Detailed information NTG0298488

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: DK877_RS05165
• Genome accession: NZ_CP030023
• Coordinates: 1022029..1022868 (+)
• Length: 279 a.a.
• NCBI ID: WP_002936004.1
• Uniprot ID: A0A126UN93
• Organism: Streptococcus suis strain ISU2414
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1022953..1024209	1022029..1022868	flank	85

Gene organization within MGE regions

Location: 1022029..1024209

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK877_RS05165 (DK877_05340)	endA	1022029..1022868 (+)	840	WP_002936004.1	DNA/RNA non-specific endonuclease	Machinery gene
DK877_RS05170 (DK877_05345)	-	1022953..1024209 (-)	1257	WP_053338607.1	ISL3 family transposase	-

Sequence

Protein

• Length: 279 a.a.
• Molecular weight: 30175.36 Da
• Isoelectric Point: 6.2370

>NTDB_id=298488 DK877_RS05165 WP_002936004.1 1022029..1022868(+) (endA) [Streptococcus suis strain ISU2414]
MAKKNVRKQAMSLLSLLATIVVVAGGYLLSDNKSSNVADYSYYVNQSKASEGTPSQELASSVLTEDVKKQLGNSIEWNGA
GAFIINGNQTDLDASVASVPYGDNKTKTVQGETVPTVANALLAKSTRQYKDREETGNGRTSWTPAGWHQIHDLTGEYDHA
VDRGHLLGYALIGGLSGFDASTSNPKNIAVQTAWSNQANDQTSTGQNYFESQIRRALDKNKRIRYRVTLVYAESEDLVPV
GSHLEAKAADGSLEFNVFVPNVQSGLSINYHSGEIAVNQ

Nucleotide

• Length: 840 bp

>NTDB_id=298488 DK877_RS05165 WP_002936004.1 1022029..1022868(+) (endA) [Streptococcus suis strain ISU2414]
ATGGCGAAGAAAAATGTAAGAAAACAAGCAATGAGTCTGCTCAGCTTATTGGCTACGATTGTTGTCGTAGCGGGTGGCTA
TCTTTTAAGTGATAACAAGAGCAGTAACGTTGCTGATTATTCCTATTATGTCAATCAGTCTAAGGCAAGTGAAGGCACAC
CTAGTCAGGAACTGGCTAGTTCGGTATTGACAGAAGATGTAAAAAAGCAACTGGGGAATTCGATTGAATGGAATGGCGCT
GGAGCATTTATTATTAACGGTAATCAAACAGATTTAGATGCATCGGTTGCCAGTGTACCTTATGGTGATAATAAGACAAA
GACAGTCCAGGGAGAAACGGTTCCAACAGTAGCCAATGCGCTTTTAGCTAAATCTACACGTCAGTATAAGGATCGTGAAG
AAACAGGAAATGGTCGAACTTCTTGGACACCTGCGGGTTGGCATCAGATCCATGATTTAACTGGAGAATATGACCATGCA
GTGGACCGTGGTCACCTCCTAGGTTATGCTTTGATTGGTGGATTGTCTGGCTTCGATGCTTCAACCAGCAATCCTAAGAA
TATTGCAGTTCAAACAGCTTGGTCCAACCAAGCTAACGACCAAACTTCAACTGGGCAGAATTATTTTGAAAGTCAGATTC
GGCGGGCCTTGGATAAAAATAAGCGTATCCGCTATCGTGTGACCTTGGTGTATGCTGAGAGTGAAGACCTTGTTCCTGTC
GGAAGCCATCTAGAGGCAAAAGCAGCAGATGGTAGCCTAGAGTTCAATGTGTTCGTTCCAAATGTGCAGAGTGGTCTCAG
TATCAACTATCATAGTGGGGAAATTGCAGTAAATCAATAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (81-236)

3D structure

• AlphaFold DB: A0A126UN93

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	69.915	84.588	0.591
endA	Streptococcus pneumoniae D39	69.915	84.588	0.591
endA	Streptococcus pneumoniae R6	69.915	84.588	0.591
endA	Streptococcus pneumoniae TIGR4	69.915	84.588	0.591