Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   A7J09_RS07420 Genome accession   NZ_CP030015
Coordinates   1525640..1526479 (-) Length   279 a.a.
NCBI ID   WP_029174677.1    Uniprot ID   A0A0M9FKY2
Organism   Streptococcus suis strain ISU2812     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1520640..1531479
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J09_RS07405 (A7J09_07545) uidA 1521000..1522799 (-) 1800 WP_029178397.1 beta-glucuronidase -
  A7J09_RS07410 (A7J09_07550) - 1522815..1523843 (-) 1029 WP_024403160.1 sugar kinase -
  A7J09_RS07415 (A7J09_07555) - 1523900..1525453 (-) 1554 WP_024394170.1 MFS transporter -
  A7J09_RS07420 (A7J09_07560) endA 1525640..1526479 (-) 840 WP_029174677.1 DNA/RNA non-specific endonuclease Machinery gene
  A7J09_RS07425 (A7J09_07565) - 1526509..1526700 (-) 192 WP_012775177.1 DNA-directed RNA polymerase subunit beta -
  A7J09_RS07430 (A7J09_07570) murA 1526693..1527976 (-) 1284 Protein_1436 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  A7J09_RS07435 (A7J09_07575) - 1528001..1528225 (-) 225 WP_012775178.1 DUF1146 family protein -
  A7J09_RS07440 (A7J09_07580) - 1528285..1528701 (-) 417 WP_002936007.1 F0F1 ATP synthase subunit epsilon -
  A7J09_RS07445 (A7J09_07585) atpD 1528711..1530117 (-) 1407 WP_002936008.1 F0F1 ATP synthase subunit beta -
  A7J09_RS07450 (A7J09_07590) - 1530137..1531015 (-) 879 WP_002936012.1 F0F1 ATP synthase subunit gamma -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30159.40 Da        Isoelectric Point: 6.2370

>NTDB_id=298264 A7J09_RS07420 WP_029174677.1 1525640..1526479(-) (endA) [Streptococcus suis strain ISU2812]
MAKKNVKKQAMSLLSLLATIVVVAGGYLLSDNKSSNVADYSYYVNQSKASEGTPSQELASSVLTEDVKKQLGNSIEWNGA
GAFIINGNQTDLDASVASVPYGDNKTKTVQGETVPTVANALLAKSTRQYKDREEIGNGRTSWTPAGWHQIHDLTGEYDHA
VDRGHLLGYALIGGLSGFDASTSNPKNIAVQTAWSNQANDQTSTGQNYFESQIRRALDKNKRVRYRVTLVYAESEDLVPV
GSHLEAKAADGSLEFNVFIPNVQSGLSINYHSGEIAVNQ

Nucleotide


Download         Length: 840 bp        

>NTDB_id=298264 A7J09_RS07420 WP_029174677.1 1525640..1526479(-) (endA) [Streptococcus suis strain ISU2812]
ATGGCGAAGAAAAATGTAAAAAAACAAGCAATGAGTCTGCTCAGCTTATTGGCTACGATTGTTGTAGTAGCGGGTGGCTA
TCTTTTAAGTGATAACAAGAGCAGTAACGTTGCTGATTATTCCTATTATGTCAATCAGTCTAAGGCAAGTGAAGGCACAC
CTAGTCAGGAACTGGCTAGTTCGGTATTGACAGAAGATGTAAAAAAGCAACTGGGGAATTCGATTGAATGGAATGGCGCT
GGAGCATTTATTATTAACGGTAATCAAACGGATTTAGATGCATCGGTTGCCAGTGTTCCTTATGGTGATAATAAGACAAA
AACAGTCCAGGGAGAAACGGTTCCAACGGTAGCCAATGCGCTTTTAGCTAAATCTACACGTCAGTATAAGGACCGTGAAG
AAATAGGAAATGGTCGGACTTCTTGGACACCTGCGGGTTGGCATCAGATCCATGATTTAACTGGAGAATATGACCATGCA
GTGGACCGTGGTCACCTCCTAGGTTATGCTTTGATTGGTGGATTGTCTGGCTTCGATGCTTCAACCAGCAATCCTAAGAA
TATTGCAGTTCAAACAGCTTGGTCCAACCAAGCTAACGACCAAACTTCAACTGGGCAGAATTATTTTGAAAGTCAGATTC
GGCGGGCCTTGGATAAAAATAAGCGTGTCCGCTATCGTGTGACCTTGGTGTATGCTGAGAGTGAAGACCTTGTTCCTGTC
GGAAGCCATCTAGAGGCAAAAGCAGCAGATGGTAGCTTAGAGTTCAATGTGTTCATTCCAAATGTGCAGAGTGGTCTCAG
TATCAATTATCATAGTGGGGAAATTGCAGTAAATCAATAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(81-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FKY2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

69.492

84.588

0.588
  endA Streptococcus pneumoniae D39

69.492

84.588

0.588
  endA Streptococcus pneumoniae R6

69.492

84.588

0.588
  endA Streptococcus pneumoniae TIGR4

69.492

84.588

0.588

Multiple sequence alignment