Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   ESP48_RS04335 Genome accession   NZ_CP035306
Coordinates   816471..816764 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain IDCC2201     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 811471..821764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ESP48_RS04295 (ESP48_04295) - 811872..812315 (-) 444 WP_011681680.1 hypothetical protein -
  ESP48_RS10105 (ESP48_04300) - 812389..812814 (-) 426 WP_014608739.1 CPBP family intramembrane glutamic endopeptidase -
  ESP48_RS10110 (ESP48_04305) - 812771..813046 (-) 276 WP_011681681.1 hypothetical protein -
  ESP48_RS04310 (ESP48_04310) - 813058..813256 (-) 199 Protein_823 helix-turn-helix transcriptional regulator -
  ESP48_RS04315 (ESP48_04315) - 813505..814698 (-) 1194 WP_014608740.1 acetate kinase -
  ESP48_RS04320 (ESP48_04320) comGH 814754..815710 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  ESP48_RS04325 (ESP48_04325) comGG 815755..816072 (-) 318 WP_011681685.1 competence type IV pilus minor pilin ComGG Machinery gene
  ESP48_RS04330 (ESP48_04330) comGF 816050..816487 (-) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  ESP48_RS04335 (ESP48_04335) comGE 816471..816764 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  ESP48_RS04340 (ESP48_04340) comGD 816736..817164 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  ESP48_RS04345 (ESP48_04345) comGC 817124..817450 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  ESP48_RS04350 (ESP48_04350) comGB 817447..818547 (-) 1101 WP_120764773.1 competence type IV pilus assembly protein ComGB Machinery gene
  ESP48_RS04355 (ESP48_04355) comGA/cglA/cilD 818429..819370 (-) 942 WP_014608745.1 competence type IV pilus ATPase ComGA Machinery gene
  ESP48_RS04360 (ESP48_04360) - 819451..819813 (-) 363 WP_014608746.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=298148 ESP48_RS04335 WP_011226625.1 816471..816764(-) (comGE) [Streptococcus thermophilus strain IDCC2201]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=298148 ESP48_RS04335 WP_011226625.1 816471..816764(-) (comGE) [Streptococcus thermophilus strain IDCC2201]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361