Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   EHS18_RS05965 Genome accession   NZ_CP034098
Coordinates   1205941..1206714 (+) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain 80wphwpl_v1     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1200941..1211714
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHS18_RS05945 (EHS18_05945) trmFO 1201284..1202591 (+) 1308 WP_000195249.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  EHS18_RS05950 (EHS18_05950) xerC 1203009..1203905 (+) 897 WP_001015609.1 tyrosine recombinase XerC -
  EHS18_RS05955 (EHS18_05955) hslV 1203902..1204447 (+) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  EHS18_RS05960 (EHS18_05960) hslU 1204513..1205916 (+) 1404 WP_000379050.1 ATP-dependent protease ATPase subunit HslU -
  EHS18_RS05965 (EHS18_05965) codY 1205941..1206714 (+) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  EHS18_RS05970 (EHS18_05970) - 1206765..1206857 (+) 93 WP_031788481.1 hypothetical protein -
  EHS18_RS05975 (EHS18_05975) rpsB 1207056..1207823 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  EHS18_RS05980 (EHS18_05980) - 1207857..1207970 (+) 114 WP_001791405.1 hypothetical protein -
  EHS18_RS05985 (EHS18_05985) tsf 1208005..1208886 (+) 882 WP_000201388.1 translation elongation factor Ts -
  EHS18_RS05990 (EHS18_05990) pyrH 1209023..1209745 (+) 723 WP_000057330.1 UMP kinase -
  EHS18_RS05995 (EHS18_05995) frr 1209764..1210318 (+) 555 WP_001280006.1 ribosome recycling factor -
  EHS18_RS06000 (EHS18_06000) - 1210691..1211461 (+) 771 WP_000473705.1 isoprenyl transferase -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=287730 EHS18_RS05965 WP_000055337.1 1205941..1206714(+) (codY) [Staphylococcus aureus strain 80wphwpl_v1]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=287730 EHS18_RS05965 WP_000055337.1 1205941..1206714(+) (codY) [Staphylococcus aureus strain 80wphwpl_v1]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGCGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACACGATG
ACTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTTGGCGGTACAGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428

Multiple sequence alignment