Detailed information NTG0288027

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DB248_RS05115
• Genome accession: NZ_CP028841
• Coordinates: 951334..952170 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain CCUG 4207
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 946334..957170

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DB248_RS05085 (DB248_05090)	-	946888..947256 (+)	369	WP_010922310.1	hypothetical protein	-
DB248_RS05090 (DB248_05095)	-	947306..948217 (-)	912	WP_010922311.1	diacylglycerol kinase family protein	-
DB248_RS05095 (DB248_05100)	-	948334..948984 (-)	651	WP_002984629.1	hemolysin III family protein	-
DB248_RS05100 (DB248_05105)	-	948981..949421 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
DB248_RS05105 (DB248_05110)	ylqF	949640..950488 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
DB248_RS05110 (DB248_05115)	-	950478..951269 (+)	792	WP_011285534.1	ribonuclease HII	-
DB248_RS05115 (DB248_05120)	dprA	951334..952170 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
DB248_RS05120 (DB248_05125)	topA	952277..954406 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
DB248_RS10130	-	954481..955363 (-)	883	Protein_946	LysR family transcriptional regulator	-
DB248_RS05135 (DB248_05140)	-	955376..955921 (+)	546	Protein_947	PTS sugar transporter subunit IIC	-
DB248_RS05140 (DB248_05145)	-	955936..956928 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=288027 DB248_RS05115 WP_010922314.1 951334..952170(+) (dprA) [Streptococcus pyogenes strain CCUG 4207]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=288027 DB248_RS05115 WP_010922314.1 951334..952170(+) (dprA) [Streptococcus pyogenes strain CCUG 4207]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367