Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   DIR45_RS18980 Genome accession   NZ_CP029323
Coordinates   3628201..3628980 (-) Length   259 a.a.
NCBI ID   WP_000421288.1    Uniprot ID   Q81WK7
Organism   Bacillus anthracis strain 17OD930     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3593879..3667804 3628201..3628980 within 0


Gene organization within MGE regions


Location: 3593879..3667804
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DIR45_RS18825 (DIR45_19845) - 3594222..3595892 (-) 1671 WP_000823085.1 ribonuclease J -
  DIR45_RS18835 (DIR45_19855) dapA 3596658..3597536 (-) 879 WP_000564767.1 4-hydroxy-tetrahydrodipicolinate synthase -
  DIR45_RS18840 (DIR45_19860) dapG 3597548..3598780 (-) 1233 WP_000692470.1 aspartate kinase -
  DIR45_RS18845 (DIR45_19865) asd 3598804..3599850 (-) 1047 WP_000414849.1 aspartate-semialdehyde dehydrogenase -
  DIR45_RS18850 (DIR45_19870) dpaB 3600001..3600600 (-) 600 WP_001049484.1 dipicolinate synthase subunit B -
  DIR45_RS18855 (DIR45_19875) dpaA 3600597..3601499 (-) 903 WP_000954726.1 dipicolinic acid synthetase subunit A -
  DIR45_RS18860 (DIR45_19885) - 3601774..3602025 (-) 252 WP_001239752.1 YlmC/YmxH family sporulation protein -
  DIR45_RS18865 (DIR45_19890) - 3602152..3603393 (-) 1242 WP_000592993.1 pitrilysin family protein -
  DIR45_RS18870 (DIR45_19895) - 3603480..3604379 (-) 900 WP_000647529.1 polysaccharide deacetylase family protein -
  DIR45_RS18875 (DIR45_19900) pnp 3604531..3606669 (-) 2139 WP_000076750.1 polyribonucleotide nucleotidyltransferase -
  DIR45_RS18880 (DIR45_19905) rpsO 3606830..3607099 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  DIR45_RS18885 (DIR45_19910) ribF 3607200..3608171 (-) 972 WP_000766711.1 bifunctional riboflavin kinase/FAD synthetase -
  DIR45_RS18890 (DIR45_19915) truB 3608215..3609138 (-) 924 WP_000399357.1 tRNA pseudouridine(55) synthase TruB -
  DIR45_RS18895 (DIR45_19920) rbfA 3609225..3609581 (-) 357 WP_000776441.1 30S ribosome-binding factor RbfA -
  DIR45_RS18900 (DIR45_19925) - 3609597..3609878 (-) 282 WP_000582364.1 DUF503 family protein -
  DIR45_RS18905 (DIR45_19930) infB 3609875..3611935 (-) 2061 WP_000036340.1 translation initiation factor IF-2 -
  DIR45_RS18910 (DIR45_19935) - 3611940..3612251 (-) 312 WP_001286523.1 YlxQ family RNA-binding protein -
  DIR45_RS18915 (DIR45_19940) - 3612252..3612524 (-) 273 WP_000071128.1 YlxR family protein -
  DIR45_RS18920 (DIR45_19945) nusA 3612536..3613642 (-) 1107 WP_000102606.1 transcription termination factor NusA -
  DIR45_RS18925 (DIR45_19950) rimP 3613660..3614130 (-) 471 WP_000359097.1 ribosome maturation factor RimP -
  DIR45_RS18930 (DIR45_19955) - 3614463..3618764 (-) 4302 WP_000059985.1 PolC-type DNA polymerase III -
  DIR45_RS18935 (DIR45_19965) - 3618889..3620589 (-) 1701 WP_000814312.1 proline--tRNA ligase -
  DIR45_RS18940 (DIR45_19970) rseP 3620699..3621955 (-) 1257 WP_001090228.1 RIP metalloprotease RseP -
  DIR45_RS18945 (DIR45_19975) dxr 3621972..3623114 (-) 1143 WP_000790359.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  DIR45_RS18950 (DIR45_19980) cdsA 3623138..3623929 (-) 792 WP_000813581.1 phosphatidate cytidylyltransferase -
