Detailed information NTG0281035

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: D4H43_RS06600
• Genome accession: NZ_CP032911
• Coordinates: 1363720..1366302 (-)
• Length: 860 a.a.
• NCBI ID: WP_139544419.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain 19-A-EK3
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1358720..1371302

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D4H43_RS06580	-	1359568..1360766 (-)	1199	Protein_1261	DNA type IV secretion system protein ComB10	-
D4H43_RS06585	-	1360763..1362430 (-)	1668	WP_139544417.1	TrbG/VirB9 family P-type conjugative transfer protein	-
D4H43_RS06590	-	1362427..1363596 (-)	1170	WP_139544418.1	VirB8/TrbF family protein	-
D4H43_RS06595	-	1363589..1363723 (-)	135	WP_000738749.1	hypothetical protein	-
D4H43_RS06600	comB4	1363720..1366302 (-)	2583	WP_139544419.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
D4H43_RS06605	-	1366302..1366538 (-)	237	WP_139544420.1	hypothetical protein	-
D4H43_RS06610	comB3	1366549..1366812 (-)	264	WP_128036898.1	competence protein ComB	Machinery gene
D4H43_RS06615	comB2	1366824..1367108 (-)	285	WP_000736106.1	TrbC/VirB2 family protein	Machinery gene
D4H43_RS06620	-	1367105..1367584 (-)	480	WP_033749032.1	hypothetical protein	-
D4H43_RS06625	-	1367577..1367807 (-)	231	WP_000189076.1	hypothetical protein	-
D4H43_RS06630	-	1367810..1368598 (-)	789	WP_139544421.1	integrase	-
D4H43_RS06635	-	1368734..1369117 (+)	384	WP_120957918.1	hypothetical protein	-
D4H43_RS08390	-	1369509..1369676 (-)	168	WP_201737091.1	hypothetical protein	-
D4H43_RS06640	-	1369740..1370042 (-)	303	WP_139544422.1	hypothetical protein	-
D4H43_RS06645	-	1370062..1371054 (-)	993	WP_108169690.1	ketoacyl-ACP synthase III	-

Sequence

Protein

• Length: 860 a.a.
• Molecular weight: 98871.99 Da
• Isoelectric Point: 8.7977

>NTDB_id=281035 D4H43_RS06600 WP_139544419.1 1363720..1366302(-) (comB4) [Helicobacter pylori strain 19-A-EK3]
MLESTLKYCKEKTIDLLAGFVPKTYSMTEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFETITSNVKSFFEKKKLEMTTSISEELEES
SKEDKQENENSSNETHSNTSSKKDKKNKFKKKITFSTTSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNVHFKKDYFVIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDVIFHIRSLGQFESL
NFLKTKKKLTLSKIVKADIDNYIELVQANRLSMQECALNLVIRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYF
SFFPNNANINPRMRNQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGATGAGKTTLISYLMMSALKYSNIDILALDRLNGLYSFTKYFDGIYNQGENFHINPFSLEDSATNRAFLLHFYAQM
AKVDSYDKHNDKIEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNSIVKTNTNILDSSFEDYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDNDAGLLAYYVFHKMIDRALKINRGFLCFIDEFKSYAQNEMMNKEINKIITQARKANG
VIVLALQDINQLSEVKNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIENLIKHYPTTWKEVFVNNTYQKFDDKKHLEKVLCPT

