Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   SUB_RS07650 Genome accession   NC_012004
Coordinates   1515808..1516590 (-) Length   260 a.a.
NCBI ID   WP_015911836.1    Uniprot ID   B9DVH6
Organism   Streptococcus uberis 0140J     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1510808..1521590
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUB_RS07615 (SUB1521) - 1511143..1511772 (-) 630 WP_015911830.1 helix-turn-helix transcriptional regulator -
  SUB_RS07620 (SUB1522) - 1511911..1512249 (+) 339 Protein_1469 3-hydroxyacyl-CoA dehydrogenase family protein -
  SUB_RS07625 (SUB1523) - 1512357..1512653 (-) 297 WP_015911831.1 rhodanese-like domain-containing protein -
  SUB_RS07630 (SUB1524) - 1512646..1514301 (-) 1656 WP_015911832.1 FAD-dependent oxidoreductase -
  SUB_RS07635 (SUB1525) - 1514312..1514650 (-) 339 WP_015911833.1 rhodanese-like domain-containing protein -
  SUB_RS07640 (SUB1526) - 1514789..1515049 (+) 261 WP_015911834.1 metal-sensitive transcriptional regulator -
  SUB_RS07645 (SUB1527) - 1515116..1515667 (-) 552 WP_172455889.1 cysteine hydrolase family protein -
  SUB_RS07650 (SUB1528) codY 1515808..1516590 (-) 783 WP_015911836.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  SUB_RS07655 (SUB1529) - 1516786..1518000 (-) 1215 WP_015911837.1 pyridoxal phosphate-dependent aminotransferase -
  SUB_RS07660 (SUB1530) - 1518195..1518647 (+) 453 WP_015911838.1 universal stress protein -
  SUB_RS07665 (SUB1531) - 1518680..1520068 (-) 1389 WP_015911839.1 Cof-type HAD-IIB family hydrolase -
  SUB_RS07670 (SUB1532) - 1520140..1521102 (+) 963 WP_015911840.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28751.05 Da        Isoelectric Point: 4.7174

>NTDB_id=29704 SUB_RS07650 WP_015911836.1 1515808..1516590(-) (codY) [Streptococcus uberis 0140J]
MPNLLEKTRKITSILQRSVDSLDAELPYNAMASRLADIIDCNACIINGGGTLLGYAMKYKTNNDRVEEFFEAKQFPDSYV
KAASRVYDTEANLPVENELTIFPIESKNTYPDGLTTIAPIYGGGMRLGSLIIWRNDKKFLDEDLILVEISSTVVGIQLLN
LQTENLEETIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFDKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=29704 SUB_RS07650 WP_015911836.1 1515808..1516590(-) (codY) [Streptococcus uberis 0140J]
ATGCCAAATTTATTAGAAAAAACACGTAAAATCACATCTATATTACAGCGTTCCGTAGATAGTTTGGATGCAGAATTGCC
CTATAATGCAATGGCATCTCGCTTAGCTGATATCATTGACTGTAATGCATGTATTATCAATGGTGGCGGTACTCTTTTAG
GTTACGCCATGAAATATAAAACCAATAATGACCGAGTAGAAGAATTTTTTGAAGCAAAGCAATTCCCAGATTCTTACGTT
AAAGCGGCTAGTCGTGTTTATGATACAGAAGCAAACTTGCCTGTAGAAAATGAATTAACCATTTTCCCAATTGAATCAAA
AAATACTTATCCAGATGGTTTAACGACAATTGCTCCAATTTATGGTGGTGGTATGCGTCTGGGGTCTTTAATCATTTGGC
GAAATGACAAAAAATTTCTTGATGAAGATTTGATTTTGGTTGAAATTTCTAGTACCGTTGTGGGTATTCAGTTGTTAAAC
TTGCAAACGGAAAATCTTGAGGAAACCATTCGTAAGCAAACGGCTGTTAATATGGCAATTAATACCTTATCATATTCTGA
AATGAAAGCAGTTGCTGCCATTTTAGGTGAACTTGATGGCAATGAGGGGCGTTTAACGGCGTCAGTCATCGCTGACCGTA
TCGGTATTACACGATCTGTGATCGTCAATGCCCTTCGTAAATTGGAAAGTGCTGGTATTATTGAAAGTCGCTCTCTGGGT
ATGAAGGGAACCTACCTCAAGGTTATTAATGAGGGAATTTTTGATAAATTGAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B9DVH6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.926

98.846

0.662
  codY Bacillus subtilis subsp. subtilis str. 168

52.227

95

0.496

Multiple sequence alignment