  DIR45_RS18955 (DIR45_19985) uppS 3623947..3624723 (-) 777 WP_000971301.1 isoprenyl transferase -
  DIR45_RS18960 (DIR45_19990) frr 3624809..3625366 (-) 558 WP_000531503.1 ribosome recycling factor -
  DIR45_RS18965 (DIR45_19995) pyrH 3625369..3626091 (-) 723 WP_000042663.1 UMP kinase -
  DIR45_RS18970 (DIR45_20000) tsf 3626158..3627045 (-) 888 WP_001018581.1 translation elongation factor Ts -
  DIR45_RS18975 (DIR45_20005) rpsB 3627149..3627850 (-) 702 WP_000111483.1 30S ribosomal protein S2 -
  DIR45_RS18980 (DIR45_20010) codY 3628201..3628980 (-) 780 WP_000421288.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  DIR45_RS18985 (DIR45_20015) hslU 3629058..3630449 (-) 1392 WP_108596888.1 ATP-dependent protease ATPase subunit HslU -
  DIR45_RS18990 (DIR45_20020) hslV 3630472..3631014 (-) 543 WP_000526272.1 ATP-dependent protease proteolytic subunit HslV -
  DIR45_RS18995 (DIR45_20025) xerC 3631057..3631956 (-) 900 WP_001101226.1 tyrosine recombinase XerC -
  DIR45_RS19000 (DIR45_20030) trmFO 3632022..3633326 (-) 1305 WP_001991958.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  DIR45_RS19005 (DIR45_20035) topA 3633377..3635455 (-) 2079 WP_001286969.1 type I DNA topoisomerase -
  DIR45_RS19010 (DIR45_20040) dprA 3635600..3636468 (-) 869 Protein_3689 DNA-processing protein DprA -
  DIR45_RS19015 (DIR45_20045) sucD 3636556..3637458 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  DIR45_RS19020 (DIR45_20050) sucC 3637479..3638639 (-) 1161 WP_001020786.1 ADP-forming succinate--CoA ligase subunit beta -
  DIR45_RS19025 (DIR45_20055) rnhB 3638834..3639607 (-) 774 WP_001174712.1 ribonuclease HII -
  DIR45_RS19030 (DIR45_20060) ylqF 3639659..3640549 (-) 891 WP_000236707.1 ribosome biogenesis GTPase YlqF -
  DIR45_RS19035 (DIR45_20065) lepB 3640570..3641121 (-) 552 WP_000711857.1 signal peptidase I -
  DIR45_RS19040 (DIR45_20070) rplS 3641223..3641567 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  DIR45_RS19045 (DIR45_20075) trmD 3641714..3642448 (-) 735 WP_000686892.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  DIR45_RS19050 (DIR45_20080) rimM 3642448..3642963 (-) 516 WP_000170269.1 ribosome maturation factor RimM -
  DIR45_RS19055 (DIR45_20085) - 3643084..3643311 (-) 228 WP_000737398.1 KH domain-containing protein -
  DIR45_RS19060 (DIR45_20090) rpsP 3643326..3643598 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  DIR45_RS19065 (DIR45_20095) ffh 3643698..3645047 (-) 1350 WP_000863456.1 signal recognition particle protein -
  DIR45_RS19070 (DIR45_20100) - 3645060..3645392 (-) 333 WP_000891062.1 putative DNA-binding protein -
  DIR45_RS19075 (DIR45_20105) ftsY 3645526..3646515 (-) 990 WP_000007650.1 signal recognition particle-docking protein FtsY -
  DIR45_RS19080 (DIR45_20110) smc 3646531..3650100 (-) 3570 WP_000478986.1 chromosome segregation protein SMC -
  DIR45_RS19085 (DIR45_20115) rncS 3650247..3650984 (-) 738 WP_001146873.1 ribonuclease III -
  DIR45_RS19090 (DIR45_20120) acpP 3651043..3651276 (-) 234 WP_000786062.1 acyl carrier protein -
