Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   D5S13_RS00220 Genome accession   NZ_CP032821
Coordinates   49248..50021 (-) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain JDFM SA01     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 44248..55021
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D5S13_RS00185 (D5S13_00038) - 44501..45271 (-) 771 WP_000473699.1 isoprenyl transferase -
  D5S13_RS00190 (D5S13_00039) frr 45644..46198 (-) 555 WP_001280004.1 ribosome recycling factor -
  D5S13_RS00195 (D5S13_00040) pyrH 46217..46939 (-) 723 WP_000057330.1 UMP kinase -
  D5S13_RS00200 (D5S13_00041) tsf 47076..47957 (-) 882 WP_000201387.1 translation elongation factor Ts -
  D5S13_RS00205 - 47992..48105 (-) 114 WP_001789890.1 hypothetical protein -
  D5S13_RS00210 (D5S13_00042) rpsB 48139..48906 (-) 768 WP_000268484.1 30S ribosomal protein S2 -
  D5S13_RS00215 - 49105..49197 (-) 93 WP_001790530.1 hypothetical protein -
  D5S13_RS00220 (D5S13_00043) codY 49248..50021 (-) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  D5S13_RS00225 (D5S13_00044) hslU 50046..51449 (-) 1404 WP_263258560.1 ATP-dependent protease ATPase subunit HslU -
  D5S13_RS00230 (D5S13_00045) hslV 51515..52060 (-) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  D5S13_RS00235 (D5S13_00046) xerC 52057..52953 (-) 897 WP_001015597.1 tyrosine recombinase XerC -
  D5S13_RS00240 (D5S13_00047) trmFO 53370..54677 (-) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=278737 D5S13_RS00220 WP_000055337.1 49248..50021(-) (codY) [Staphylococcus aureus strain JDFM SA01]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=278737 D5S13_RS00220 WP_000055337.1 49248..50021(-) (codY) [Staphylococcus aureus strain JDFM SA01]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACTATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTAGGCGGTACGGAAGGTCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428

Multiple sequence alignment