Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   DK875_RS05880 Genome accession   NZ_CP030020
Coordinates   1204977..1205816 (-) Length   279 a.a.
NCBI ID   WP_002936004.1    Uniprot ID   A0A126UN93
Organism   Streptococcus suis strain ISU2514     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1199977..1210816
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK875_RS05865 (DK875_06125) uidA 1200340..1202139 (-) 1800 WP_002938035.1 beta-glucuronidase -
  DK875_RS05870 (DK875_06130) - 1202155..1203183 (-) 1029 WP_013730404.1 sugar kinase -
  DK875_RS05875 (DK875_06135) - 1203239..1204790 (-) 1552 Protein_1141 MFS transporter -
  DK875_RS05880 (DK875_06140) endA 1204977..1205816 (-) 840 WP_002936004.1 DNA/RNA non-specific endonuclease Machinery gene
  DK875_RS05885 (DK875_06145) - 1205846..1206037 (-) 192 WP_002936005.1 DNA-directed RNA polymerase subunit beta -
  DK875_RS05890 (DK875_06150) murA 1206030..1207313 (-) 1284 WP_002936006.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  DK875_RS05895 (DK875_06155) - 1207338..1207562 (-) 225 WP_053866410.1 DUF1146 family protein -
  DK875_RS05900 (DK875_06160) - 1207622..1208038 (-) 417 WP_002936007.1 F0F1 ATP synthase subunit epsilon -
  DK875_RS05905 (DK875_06165) atpD 1208048..1209454 (-) 1407 WP_002936008.1 F0F1 ATP synthase subunit beta -
  DK875_RS05910 (DK875_06170) - 1209474..1210352 (-) 879 WP_002936012.1 F0F1 ATP synthase subunit gamma -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30175.36 Da        Isoelectric Point: 6.2370

>NTDB_id=298369 DK875_RS05880 WP_002936004.1 1204977..1205816(-) (endA) [Streptococcus suis strain ISU2514]
MAKKNVRKQAMSLLSLLATIVVVAGGYLLSDNKSSNVADYSYYVNQSKASEGTPSQELASSVLTEDVKKQLGNSIEWNGA
GAFIINGNQTDLDASVASVPYGDNKTKTVQGETVPTVANALLAKSTRQYKDREETGNGRTSWTPAGWHQIHDLTGEYDHA
VDRGHLLGYALIGGLSGFDASTSNPKNIAVQTAWSNQANDQTSTGQNYFESQIRRALDKNKRIRYRVTLVYAESEDLVPV
GSHLEAKAADGSLEFNVFVPNVQSGLSINYHSGEIAVNQ

Nucleotide


Download         Length: 840 bp        

>NTDB_id=298369 DK875_RS05880 WP_002936004.1 1204977..1205816(-) (endA) [Streptococcus suis strain ISU2514]
ATGGCGAAGAAAAATGTAAGAAAACAAGCAATGAGTCTGCTCAGCTTATTGGCTACGATTGTTGTCGTAGCGGGTGGCTA
TCTTTTAAGTGATAACAAGAGCAGTAACGTTGCTGATTATTCCTATTATGTCAATCAGTCTAAGGCAAGTGAAGGCACAC
CTAGTCAGGAACTGGCTAGTTCGGTATTGACAGAAGATGTAAAAAAGCAACTGGGGAATTCGATTGAATGGAATGGCGCT
GGAGCATTTATTATTAACGGTAATCAAACAGATTTAGATGCATCGGTTGCCAGTGTACCTTATGGTGATAATAAGACAAA
GACAGTCCAGGGAGAAACGGTTCCAACAGTAGCCAATGCGCTTTTAGCTAAATCTACACGTCAGTATAAGGATCGTGAAG
AAACAGGAAATGGTCGAACTTCTTGGACACCTGCGGGTTGGCATCAGATCCATGATTTAACTGGAGAATATGACCATGCA
GTGGACCGTGGTCACCTCCTAGGTTATGCTTTGATTGGTGGATTGTCTGGCTTCGATGCTTCAACCAGCAATCCTAAGAA
TATTGCAGTTCAAACAGCTTGGTCCAACCAAGCTAACGACCAAACTTCAACTGGGCAGAATTATTTTGAAAGTCAGATTC
GGCGGGCCTTGGATAAAAATAAGCGTATCCGCTATCGTGTGACCTTGGTGTATGCTGAGAGTGAAGACCTTGTTCCTGTC
GGAAGCCATCTAGAGGCAAAAGCAGCAGATGGTAGCCTAGAGTTCAATGTGTTCGTTCCAAATGTGCAGAGTGGTCTCAG
TATCAACTATCATAGTGGGGAAATTGCAGTAAATCAATAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(81-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A126UN93

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

69.915

84.588

0.591
  endA Streptococcus pneumoniae D39

69.915

84.588

0.591
  endA Streptococcus pneumoniae R6

69.915

84.588

0.591
  endA Streptococcus pneumoniae TIGR4

69.915

84.588

0.591

Multiple sequence alignment