  DIR45_RS19095 (DIR45_20125) fabG 3651346..3652086 (-) 741 WP_000911782.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  DIR45_RS19100 (DIR45_20130) fabD 3652086..3653030 (-) 945 WP_000516948.1 ACP S-malonyltransferase -
  DIR45_RS19105 (DIR45_20135) plsX 3653045..3654037 (-) 993 WP_000684111.1 phosphate acyltransferase PlsX -
  DIR45_RS19110 (DIR45_20140) fapR 3654034..3654627 (-) 594 WP_000747352.1 transcription factor FapR -
  DIR45_RS19115 (DIR45_20145) recG 3654716..3656764 (-) 2049 WP_001006884.1 ATP-dependent DNA helicase RecG -
  DIR45_RS19120 (DIR45_20150) - 3657054..3658730 (-) 1677 WP_000027140.1 DAK2 domain-containing protein -
  DIR45_RS19125 (DIR45_20155) - 3658753..3659115 (-) 363 WP_000021109.1 Asp23/Gls24 family envelope stress response protein -
  DIR45_RS19130 (DIR45_20160) rpmB 3659494..3659682 (+) 189 WP_000124778.1 50S ribosomal protein L28 -
  DIR45_RS19135 (DIR45_20165) spoVM 3659756..3659836 (-) 81 WP_001213599.1 stage V sporulation protein SpoVM -
  DIR45_RS19140 (DIR45_20170) - 3659903..3660583 (-) 681 WP_025388434.1 thiamine diphosphokinase -
  DIR45_RS19145 (DIR45_20175) rpe 3660683..3661327 (-) 645 WP_000589966.1 ribulose-phosphate 3-epimerase -
  DIR45_RS19150 (DIR45_20180) rsgA 3661330..3662211 (-) 882 WP_001113935.1 ribosome small subunit-dependent GTPase A -
  DIR45_RS19155 (DIR45_20185) prkC 3662480..3664453 (-) 1974 WP_000904759.1 serine/threonine protein kinase PrkC -
  DIR45_RS19160 (DIR45_20190) - 3664462..3665214 (-) 753 WP_000648699.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  DIR45_RS19165 (DIR45_20195) rlmN 3665219..3666307 (-) 1089 WP_000450543.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  DIR45_RS19170 (DIR45_20200) rsmB 3666312..3667646 (-) 1335 WP_001249680.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28774.05 Da        Isoelectric Point: 4.7947

>NTDB_id=291645 DIR45_RS18980 WP_000421288.1 3628201..3628980(-) (codY) [Bacillus anthracis strain 17OD930]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLHELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=291645 DIR45_RS18980 WP_000421288.1 3628201..3628980(-) (codY) [Bacillus anthracis strain 17OD930]
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGTCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAGAATGAGCGTATGAAACAAATGCTTGCAGAACGTCAATTCCCAGAAGAGTATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAACAGTGCTTACACAGCATTCCCAGTAGAAAATAAAGAATTATTTGG
TCAAGGTTTAACTACAATCGTACCGATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTTTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATTCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATCGAAGAAGAAGCACGTAGCAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAATTAGAAGCAAT
CGAGCACATCTTCGAAGAATTAAACGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGACCGCGTAGGAATCACTC
GTTCGGTAATCGTAAATGCACTTCGTAAATTAGAAAGTGCTGGTGTAATTGAGTCGCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTATTAAACGACAAATTCTTACATGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81WK7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.081

100

0.811
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459

Multiple sequence alignment