Detailed information    

insolico Bioinformatically predicted

Overview

Name   recD/recD2/recDB   Type   Machinery gene
Locus tag   EHF40_RS08220 Genome accession   NZ_CP033907
Coordinates   1577059..1579512 (+) Length   817 a.a.
NCBI ID   WP_011528948.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Duke-Large     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1572059..1584512
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHF40_RS08200 (EHF40_08200) - 1574482..1575027 (-) 546 WP_002983087.1 CvpA family protein -
  EHF40_RS08205 (EHF40_08205) - 1575030..1575338 (-) 309 WP_002993251.1 hypothetical protein -
  EHF40_RS08210 (EHF40_08210) rnhC 1575495..1576397 (+) 903 WP_011528946.1 ribonuclease HIII -
  EHF40_RS08215 (EHF40_08215) lepB 1576408..1577001 (+) 594 WP_021299037.1 signal peptidase I -
  EHF40_RS08220 (EHF40_08220) recD/recD2/recDB 1577059..1579512 (+) 2454 WP_011528948.1 ATP-dependent RecD-like DNA helicase Machinery gene
  EHF40_RS08225 (EHF40_08225) - 1579603..1580085 (+) 483 WP_011528949.1 hypothetical protein -
  EHF40_RS08230 (EHF40_08230) dinB 1580178..1581272 (-) 1095 WP_002983063.1 DNA polymerase IV -
  EHF40_RS08235 (EHF40_08235) pflB 1581481..1583808 (+) 2328 WP_002988233.1 formate C-acetyltransferase -

Sequence

Protein


Download         Length: 817 a.a.        Molecular weight: 91394.30 Da        Isoelectric Point: 4.6433

>NTDB_id=285855 EHF40_RS08220 WP_011528948.1 1577059..1579512(+) (recD/recD2/recDB) [Streptococcus pyogenes strain Duke-Large]
MEHFFTGTVDRIIFENAANFFKILLLAIEDTDSDIDDFEIIITGTMADIIEGDDYTFWGELTQHPKYGQQLKLSRYQKIK
PSSSGLVNYFSSDHFKGIGKKTAEKIIALYGHNTIDHILEDPSKLETISGLSKANRQAFVAKLKLNYGTEQLIAGLVELG
LSNRFALQAFEKYKEEALDLVKENPYQLVEDLQGFGFKMADALAENLGIESDSPKRFRAALLHCLLEESINRGDTYVQAR
QLLDFAITLLEDARQVECDPAAVAEQLSELIIEGKIKNSDTKLFDASLYFAEEGIANNISRLLDTPLSQSFSHDTIQTTI
QAVQKDFAITYDQVQQEAITKALTSKVFLLTGGPGTGKTTVIRGILQAYANLHQIDLDKKDLPILLAAPTGRAARRMNEL
TGLPSATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLGAINSTTQVIIVGDSDQLPSVGPGQVLSDLL
KVNSLPQIALQKIFRQSQESTIVNLADQMRRGILAADFRDKKADRSYFEAQAAFIPDMIQKIVLSAIKSGIPAEEIQILA
PMYKGQAGINHLNQLMQELLNPLQGQTEFLFNDTHFRKGDKVLHLVNDAQLNVFNGDIGYITDLIPAKYTESKQDELILD
FDGSEVTYPRNEWLKLTLAYAMSIHKSQGSEFQVVILPITRQSGRLLQRNVIYTAITRSKSKLILLGEYTAFEYAIKHEG
DKRQTYLIERFQEQSDLASSQPNQELKSKEQTSLFSNTATLEDDSQKSSSQSTNSNPTENSQSDNDDFRLTPENYSTIDS
MIGLTESDIALFFQKKS

