Detailed information NTG0288293

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: C1A39_RS05490
• Genome accession: NZ_CP028896
• Coordinates: 1049090..1049971 (-)
• Length: 293 a.a.
• NCBI ID: WP_011681210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CS5
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1044090..1054971

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C1A39_RS05465 (C1A39_05620)	vicR	1044794..1045501 (-)	708	WP_011681206.1	response regulator YycF	Regulator
C1A39_RS05470 (C1A39_05625)	-	1046028..1046795 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
C1A39_RS05475 (C1A39_05630)	-	1046807..1047640 (+)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
C1A39_RS05480 (C1A39_05635)	-	1047658..1048356 (+)	699	WP_011681209.1	amino acid ABC transporter permease	-
C1A39_RS05485 (C1A39_05640)	-	1048368..1049018 (+)	651	WP_024704148.1	amino acid ABC transporter permease	-
C1A39_RS05490 (C1A39_05645)	endA	1049090..1049971 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
C1A39_RS05495 (C1A39_05650)	-	1050033..1050221 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
C1A39_RS05500 (C1A39_05655)	murA	1050223..1051494 (-)	1272	WP_024704149.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
C1A39_RS05505 (C1A39_05660)	-	1051564..1051800 (-)	237	WP_002946959.1	DUF1146 family protein	-
C1A39_RS05510 (C1A39_05665)	galE	1051989..1053002 (-)	1014	WP_014621668.1	UDP-glucose 4-epimerase GalE	-
C1A39_RS05515 (C1A39_05670)	-	1053017..1053451 (-)	435	WP_231107205.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=288293 C1A39_RS05490 WP_011681210.1 1049090..1049971(-) (endA) [Streptococcus thermophilus strain CS5]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=288293 C1A39_RS05490 WP_011681210.1 1049090..1049971(-) (endA) [Streptococcus thermophilus strain CS5]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594