Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   SPN23F_RS01960 Genome accession   NC_011900
Coordinates   368686..371022 (+) Length   778 a.a.
NCBI ID   WP_001035036.1    Uniprot ID   B8ZLH4
Organism   Streptococcus pneumoniae ATCC 700669     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 363686..376022
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN23F_RS13220 - 365948..366070 (-) 123 WP_001815645.1 hypothetical protein -
  SPN23F_RS01940 (SPN23F03790) lepB 366150..366764 (-) 615 WP_001048155.1 signal peptidase I -
  SPN23F_RS01945 (SPN23F03800) rnhC 366776..367648 (-) 873 WP_000146861.1 ribonuclease HIII -
  SPN23F_RS01950 (SPN23F03810) zapA 367735..368037 (+) 303 WP_000002019.1 cell division protein ZapA -
  SPN23F_RS01955 (SPN23F03820) - 368034..368582 (+) 549 WP_000622953.1 CvpA family protein -
  SPN23F_RS01960 (SPN23F03830) mutS/mutS2 368686..371022 (+) 2337 WP_001035036.1 endonuclease MutS2 Machinery gene
  SPN23F_RS01965 (SPN23F03840) - 371365..372687 (+) 1323 WP_000891487.1 alanine/glycine:cation symporter family protein -
  SPN23F_RS01970 (SPN23F03850) - 372905..373453 (+) 549 WP_000206761.1 carboxymuconolactone decarboxylase family protein -
  SPN23F_RS01975 (SPN23F03860) - 373563..374462 (+) 900 WP_000735961.1 TDT family transporter -
  SPN23F_RS01980 (SPN23F03870) serS 374487..375761 (-) 1275 WP_000884265.1 serine--tRNA ligase -

Sequence

Protein


Download         Length: 778 a.a.        Molecular weight: 87707.69 Da        Isoelectric Point: 6.9541

>NTDB_id=29445 SPN23F_RS01960 WP_001035036.1 368686..371022(+) (mutS/mutS2) [Streptococcus pneumoniae ATCC 700669]
MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIKQAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEM
RADLNIEEFLLLKRVLLASRELQNFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTVYIEPREVVKLSEEIASLRADER
YEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRAKVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQD
LTAIVITGPNTGGKTIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNIVDILGKVN
QHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYGIETAFVQNASMEFDTATLRPTYRFMQGVPG
RSNAFEIAKRLGLSEVIVGDASQQIDQDNDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETE
LNKAREQAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAKKKRAPKVGDDIVVLSY
GQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPVKKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFI
DQALLNNMAQVDIIHGIGTGVIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG

