Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   EB817_RS02140 Genome accession   NZ_CP033336
Coordinates   397920..398702 (+) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain TSPY165     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 392920..403702
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EB817_RS02120 (EB817_02125) - 393258..394223 (-) 966 WP_014407795.1 asparaginase -
  EB817_RS02125 (EB817_02130) - 394295..395683 (+) 1389 WP_009881044.1 Cof-type HAD-IIB family hydrolase -
  EB817_RS02130 (EB817_02135) - 395805..396257 (-) 453 WP_164976415.1 universal stress protein -
  EB817_RS02135 (EB817_02140) - 396488..397702 (+) 1215 WP_129304494.1 pyridoxal phosphate-dependent aminotransferase -
  EB817_RS02140 (EB817_02145) codY 397920..398702 (+) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  EB817_RS02145 (EB817_02150) - 398849..399403 (+) 555 WP_002992568.1 isochorismatase family cysteine hydrolase -
  EB817_RS02155 (EB817_02160) - 399880..400165 (+) 286 Protein_360 putative PEP-binding protein -
  EB817_RS02160 (EB817_02165) gatC 400397..400699 (+) 303 WP_101248439.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  EB817_RS02165 (EB817_02170) gatA 400699..402165 (+) 1467 WP_129304496.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  EB817_RS02170 (EB817_02175) gatB 402165..403604 (+) 1440 WP_129304498.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=283066 EB817_RS02140 WP_002983278.1 397920..398702(+) (codY) [Streptococcus pyogenes strain TSPY165]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=283066 EB817_RS02140 WP_002983278.1 397920..398702(+) (codY) [Streptococcus pyogenes strain TSPY165]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACATTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAGTTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAATTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAGAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504