.1 YigZ family protein -
  SPH_RS11780 (SPH_2408) cysK 2217371..2218297 (+) 927 WP_000029865.1 cysteine synthase A -
  SPH_RS11785 (SPH_2409) tsf 2218418..2219458 (-) 1041 WP_000808062.1 translation elongation factor Ts -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=30055 SPH_RS11765 WP_000649971.1 2214438..2215100(-) (comFC/cflB) [Streptococcus pneumoniae Hungary19A-6]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=30055 SPH_RS11765 WP_000649971.1 2214438..2215100(-) (comFC/cflB) [Streptococcus pneumoniae Hungary19A-6]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914

Multiple sequence alignment