Nucleotide

• Length: 2583 bp

>NTDB_id=281035 D4H43_RS06600 WP_139544419.1 1363720..1366302(-) (comB4) [Helicobacter pylori strain 19-A-EK3]
ATGTTAGAAAGCACCCTTAAATATTGCAAGGAAAAAACCATAGACCTTTTAGCAGGGTTTGTGCCAAAAACCTATTCTAT
GACAGAGGAATGCAATATTTTAGGCTTGTATGATGATACTTTCATCATCACTAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCAAACTTAATGCAAAAAGATTTGGAGGGCTATTTTGATACAAGGCAAAATGTTTTAAAC
ACCATTAGTAAAGACATTCAATTAAGGATTGTCGCTAAAAGGCGTAAAGAATTTATCAACCAAAGCCCAAATATTGATAA
CCCATACGCAAAAGCCATTATCACGCAATTTGAAAGCAAGGAAATCTATAAAACAGAGTATTTTTTAGTGTTTGAAACTA
TCACTTCTAATGTCAAGTCTTTCTTTGAAAAAAAGAAATTGGAAATGACTACTTCAATTAGTGAAGAGTTAGAAGAAAGC
TCTAAAGAAGATAAACAAGAGAATGAAAATAGCTCCAATGAAACTCATTCAAACACAAGCTCTAAAAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGATAACCTTTAGCACCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTAAAAAACG
CATTAAGGGAGTTTAAACCCACTCTTTTAAATTCTAAAGAAGTGTTGAATTTTTATGCAGAATATATCAATGGCAAATAT
ATCGCCTTTAATCCTAAATTAAAGCGATTAAGCGATAGCTATATTGCATCTAATGTGCATTTTAAGAAAGATTACTTTGT
CATTGAATTTCAAAATCAAAGCACTTTTTGTGCGTGTGTGGGGATTAAAAACTATGAGAGTGAAGAAATTTCTTCACTCC
CCATTTCTACCCTTTTACACACCCAAATTGAATTAGATGTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGCCTG
AATTTTTTAAAAACTAAGAAAAAGCTCACGCTTTCTAAAATAGTAAAAGCTGATATTGATAATTATATAGAATTAGTGCA
AGCCAATCGTTTGAGCATGCAAGAGTGTGCTTTAAACTTAGTTATAAGGGCTAAAAGTAAAGCTAAATTAGACAAGTCTT
TAAAAGAGATTTTATCCTTGCTTAATAATGCTGGACTAGGCAGTGTTACAGAAACTATAGGGCTAAAACCATCTTATTTT
TCATTCTTCCCAAATAACGCCAATATCAATCCTAGAATGAGAAATCAAACTTCCCAAGTGATTGCCTCTTTAATCTTGTT
TGAGAAAAATAATACAGGTTTTAGGGCAAATTCATGGGGGGATATGCCCTTATCTGTGTTTAAGAACCTAGACCATAGCC
CTTATTTGTTTAATTTTCATAATCAAGAAGTCAAACATAAGGGCGTGTTAGCCCACAATGTCGCACGAGTAGTGGGACAT
ACCATGATTATAGGAGCAACAGGTGCTGGTAAAACCACACTCATTAGCTATTTGATGATGAGTGCTTTAAAATATTCTAA
CATTGATATTTTAGCTCTTGATAGACTAAATGGTTTGTATTCCTTTACCAAGTATTTTGATGGGATTTATAATCAAGGCG
AAAACTTTCATATTAACCCTTTTTCATTAGAAGATAGCGCAACTAATAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTAGATAGCTATGACAAACATAATGATAAGATAGAAGATAGAACAGCTCTTTTAAACGCTATTGATACCATGTA
TAGAAATTATAACGATGAAGTCAAACAAGCCAAATTCAGCAACCAAGAATTACCACTTCCTTTTGATTTAAAAGAGTTTG
TCAATTCCATTGTTAAAACCAATACAAACATTTTAGATAGCAGTTTTGAAGACTATTTAAAATCTTCCTTATTTTCTAGC
CGAATGGATAGCCTAGATTTTAAAACTCGTATTAGCACCATAAATACTGATAGCATTTTACACAATGATAATGACGCTGG
GCTTTTAGCTTATTATGTGTTTCATAAGATGATTGATAGAGCTTTGAAAATCAATCGTGGGTTTTTATGTTTTATTGATG
AGTTTAAATCTTACGCTCAAAATGAAATGATGAATAAAGAAATCAATAAAATCATCACGCAAGCTAGAAAGGCTAATGGG
GTCATTGTTCTAGCCTTACAAGATATTAACCAACTTAGTGAAGTGAAAAACGCTCAAAGCTTTATTAAAAATATGGGGCA
ATTAATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTAAGTTCTTTGGGTAATTACTTACAAATCTTTAGCTCCAATTCTAGCATGGTAGAACACATTGAAAATCT
TATTAAGCATTACCCTACTACTTGGAAAGAAGTCTTTGTCAATAACACCTATCAAAAATTTGATGACAAAAAACACTTAG
AAAAGGTGCTTTGCCCAACATGA

Domains

Predicted by InterProScan.

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (437-505)

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	46.73	97.791	0.457