Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGH   Type   Machinery gene
Locus tag   EQH31_RS09940 Genome accession   NZ_CP035249
Coordinates   1929499..1930452 (-) Length   317 a.a.
NCBI ID   WP_000345118.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901938     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1924499..1935452
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH31_RS09915 (EQH31_10525) - 1925260..1925883 (-) 624 WP_000932638.1 hypothetical protein -
  EQH31_RS09920 (EQH31_10530) jag 1925934..1926920 (-) 987 WP_000260014.1 RNA-binding cell elongation regulator Jag/EloR -
  EQH31_RS09925 (EQH31_10535) - 1926939..1927763 (-) 825 WP_000727909.1 membrane protein insertase YidC -
  EQH31_RS09930 (EQH31_10540) rnpA 1927738..1928109 (-) 372 WP_000739246.1 ribonuclease P protein component -
  EQH31_RS11085 - 1928126..1928257 (-) 132 WP_000768904.1 hypothetical protein -
  EQH31_RS09935 (EQH31_10545) - 1928258..1929448 (-) 1191 WP_000167769.1 acetate kinase -
  EQH31_RS09940 (EQH31_10550) comGH 1929499..1930452 (-) 954 WP_000345118.1 class I SAM-dependent methyltransferase Machinery gene
  EQH31_RS09945 (EQH31_10555) - 1930798..1931599 (+) 802 WP_128887635.1 IS5 family transposase -
  EQH31_RS09950 (EQH31_10560) - 1931750..1932226 (+) 477 WP_000777686.1 GNAT family N-acetyltransferase -
  EQH31_RS09955 (EQH31_10565) comGG/cglG 1932900..1933292 (-) 393 WP_001818966.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH31_RS09960 (EQH31_10570) comGF/cglF 1933270..1933731 (-) 462 WP_000250537.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH31_RS09965 (EQH31_10575) comGE/cglE 1933694..1933996 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH31_RS09970 (EQH31_10580) comGD/cglD 1933959..1934363 (-) 405 WP_000588017.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH31_RS09975 (EQH31_10585) comGC/cglC 1934356..1934682 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35699.89 Da        Isoelectric Point: 4.2434

>NTDB_id=296512 EQH31_RS09940 WP_000345118.1 1929499..1930452(-) (comGH) [Streptococcus pneumoniae strain TVO_1901938]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLISLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=296512 EQH31_RS09940 WP_000345118.1 1929499..1930452(-) (comGH) [Streptococcus pneumoniae strain TVO_1901938]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGATCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTGGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterProScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGH Streptococcus mutans UA140

54.952

98.738

0.543
  comGH Streptococcus mutans UA159

54.633

98.738

0.539