Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   C7K40_RS09460 Genome accession   NZ_CP027771
Coordinates   624162..625028 (+) Length   288 a.a.
NCBI ID   WP_023612376.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain DMG1800716     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 619162..630028
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7K40_RS03245 (C7K40_03245) - 619203..620078 (+) 876 WP_002985236.1 F0F1 ATP synthase subunit gamma -
  C7K40_RS03250 (C7K40_03250) atpD 620240..621646 (+) 1407 WP_011017611.1 F0F1 ATP synthase subunit beta -
  C7K40_RS03255 (C7K40_03255) - 621659..622075 (+) 417 WP_002985233.1 F0F1 ATP synthase subunit epsilon -
  C7K40_RS03260 (C7K40_03260) - 622362..622598 (+) 237 WP_009881177.1 DUF1146 family protein -
  C7K40_RS03265 (C7K40_03265) murA 622663..623934 (+) 1272 WP_002994428.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  C7K40_RS03270 (C7K40_03270) - 623938..624126 (+) 189 WP_011017613.1 DNA-directed RNA polymerase subunit beta -
  C7K40_RS09460 endA 624162..625028 (+) 867 WP_023612376.1 DNA/RNA non-specific endonuclease Machinery gene
  C7K40_RS03280 (C7K40_03280) pheS 625311..626354 (+) 1044 WP_063629531.1 phenylalanine--tRNA ligase subunit alpha -
  C7K40_RS03285 (C7K40_03285) pheT 626564..628969 (+) 2406 WP_063629532.1 phenylalanine--tRNA ligase subunit beta -
  C7K40_RS03290 (C7K40_03290) - 629080..629457 (+) 378 WP_002993028.1 OsmC family protein -
  C7K40_RS03295 (C7K40_03295) - 629450..629836 (+) 387 WP_002990406.1 YbgA family protein -

Sequence

Protein


Download         Length: 288 a.a.        Molecular weight: 32087.59 Da        Isoelectric Point: 10.5080

>NTDB_id=280474 C7K40_RS09460 WP_023612376.1 624162..625028(+) (endA) [Streptococcus pyogenes strain DMG1800716]
MLAKKKRKRVLNSFLLILLVLGSNCLAKSDFIASNHPIKQLYQTLVGEKKKSLLTHNNLPADVPTEALAASVLTPSIKKQ
LGPDVQWNGAGAYIINRNKTDLNAKVASLPYANNETKWVQEQKVPKRANALLTKSTRQYRNRYQTDNAYRNFKPAGWHRL
HHLKGSYDHAVDRGHLLGYALVGGLKGLDASTGNPDNIATQLSWANQANKPYSTGQNYYEGLVRRALDKGHRVRYRVTLL
YDGDNLLASGSHLEAKSSDGSLTFNVFVPNVQPGLTVDYRTRQIAINL

Nucleotide


Download         Length: 867 bp        

>NTDB_id=280474 C7K40_RS09460 WP_023612376.1 624162..625028(+) (endA) [Streptococcus pyogenes strain DMG1800716]
ATGTTAGCAAAGAAAAAACGAAAAAGGGTGCTTAATTCCTTCTTATTGATTTTGTTAGTGTTGGGGTCTAACTGCCTTGC
TAAGAGTGATTTCATAGCTAGCAATCACCCTATCAAGCAACTTTATCAGACTCTTGTTGGGGAGAAGAAAAAATCATTAC
TCACACATAATAATTTGCCCGCTGATGTTCCCACAGAAGCTCTGGCGGCATCGGTATTAACACCATCAATCAAAAAGCAA
CTAGGTCCAGATGTTCAGTGGAATGGAGCAGGCGCCTATATTATCAACAGGAACAAAACAGATTTAAATGCTAAGGTAGC
CAGTCTGCCCTATGCCAACAATGAAACCAAATGGGTGCAAGAGCAAAAGGTTCCTAAAAGAGCTAATGCCTTACTTACTA
AGTCGACACGACAGTATCGAAATCGCTATCAAACGGACAATGCTTATCGTAACTTTAAGCCAGCAGGTTGGCACCGATTG
CACCACTTAAAAGGAAGTTATGATCACGCGGTTGATAGAGGGCATTTGCTAGGTTATGCTTTAGTTGGTGGACTGAAAGG
TTTAGATGCTTCTACCGGTAATCCTGATAATATTGCCACTCAACTAAGTTGGGCTAATCAAGCAAATAAACCCTACTCGA
CAGGTCAGAATTACTATGAAGGTTTAGTACGTCGTGCTTTAGATAAGGGGCATCGCGTCCGCTACCGTGTCACCCTACTT
TATGATGGTGATAATCTACTAGCCAGTGGTAGCCATTTGGAGGCTAAATCCTCTGATGGCAGCTTGACTTTTAACGTGTT
TGTTCCAAATGTCCAACCAGGATTGACCGTTGATTATAGGACGAGACAAATAGCTATCAATCTCTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(111-246)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

58.65

82.292

0.483
  endA Streptococcus pneumoniae D39

58.65

82.292

0.483
  endA Streptococcus pneumoniae R6

58.65

82.292

0.483
  endA Streptococcus pneumoniae TIGR4

58.65

82.292

0.483

Multiple sequence alignment