Detailed information NTG0278548

Bioinformatically predicted

Overview

• Name: proC
• Type: Machinery gene
• Locus tag: DSM104626_RS03830
• Genome accession: NZ_CP027634
• Coordinates: 745530..746267 (-)
• Length: 245 a.a.
• NCBI ID: WP_002780246.1
• Uniprot ID: A0A5T1L8T6
• Organism: Campylobacter coli strain meC0281
• Function: DNA uptake (predicted from homology) DNA binding and uptake

Genomic Context

Location: 740530..751267

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DSM104626_RS03790 (DSM104626_00761)	-	740643..741404 (+)	762	WP_072212081.1	ATP-binding protein	-
DSM104626_RS03795 (DSM104626_00762)	-	741401..742084 (+)	684	WP_002791740.1	3-methyladenine DNA glycosylase	-
DSM104626_RS03800 (DSM104626_00763)	thiD	742084..742896 (+)	813	WP_002786353.1	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	-
DSM104626_RS03805 (DSM104626_00764)	thiE	742886..743518 (+)	633	WP_002783359.1	thiamine phosphate synthase	-
DSM104626_RS03810 (DSM104626_00765)	-	743496..744125 (+)	630	WP_002783358.1	uroporphyrinogen-III synthase	-
DSM104626_RS03815 (DSM104626_00766)	-	744118..744570 (-)	453	WP_002777117.1	hypothetical protein	-
DSM104626_RS03820 (DSM104626_00767)	-	744567..745235 (-)	669	WP_002790524.1	hypothetical protein	-
DSM104626_RS03825 (DSM104626_00768)	-	745228..745533 (-)	306	WP_052774393.1	hypothetical protein	-
DSM104626_RS03830 (DSM104626_00769)	proC	745530..746267 (-)	738	WP_002780246.1	pyrroline-5-carboxylate reductase	Machinery gene
DSM104626_RS03835 (DSM104626_00770)	fliW	746267..746656 (-)	390	WP_002777093.1	flagellar assembly protein FliW	-
DSM104626_RS03840 (DSM104626_00771)	bamD	746820..747467 (+)	648	WP_002777091.1	outer membrane protein assembly factor BamD	-
DSM104626_RS03845 (DSM104626_00772)	lon	747483..749858 (+)	2376	WP_002783351.1	endopeptidase La	-
DSM104626_RS03850 (DSM104626_00773)	rpsR	749914..750174 (-)	261	WP_002777087.1	30S ribosomal protein S18	-
DSM104626_RS03855 (DSM104626_00774)	-	750185..750733 (-)	549	WP_002777084.1	single-stranded DNA-binding protein	-
DSM104626_RS03860 (DSM104626_00775)	rpsF	750742..751119 (-)	378	WP_002777082.1	30S ribosomal protein S6	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 26797.20 Da
• Isoelectric Point: 9.3032

>NTDB_id=278548 DSM104626_RS03830 WP_002780246.1 745530..746267(-) (proC) [Campylobacter coli strain meC0281]
MKADLYILANGAMAQALAYGLKDSYNIYIVGRNLEKLQILEKEGFKTLLYKDFNIENKNIILAFKPYALESVAANLKGKA
KILISVLANTDFDKLKLIQAQNYARIMPNTAAKYKASTTPYVLKNSNFKDEVIEILNTFGKAYELNEEKQMNAAMAISGC
APAFLALVAESIANAGVYEGLSKELSLNLTRSLFKSAAALLENEHPAIIKENICSPAGVTIKGIKVLEQKGIRGTFFEAL
NASAT

Nucleotide

• Length: 738 bp

>NTDB_id=278548 DSM104626_RS03830 WP_002780246.1 745530..746267(-) (proC) [Campylobacter coli strain meC0281]
ATGAAAGCTGATTTATATATACTTGCTAATGGTGCGATGGCGCAAGCTTTGGCTTATGGATTAAAAGATTCTTATAATAT
CTATATAGTCGGTAGAAATTTAGAAAAGCTTCAAATTTTAGAAAAAGAAGGTTTTAAAACTTTACTCTATAAAGATTTTA
ATATAGAAAATAAAAATATTATCTTAGCTTTTAAACCTTATGCCTTAGAAAGTGTCGCAGCAAATTTAAAAGGCAAGGCA
AAAATTTTAATTTCAGTTTTAGCCAATACGGATTTTGATAAATTAAAACTTATCCAAGCCCAAAATTATGCAAGGATAAT
GCCAAATACAGCAGCTAAATATAAAGCTTCCACAACTCCTTATGTTTTAAAAAATTCAAATTTTAAAGATGAAGTCATAG
AAATTTTAAATACTTTTGGCAAAGCTTATGAGTTAAACGAAGAAAAACAAATGAATGCTGCCATGGCTATAAGCGGTTGC
GCTCCTGCTTTTTTAGCATTAGTAGCTGAAAGCATTGCTAATGCTGGCGTGTATGAAGGATTATCAAAAGAGCTGAGTTT
AAATCTCACTCGTTCGCTTTTTAAAAGTGCTGCAGCCTTGCTAGAAAACGAGCACCCAGCCATCATTAAGGAAAATATCT
GCTCGCCTGCAGGTGTTACCATAAAAGGGATTAAAGTATTAGAGCAAAAAGGTATCCGTGGGACTTTTTTTGAGGCTCTT
AATGCTAGTGCAACATGA

Domains

Predicted by InterproScan.

• NADP oxidoreductase coenzyme F420-dependent (F420_oxidored) (7-88)

• Pyrroline-5-carboxylate reductase dimerisation (P5CR_dimer) (148-244)

3D structure

• AlphaFold DB: A0A5T1L8T6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
proC	Campylobacter jejuni subsp. jejuni 81-176	80.833	97.959	0.792