Nucleotide


Download         Length: 2337 bp        

>NTDB_id=29445 SPN23F_RS01960 WP_001035036.1 368686..371022(+) (mutS/mutS2) [Streptococcus pneumoniae ATCC 700669]
ATGAATAAGAAAATATTAGAAACATTAGAGTTCGATAAGGTCAAGGCCTTGTTTGAGCCTCATTTGTTGACCGAGCAGGG
CTTGGAGCAATTGAGACAGCTGGCTCCGACTGCCAAAGCAGATAAAATCAAACAGGCTTTTGCTGAGATGAAGGAAATGC
AGGCTCTTTTCGTCGAGCAACCGCATTTTACTATTCTCTCAACTAAGGAAATTGCAGGAGTCTGCAAGAGGTTGGAGATG
AGAGCGGATCTCAATATCGAGGAGTTCCTACTCTTGAAACGCGTGCTTCTTGCCAGCCGAGAACTTCAAAATTTTTACGC
CAATCTGGAAAATGTCAGCTTGGAAGAATTAGCCCTTTGGTTTGAGAAATTACATGATTTTCCGCAATTACAAGGAAATC
TTCAGGCCTTTAATGATGCGGGTTTCATTGAAAATTTTGCCAGTGAAGAATTGGCGCGAATCCGTCGAAAAATACATGAT
AGCGAGAGTCAGGTACGCGATGTTTTACAAGACTTACTCAAGCAAAAAGCGCAGATGTTGACGGAAGGAATTGTTGCTAG
CAGAAATGGCCGTCAGGTTTTACCAGTCAAAAACACCTACCGCAATAAGATTGCAGGTGTCGTTCATGATATTTCTGCTA
GTGGAAACACCGTCTATATCGAACCACGTGAGGTAGTCAAACTGAGCGAAGAAATTGCTAGTCTGCGAGCAGATGAGCGC
TATGAAATGCTTCGCATTCTCCAAGAAATTTCTGAGCGTGTCCGCCCTCATGCGGCTGAGATTGCTAATGACGCTTGGAT
TATCGGTCATCTGGACTTGATTCGTGCCAAGGTTCGATTTATCCAAGAAAGGCAAGCAGTCGTGCCTCAGCTGTCAGAAA
ATCAAGAGATTCAACTGCTCCATGTCTGCCATCCTTTGGTCAAAAATGCCGTCGCAAATGATGTCTATTTTGGTCAAGAT
TTAACAGCTATTGTCATTACAGGTCCCAATACAGGTGGGAAGACCATCATGCTCAAAACTCTGGGCTTGACACAGGTCAT
GGCCCAGTCAGGATTGCCGATTTTAGCAGACAAGGGAAGTCGTGTTGGTATTTTTGAAGAAATCTTTGCTGATATTGGAG
ATGAGCAGTCTATTGAGCAGAGCTTGTCTACCTTCTCTAGCCATATGACCAATATCGTGGATATTCTTGGCAAGGTCAAC
CAACATTCACTCTTACTTTTGGATGAGTTGGGGGCTGGTACTGATCCCCAAGAGGGAGCAGCCCTTGCCATGGCTATTCT
GGAGGACCTTCGCCTGCGTCAAATCAAGACCATGGCGACGACCCACTATCCAGAACTCAAGGCCTACGGTATTGAGACAG
CCTTTGTGCAAAATGCCAGTATGGAGTTTGATACTGCAACTCTTCGCCCGACCTATCGCTTTATGCAGGGTGTTCCTGGC
CGAAGTAATGCCTTTGAAATTGCCAAACGTCTAGGCCTATCTGAAGTTATCGTAGGAGATGCCAGTCAGCAGATCGATCA
GGACAATGACGTCAATCGTATCATTGAGCAATTAGAAGAGCAGACGCTGGAAAGCCGCAAACGTTTGGACAATATCCGTG
AGGTGGAGCAAGAAAATCTCAAGATGAACCGTGCGCTAAAAAAACTCTACAACGAGCTTAATCGTGAAAAGGAAACCGAG
CTTAACAAGGCGCGTGAACAGGCTGCTGAGATTGTGGATATGGCCCTAAGTGAAAGTGACCAGATTCTCAAAAATCTCCA
CAGTAAATCCCAACTCAAGCCCCACGAAATCATTGAAGCCAAGGCCAAGTTGAAAAAATTGGCTCCTGAAAAAGTGGACT
TGTCTAAAAACAAGGTCCTTCAAAAGGCCAAGAAAAAACGAGCTCCAAAGGTGGGAGATGATATCGTGGTTCTCAGTTAT
GGTCAGCGTGGTACCTTGACCAGTCAACTCAAGGACGGCCGCTGGGAAGCCCAAGTTGGCTTGATTAAGATGACCTTGGA
AGAGAAAGAGTTTGATCTTGTTCAAGCCCAGCAAGAAAAACCAGTCAAGAAGAAACAGGTCAATGTTGTGAAACGAACTT
CTGGGCGAGGACCTCAAGCTAGACTGGATCTTCGAGGCAAGCGCTATGAAGAAGCCATGAATGAGCTAGATACCTTCATC
GACCAAGCCTTGCTTAACAATATGGCTCAAGTTGATATCATCCATGGTATCGGAACAGGAGTCATCCGTGAAGGAGTTAC
CAAATACTTGCAAAGAAACAAACATGTCAAGAGTTTCGGCTATGCCCCACAAAATGCTGGAGGCAGTGGTGCGACTATTG
TCACTTTTAAAGGATAG

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(324-506)

Smr domain (Smr)

(702-777)

MutS2 and Smr-associated SH3 domain (MSSS)

(631-670)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B8ZLH4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

40.582

100

0.413