Detailed information    

insolico Bioinformatically predicted

Overview

Name   recD/recD2/recDB   Type   Machinery gene
Locus tag   EQH43_RS02175 Genome accession   NZ_CP035237
Coordinates   404925..407291 (-) Length   788 a.a.
NCBI ID   WP_000454509.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_Taiwan19F-14     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 399925..412291
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH43_RS02150 (EQH43_02260) vraR 400276..400908 (+) 633 WP_000698433.1 response regulator transcription factor Regulator
  EQH43_RS10820 (EQH43_02265) - 400909..401151 (+) 243 Protein_429 DNA alkylation repair protein -
  EQH43_RS02155 - 401076..401678 (+) 603 Protein_430 DNA alkylation repair protein -
  EQH43_RS02160 (EQH43_02280) - 402137..402739 (+) 603 Protein_431 trypsin-like serine peptidase -
  EQH43_RS02165 (EQH43_02285) - 403095..403400 (+) 306 WP_001821501.1 tyrosine-type recombinase/integrase -
  EQH43_RS02170 (EQH43_02290) tig 403594..404877 (+) 1284 WP_000116462.1 trigger factor -
  EQH43_RS02175 (EQH43_02295) recD/recD2/recDB 404925..407291 (-) 2367 WP_000454509.1 ATP-dependent RecD-like DNA helicase Machinery gene
  EQH43_RS02180 (EQH43_02300) lepB 407419..408033 (-) 615 WP_001083986.1 signal peptidase I -
  EQH43_RS02185 (EQH43_02305) rnhC 408037..408918 (-) 882 WP_000146863.1 ribonuclease HIII -
  EQH43_RS02190 (EQH43_02310) zapA 409005..409307 (+) 303 WP_000002019.1 cell division protein ZapA -
  EQH43_RS02195 (EQH43_02315) - 409304..409852 (+) 549 WP_000622953.1 CvpA family protein -

Sequence

Protein


Download         Length: 788 a.a.        Molecular weight: 88592.46 Da        Isoelectric Point: 4.5885

>NTDB_id=295131 EQH43_RS02175 WP_000454509.1 404925..407291(-) (recD/recD2/recDB) [Streptococcus pneumoniae strain TVO_Taiwan19F-14]
MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVTGTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRA
KPTSKGLVKYFSSSHFKGIGLKTAQKIVDTYGENTIDEILQHPEKLEGIVGLSAKNREAFVSTLRLNYGTEMILAKLANY
GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERFRAGLVHSLFQACMETGDTYVEV
RDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDKVQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKH
ITTIEEELGIEYDNIQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPTGRAARRMN
ELTGLPSATIHRHLGMTGDDDTSHLEDYLDTDFIIVDEFSMVDTWLANQLFSNISSNSKILIVGDSDQLPSVSPGQVLAD
LLHIPLIPQTRLEKIYRQSEESTIVTLASQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQV
LAPMYRGTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDTEINVFNGDLGAITDLIPGKYTESKQDEI
VIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPITSASRRMLERNLIYTAITRAKSKLILLGELQAFDHATQ
HIGTARKTYLVERFSDLLKNVEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK

Nucleotide


Download         Length: 2367 bp        

>NTDB_id=295131 EQH43_RS02175 WP_000454509.1 404925..407291(-) (recD/recD2/recDB) [Streptococcus pneumoniae strain TVO_Taiwan19F-14]
ATGGAAGTTTATTTTTCAGGAACTATTGAACGGATTATTTTTGAAAATCCCAGCAATTTTTATCGCATCCTCCTCCTAGA
AATCGACGATACGGACGCAGAGGATTTTGATGATTTTGAAATCATTGTCACAGGAACCATGGCTGATGTAATTGAGGGCG
AAGACTATACTTTTTGGGGGCAAATTGTCCAGCACTCCAAGTATGGAGAACAACTGCAAATCAGTCGTTATGATCGCGCA
AAACCAACTAGTAAGGGCTTGGTCAAGTACTTTTCAAGTAGCCATTTCAAGGGGATTGGTCTCAAGACAGCTCAGAAAAT
CGTGGATACCTATGGCGAAAATACCATTGACGAAATTTTGCAACACCCAGAAAAGTTAGAAGGCATCGTAGGACTCTCTG
CCAAAAATCGCGAGGCTTTCGTCTCCACTCTCCGTCTCAACTACGGAACGGAGATGATTTTGGCCAAACTAGCCAACTAC
GGCATTCCCAACAAACTAGCCTTTCAGATTCAAGACTTTTACAAGGAAGAAACCCTTGATGTGGTTGAAAATTATCCCTA
CCAGCTGGTTGAGGATATCAAGGGTTTGGGCTTTACCATTGCTGACCAACTAGCTGAGGAACTAGGCATCGAAAGTCAGG
CTCCTGAACGCTTCCGCGCCGGTCTAGTTCACAGTCTTTTTCAGGCCTGTATGGAAACAGGGGACACCTATGTTGAAGTA
CGGGATTTGCTGGAACAAACCCTTACTCTCCTTGAGTCTTCCCGTCCCGTGGAACTAGACCCCAGCCAAGTTGCCCAAGA
GCTCTCCTACCTGATCGAAGAAGACAAGGTTCAGCAGATTGATACCAAGATCTTTGACAACAGCCTCTTTTTCGCTGAGG
AAGGCATCCGCAGTCACTTGGTTCGTATCCTTGAAAAAGGAAAACAGAAGAGTCATGATTTAGAAACCATTCAAAAACAT
ATCACTACTATCGAGGAAGAGCTGGGAATTGAGTATGATAACATTCAAAAACAGGCTATCTGTGATGCTATCCAGAATAA
GGTCTTTATCCTGACAGGTGGACCTGGTACTGGTAAGACAACTGTTATCAATGGGATCATCGCTGTTTACGCCCTGTTAG
AGGGACTTGACCTCAGGAAGAAAAGCAACCTGCCCATTCTTCTTGCTGCTCCAACTGGACGAGCCGCTCGTCGCATGAAT
GAATTGACAGGCTTGCCTAGCGCGACCATACACCGCCACTTGGGAATGACAGGTGACGATGATACCAGTCATCTGGAAGA
TTACCTAGATACTGACTTTATCATCGTGGATGAATTCTCTATGGTGGATACTTGGCTGGCCAATCAACTCTTCTCCAATA
TCTCTTCTAACAGTAAGATCCTCATCGTAGGTGACAGTGATCAGCTACCTTCTGTCAGTCCTGGACAGGTTCTAGCGGAT
CTGCTTCATATTCCTTTGATTCCTCAGACTCGCTTGGAAAAAATTTATCGACAAAGCGAAGAATCAACCATCGTCACCCT
AGCTAGTCAGATTCGACAGGGCATCTTGCCAGCTGATTTCACCCAAAAAAAAGCTGACCGTTCCTACTTTGAAATTGCTA
GTGGCCATATTCCTGCCACCATTGAAAAAATCTTAGGTGCCGCCCTCAGAAATGGTATTCCTGCCCGTGATATCCAAGTT
CTGGCTCCTATGTACCGAGGGACGGCAGGGATTGATGCTATCAATCAGCTCATGCAAGACCTGCTCAATCCCCCACAAAA
AGATCAACTCAGTTTTGAAGCTCCTCAGTGCCACTATCGTAAGGGAGACAAGGTCATTCATTTGGTTAACGATACTGAAA
TCAATGTCTTTAATGGGGATTTAGGAGCTATCACAGACCTGATTCCTGGTAAATACACCGAATCGAAACAAGACGAGATT
GTCATTGATTTTGATGGTAATGAAGTCTCTTACCCCCGTAACGAATGGTACAAGATTCGCTTGGCCTATGCCATGAGTAT
TCATAAGTCTCAGGGAAGTGAGTTCCCAGTTGTCATCCTACCGATTACTAGTGCTAGCCGACGTATGCTGGAGCGAAATC
TCATCTACACAGCCATTACACGTGCCAAAAGCAAACTCATCTTACTAGGCGAATTACAAGCCTTCGACCATGCTACCCAA
CACATCGGAACTGCCCGAAAAACCTATCTGGTTGAACGCTTCAGTGATCTACTGAAGAATGTTGAAGAAAAGCAACAAGC
TGTCTCTGAAACAGTCACATCAAGTGCCTCTGAACAATCCTACATCCTAACCGAAGAAAACTGGGACCGCATCCCAGCCA
TGATTGGGATTACAGACACAGACCTCAAAGAGATTTTTGGAAAATAG

Domains

Predicted by InterProScan.

UvrD-like helicase C-terminal domain (UvrD_C_2)

(662-709)

Helix-hairpin-helix containing domain (HHH_RecD2)

(148-237)

ATP-dependent RecD-like DNA helicase SH3 domain (SH3_13)

(574-644)

AAA domain (AAA_30)

(332-520)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recD/recD2/recDB Bacillus subtilis subsp. subtilis str. 168

41.845

94.924

0.397