Nucleotide


Download         Length: 2454 bp        

>NTDB_id=285855 EHF40_RS08220 WP_011528948.1 1577059..1579512(+) (recD/recD2/recDB) [Streptococcus pyogenes strain Duke-Large]
ATGGAACACTTTTTTACTGGTACTGTTGACCGCATTATCTTTGAAAATGCAGCTAATTTTTTTAAAATTCTCCTCCTTGC
CATCGAAGACACAGATAGTGATATTGACGACTTTGAAATCATTATCACAGGGACGATGGCTGATATTATTGAAGGAGATG
ACTACACCTTTTGGGGGGAATTGACCCAGCACCCTAAATATGGACAGCAACTCAAACTAAGCCGTTACCAAAAAATCAAA
CCTAGTTCATCTGGTTTGGTTAATTATTTCTCTAGCGACCATTTTAAGGGGATTGGTAAAAAAACAGCGGAGAAAATCAT
TGCGCTATATGGTCATAATACCATTGACCATATTTTAGAAGACCCAAGCAAATTAGAAACTATCTCTGGCCTATCTAAGG
CTAATCGTCAAGCCTTTGTCGCTAAACTAAAATTGAATTACGGCACAGAGCAACTGATTGCTGGTCTCGTCGAACTTGGC
CTTAGCAACCGTTTTGCTCTTCAAGCGTTTGAAAAGTATAAAGAAGAGGCTCTTGACCTTGTTAAAGAAAATCCCTATCA
GTTAGTCGAAGATCTACAAGGTTTTGGGTTTAAAATGGCAGATGCTCTCGCTGAAAACTTAGGGATTGAAAGCGACTCTC
CGAAACGTTTTCGTGCAGCCCTCCTTCACTGTCTCTTGGAAGAATCCATCAATCGAGGAGATACTTATGTCCAAGCACGA
CAATTATTAGACTTTGCCATCACACTCCTTGAAGATGCACGTCAAGTAGAATGTGATCCTGCTGCTGTGGCTGAACAACT
AAGCGAGTTGATCATAGAGGGCAAAATCAAAAACAGTGACACCAAACTGTTTGATGCTAGCCTTTATTTTGCTGAAGAAG
GGATTGCTAACAACATCTCTCGTCTCTTAGATACTCCTTTAAGTCAGTCATTTAGTCATGATACCATTCAAACAACCATC
CAAGCCGTTCAAAAAGACTTTGCCATCACCTATGACCAAGTGCAGCAAGAAGCCATTACTAAGGCCTTAACCAGCAAGGT
CTTTCTCCTAACAGGTGGTCCCGGAACAGGAAAAACAACTGTTATTCGAGGTATTTTGCAGGCTTACGCGAACCTGCATC
AGATTGATTTGGATAAAAAAGACCTTCCTATCTTGTTAGCAGCTCCAACAGGTCGAGCTGCACGTCGCATGAATGAGTTG
ACTGGACTTCCTAGCGCAACCATCCACAGGCACTTAGGCCTCAATGGCGACAACGATTACCAAGCCATGGAGGATTATCT
AGACTGCGACTTGCTGATTGTCGATGAATTTTCAATGGTGGATACCTGGCTTGCCAACCAGTTGTTAGGAGCGATTAACT
CAACAACTCAAGTGATTATTGTCGGAGATAGTGACCAGCTTCCTTCGGTTGGACCCGGTCAAGTCCTGTCAGATCTTTTA
AAAGTCAATAGCCTGCCCCAAATCGCCTTGCAAAAGATATTTCGTCAATCCCAAGAATCTACTATTGTCAATTTGGCAGA
CCAGATGCGTCGAGGAATCTTAGCTGCTGACTTTCGTGATAAAAAAGCTGACCGTTCTTATTTTGAAGCCCAAGCAGCCT
TTATCCCTGACATGATTCAAAAAATTGTCCTATCTGCTATTAAAAGTGGCATCCCTGCTGAGGAAATTCAAATTTTAGCA
CCTATGTACAAAGGACAAGCTGGCATCAATCATCTTAATCAACTCATGCAAGAACTTCTCAATCCCTTGCAAGGACAAAC
AGAATTTCTGTTCAATGATACGCATTTTCGTAAAGGTGATAAAGTCCTGCACTTAGTCAACGATGCTCAGTTGAATGTCT
TTAACGGGGATATTGGTTATATTACAGATTTGATTCCTGCTAAATACACCGAATCTAAGCAAGACGAATTAATCTTAGAT
TTTGACGGTAGCGAAGTCACGTACCCTAGAAATGAATGGCTAAAATTAACCCTGGCCTATGCCATGAGCATTCATAAATC
GCAAGGGAGTGAGTTTCAAGTGGTGATTTTACCTATCACACGCCAAAGCGGCCGACTCTTGCAACGAAATGTGATTTACA
CGGCCATTACTCGGTCTAAAAGTAAGTTAATTCTGTTGGGAGAATATACTGCCTTTGAGTATGCTATTAAACACGAAGGC
GATAAACGCCAAACCTACTTGATCGAACGCTTCCAAGAACAATCCGACTTAGCCTCCTCTCAACCTAACCAAGAGCTAAA
ATCAAAAGAGCAGACCTCCCTTTTTTCTAATACGGCAACCCTTGAGGACGACTCTCAAAAATCTTCCTCTCAATCAACAA
ACTCTAACCCCACTGAGAACTCTCAGTCAGATAATGATGATTTTAGGTTAACACCTGAGAATTATTCGACTATCGATTCG
ATGATAGGGCTTACAGAGTCAGATATTGCCCTCTTTTTCCAGAAAAAATCCTAG

Domains

Predicted by InterProScan.

UvrD-like helicase C-terminal domain (UvrD_C_2)

(659-706)

Helix-hairpin-helix containing domain (HHH_RecD2)

(147-236)

AAA domain (AAA_30)

(331-522)

ATP-dependent RecD-like DNA helicase SH3 domain (SH3_13)

(572-641)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recD/recD2/recDB Bacillus subtilis subsp. subtilis str. 168

41.777

92.289

0.386

Multiple sequence alignment