Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   SPJ_RS07555 Genome accession   NC_012466
Coordinates   1447898..1448575 (-) Length   225 a.a.
NCBI ID   WP_000548959.1    Uniprot ID   Q9S1K2
Organism   Streptococcus pneumoniae JJA     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1442898..1453575
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPJ_RS07530 (SPJ_1522) - 1443060..1443689 (-) 630 WP_000762099.1 NAD(P)-dependent oxidoreductase -
  SPJ_RS07535 - 1443927..1444127 (+) 201 WP_001814296.1 hypothetical protein -
  SPJ_RS07540 (SPJ_1523) - 1444558..1444881 (+) 324 WP_000422781.1 hypothetical protein -
  SPJ_RS07545 (SPJ_1524) thrS 1444939..1446882 (+) 1944 WP_000608358.1 threonine--tRNA ligase -
  SPJ_RS07550 (SPJ_1525) - 1446931..1447905 (-) 975 WP_000887950.1 HAMP domain-containing histidine kinase -
  SPJ_RS07555 (SPJ_1526) braR 1447898..1448575 (-) 678 WP_000548959.1 response regulator transcription factor Regulator
  SPJ_RS07560 (SPJ_1527) - 1448731..1449804 (+) 1074 WP_001273834.1 DUF2974 domain-containing protein -
  SPJ_RS07565 (SPJ_1528) - 1449895..1450197 (-) 303 WP_000281608.1 hypothetical protein -
  SPJ_RS07570 (SPJ_1529) - 1450265..1450702 (-) 438 WP_001166792.1 Rrf2 family transcriptional regulator -
  SPJ_RS07575 (SPJ_1530) - 1450778..1451620 (-) 843 WP_000160958.1 metallophosphoesterase family protein -
  SPJ_RS07580 (SPJ_1531) - 1451732..1452382 (+) 651 WP_000188497.1 metal-dependent transcriptional regulator -
  SPJ_RS07590 (SPJ_1533) - 1452676..1453227 (+) 552 WP_225532561.1 nicotinamide mononucleotide transporter -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25964.16 Da        Isoelectric Point: 5.1362

>NTDB_id=29793 SPJ_RS07555 WP_000548959.1 1447898..1448575(-) (braR) [Streptococcus pneumoniae JJA]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=29793 SPJ_RS07555 WP_000548959.1 1447898..1448575(-) (braR) [Streptococcus pneumoniae JJA]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTTTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369

Multiple sequence alignment