Detailed information NTG0295205

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CSC58_RS13130
• Genome accession: NZ_CP029681
• Coordinates: 2522803..2523690 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain AR_0473
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2517803..2528690

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSC58_RS13100 (CSC58_2431)	-	2518535..2519296 (+)	762	WP_000323447.1	alpha/beta hydrolase family protein	-
CSC58_RS13105 (CSC58_2432)	-	2519541..2519996 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
CSC58_RS15005	-	2520118..2520219 (+)	102	WP_000731972.1	SE2200 family small protein	-
CSC58_RS13115 (CSC58_2433)	-	2520279..2521703 (-)	1425	WP_000953762.1	alkaline phosphatase	-
CSC58_RS13120 (CSC58_2434)	-	2521901..2522101 (+)	201	WP_000604727.1	hypothetical protein	-
CSC58_RS13125 (CSC58_2435)	braR	2522127..2522792 (+)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CSC58_RS13130 (CSC58_2436)	braS	2522803..2523690 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CSC58_RS13135 (CSC58_2437)	-	2523799..2524554 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
CSC58_RS13140 (CSC58_2438)	-	2524551..2526551 (+)	2001	WP_000776739.1	ABC transporter permease	-
CSC58_RS13145	-	2527210..2527323 (+)	114	Protein_2451	hypothetical protein	-
CSC58_RS13155	-	2527705..2527965 (+)	261	WP_001789910.1	hypothetical protein	-
CSC58_RS13160 (CSC58_2439)	-	2527975..2528472 (+)	498	WP_001065269.1	glutathione peroxidase	-
CSC58_RS13165	-	2528580..2528672 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=295205 CSC58_RS13130 WP_000143420.1 2522803..2523690(+) (braS) [Staphylococcus aureus strain AR_0473]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=295205 CSC58_RS13130 WP_000143420.1 2522803..2523690(+) (braS) [Staphylococcus aureus strain AR_0473]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993