Detailed information NTG0292977

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: DKK89_RS03140
• Genome accession: NZ_CP029474
• Coordinates: 580200..581087 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain USA 100 isolate 30-47
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 575200..586087

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DKK89_RS03105 (DKK89_03105)	-	575219..575311 (+)	93	WP_010956583.1	hypothetical protein	-
DKK89_RS03110 (DKK89_03110)	-	575419..575916 (-)	498	WP_001065268.1	glutathione peroxidase	-
DKK89_RS03115 (DKK89_03115)	-	575926..576186 (-)	261	WP_001791974.1	hypothetical protein	-
DKK89_RS03125 (DKK89_03125)	-	576568..576681 (-)	114	Protein_583	hypothetical protein	-
DKK89_RS03130 (DKK89_03130)	-	577340..579340 (-)	2001	WP_000776750.1	ABC transporter permease	-
DKK89_RS03135 (DKK89_03135)	-	579337..580092 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
DKK89_RS03140 (DKK89_03140)	braS	580200..581087 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
DKK89_RS03145 (DKK89_03145)	braR	581098..581763 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
DKK89_RS03150 (DKK89_03150)	-	581789..581989 (-)	201	WP_000604730.1	hypothetical protein	-
DKK89_RS03155 (DKK89_03155)	-	582187..583611 (+)	1425	WP_000953755.1	alkaline phosphatase	-
DKK89_RS14370	-	583681..583791 (+)	111	Protein_590	hypothetical protein	-
DKK89_RS03165 (DKK89_03165)	-	583894..584349 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
DKK89_RS03170 (DKK89_03170)	-	584594..585355 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=292977 DKK89_RS03140 WP_000143425.1 580200..581087(-) (braS) [Staphylococcus aureus strain USA 100 isolate 30-47]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=292977 DKK89_RS03140 WP_000143425.1 580200..581087(-) (braS) [Staphylococcus aureus strain USA 100 isolate 30-47]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1