Detailed information NTG0288017

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DB248_RS02300
• Genome accession: NZ_CP028841
• Coordinates: 413856..414857 (+)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain CCUG 4207
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 408856..419857

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DB248_RS02275 (DB248_02275)	-	409530..410213 (-)	684	WP_002990714.1	DUF969 domain-containing protein	-
DB248_RS02280 (DB248_02280)	-	410424..411350 (-)	927	WP_002994177.1	glycosyltransferase family 2 protein	-
DB248_RS02285 (DB248_02285)	-	411495..411872 (-)	378	WP_002985686.1	VOC family protein	-
DB248_RS02290 (DB248_02290)	-	411883..412548 (-)	666	WP_010921982.1	NAD(P)H-dependent oxidoreductase	-
DB248_RS02295 (DB248_02295)	-	412597..413682 (-)	1086	WP_002985682.1	aminopeptidase P family protein	-
DB248_RS02300 (DB248_02300)	ccpA	413856..414857 (+)	1002	WP_002985680.1	catabolite control protein A	Regulator
DB248_RS02305 (DB248_02305)	-	414988..415986 (+)	999	WP_002985678.1	glycosyltransferase family 4 protein	-
DB248_RS02310 (DB248_02310)	-	415988..417322 (+)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
DB248_RS02315 (DB248_02315)	thrS	417744..419687 (+)	1944	WP_010921984.1	threonine--tRNA ligase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=288017 DB248_RS02300 WP_002985680.1 413856..414857(+) (ccpA) [Streptococcus pyogenes strain CCUG 4207]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=288017 DB248_RS02300 WP_002985680.1 413856..414857(+) (ccpA) [Streptococcus pyogenes strain CCUG 4207]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGCCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559