Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   DK182_RS04380 Genome accession   NZ_CP029491
Coordinates   864492..865367 (+) Length   291 a.a.
NCBI ID   WP_019770933.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain 10919     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 859492..870367
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK182_RS04355 (DK181_04355) atpD 860487..861893 (+) 1407 WP_002963082.1 F0F1 ATP synthase subunit beta -
  DK182_RS04360 (DK181_04360) - 861906..862325 (+) 420 WP_002963081.1 F0F1 ATP synthase subunit epsilon -
  DK182_RS04365 (DK181_04365) - 862678..862914 (+) 237 WP_080566229.1 DUF1146 family protein -
  DK182_RS04370 (DK181_04370) murA 862978..864246 (+) 1269 WP_002963079.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  DK182_RS04375 (DK181_04375) - 864246..864437 (+) 192 WP_019769604.1 DNA-directed RNA polymerase subunit beta -
  DK182_RS04380 (DK181_04380) endA 864492..865367 (+) 876 WP_019770933.1 DNA/RNA non-specific endonuclease Machinery gene
  DK182_RS04385 (DK181_04385) pheS 865775..866818 (+) 1044 WP_002963076.1 phenylalanine--tRNA ligase subunit alpha -
  DK182_RS04390 (DK181_04390) - 866837..867358 (+) 522 WP_019770934.1 GNAT family N-acetyltransferase -
  DK182_RS04395 (DK181_04395) pheT 867487..869892 (+) 2406 WP_109833530.1 phenylalanine--tRNA ligase subunit beta -

Sequence

Protein


Download         Length: 291 a.a.        Molecular weight: 31931.66 Da        Isoelectric Point: 10.1097

>NTDB_id=293211 DK182_RS04380 WP_019770933.1 864492..865367(+) (endA) [Streptococcus sobrinus strain 10919]
MVKKSKSSMKREQKALLSLIGLVLVLLLGFVATNDKISNQNPIKHVAQQLTGQNQGRRRSSSSQEAPTQTLADSVMTQEV
KNQLPEQMDWNGAGAYILNNNKTDLDAKVASNPYVNNQTKLIQGQTVPSQANALLAKSTRQYRNRQETGNGSTDWTPAGW
HQKTNLSGAYDHAVDRGHLIAYALAGRLKGFDASTSNPANVAVQTAWANEASSSQSTGQNYYETLIRKALDKNKRVRYRV
TLVYQEDNLIASGSHLEAKSSDGSLEFNVFIPNVQKGISLDYYSGQVSPKS

Nucleotide


Download         Length: 876 bp        

>NTDB_id=293211 DK182_RS04380 WP_019770933.1 864492..865367(+) (endA) [Streptococcus sobrinus strain 10919]
ATGGTGAAAAAATCAAAATCAAGCATGAAGCGAGAGCAAAAGGCCCTTTTGTCCCTAATCGGACTGGTATTGGTTCTGTT
ACTGGGCTTTGTGGCCACTAACGACAAGATTTCTAATCAGAATCCTATCAAGCATGTTGCCCAACAGTTGACTGGACAAA
ATCAAGGAAGAAGGCGCTCAAGTTCAAGCCAGGAGGCTCCAACTCAGACACTTGCTGACAGCGTTATGACTCAGGAAGTC
AAAAATCAGCTTCCGGAACAGATGGACTGGAATGGAGCAGGAGCCTACATTCTCAATAACAACAAGACCGATTTGGATGC
CAAGGTAGCCAGCAACCCCTATGTTAACAATCAAACCAAGCTGATCCAAGGGCAGACGGTTCCTAGTCAGGCCAATGCCC
TGCTGGCTAAATCTACCCGCCAGTACCGCAATCGTCAGGAGACTGGCAATGGATCGACCGACTGGACCCCAGCTGGTTGG
CATCAAAAGACCAACCTCTCAGGAGCTTACGACCACGCAGTCGACCGGGGCCATCTGATTGCTTATGCCCTAGCTGGTAG
ACTTAAGGGCTTCGATGCCTCTACCAGCAATCCCGCCAATGTGGCGGTTCAGACCGCTTGGGCCAACGAGGCCAGCAGCT
CCCAGTCAACTGGTCAAAACTACTATGAAACCCTGATTCGTAAGGCCTTGGACAAAAACAAACGCGTCCGCTATCGGGTA
ACCTTGGTTTACCAAGAGGATAATCTGATTGCTTCTGGCAGTCATTTGGAAGCCAAGTCTTCCGACGGCAGTTTGGAATT
CAACGTCTTCATTCCCAATGTCCAAAAGGGTATCAGCCTAGATTATTATTCGGGACAGGTCTCACCCAAGTCCTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(125-249)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

65.778

77.32

0.509
  endA Streptococcus pneumoniae D39

65.778

77.32

0.509
  endA Streptococcus pneumoniae R6

65.778

77.32

0.509
  endA Streptococcus pneumoniae TIGR4

65.778

77.32

0.509

Multiple sequence alignment