Detailed information NTG0276236

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: D4H51_RS06620
• Genome accession: NZ_CP032480
• Coordinates: 1366922..1369504 (-)
• Length: 860 a.a.
• NCBI ID: WP_139544419.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain 19-C-EK1
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1361922..1374504

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D4H51_RS06600	-	1362770..1363968 (-)	1199	Protein_1268	DNA type IV secretion system protein ComB10	-
D4H51_RS06605	-	1363965..1365632 (-)	1668	WP_139544417.1	TrbG/VirB9 family P-type conjugative transfer protein	-
D4H51_RS06610	-	1365629..1366798 (-)	1170	WP_139544418.1	VirB8/TrbF family protein	-
D4H51_RS06615	-	1366791..1366925 (-)	135	WP_000738749.1	hypothetical protein	-
D4H51_RS06620	comB4	1366922..1369504 (-)	2583	WP_139544419.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
D4H51_RS06625	-	1369504..1369740 (-)	237	WP_139544420.1	hypothetical protein	-
D4H51_RS06630	comB3	1369751..1370014 (-)	264	WP_128036898.1	competence protein ComB	Machinery gene
D4H51_RS06635	comB2	1370026..1370310 (-)	285	WP_000736106.1	TrbC/VirB2 family protein	Machinery gene
D4H51_RS06640	-	1370307..1370786 (-)	480	WP_033749032.1	hypothetical protein	-
D4H51_RS06645	-	1370779..1371009 (-)	231	WP_000189076.1	hypothetical protein	-
D4H51_RS06650	-	1371012..1371800 (-)	789	WP_139544421.1	integrase	-
D4H51_RS06655	-	1371936..1372319 (+)	384	WP_120957918.1	hypothetical protein	-
D4H51_RS08435	-	1372711..1372878 (-)	168	WP_201737091.1	hypothetical protein	-
D4H51_RS06660	-	1372942..1373244 (-)	303	WP_139544422.1	hypothetical protein	-
D4H51_RS06665	-	1373264..1374256 (-)	993	WP_108169690.1	ketoacyl-ACP synthase III	-

Sequence

Protein

• Length: 860 a.a.
• Molecular weight: 98871.99 Da
• Isoelectric Point: 8.7977

>NTDB_id=276236 D4H51_RS06620 WP_139544419.1 1366922..1369504(-) (comB4) [Helicobacter pylori strain 19-C-EK1]
MLESTLKYCKEKTIDLLAGFVPKTYSMTEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFETITSNVKSFFEKKKLEMTTSISEELEES
SKEDKQENENSSNETHSNTSSKKDKKNKFKKKITFSTTSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNVHFKKDYFVIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDVIFHIRSLGQFESL
NFLKTKKKLTLSKIVKADIDNYIELVQANRLSMQECALNLVIRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYF
SFFPNNANINPRMRNQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGATGAGKTTLISYLMMSALKYSNIDILALDRLNGLYSFTKYFDGIYNQGENFHINPFSLEDSATNRAFLLHFYAQM
AKVDSYDKHNDKIEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNSIVKTNTNILDSSFEDYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDNDAGLLAYYVFHKMIDRALKINRGFLCFIDEFKSYAQNEMMNKEINKIITQARKANG
VIVLALQDINQLSEVKNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIENLIKHYPTTWKEVFVNNTYQKFDDKKHLEKVLCPT

Nucleotide

• Length: 2583 bp

>NTDB_id=276236 D4H51_RS06620 WP_139544419.1 1366922..1369504(-) (comB4) [Helicobacter pylori strain 19-C-EK1]
ATGTTAGAAAGCACCCTTAAATATTGCAAGGAAAAAACCATAGACCTTTTAGCAGGGTTTGTGCCAAAAACCTATTCTAT
GACAGAGGAATGCAATATTTTAGGCTTGTATGATGATACTTTCATCATCACTAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCAAACTTAATGCAAAAAGATTTGGAGGGCTATTTTGATACAAGGCAAAATGTTTTAAAC
ACCATTAGTAAAGACATTCAATTAAGGATTGTCGCTAAAAGGCGTAAAGAATTTATCAACCAAAGCCCAAATATTGATAA
CCCATACGCAAAAGCCATTATCACGCAATTTGAAAGCAAGGAAATCTATAAAACAGAGTATTTTTTAGTGTTTGAAACTA
TCACTTCTAATGTCAAGTCTTTCTTTGAAAAAAAGAAATTGGAAATGACTACTTCAATTAGTGAAGAGTTAGAAGAAAGC
TCTAAAGAAGATAAACAAGAGAATGAAAATAGCTCCAATGAAACTCATTCAAACACAAGCTCTAAAAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGATAACCTTTAGCACCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTAAAAAACG
CATTAAGGGAGTTTAAACCCACTCTTTTAAATTCTAAAGAAGTGTTGAATTTTTATGCAGAATATATCAATGGCAAATAT
ATCGCCTTTAATCCTAAATTAAAGCGATTAAGCGATAGCTATATTGCATCTAATGTGCATTTTAAGAAAGATTACTTTGT
CATTGAATTTCAAAATCAAAGCACTTTTTGTGCGTGTGTGGGGATTAAAAACTATGAGAGTGAAGAAATTTCTTCACTCC
CCATTTCTACCCTTTTACACACCCAAATTGAATTAGATGTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGCCTG
AATTTTTTAAAAACTAAGAAAAAGCTCACGCTTTCTAAAATAGTAAAAGCTGATATTGATAATTATATAGAATTAGTGCA
AGCCAATCGTTTGAGCATGCAAGAGTGTGCTTTAAACTTAGTTATAAGGGCTAAAAGTAAAGCTAAATTAGACAAGTCTT
TAAAAGAGATTTTATCCTTGCTTAATAATGCTGGACTAGGCAGTGTTACAGAAACTATAGGGCTAAAACCATCTTATTTT
TCATTCTTCCCAAATAACGCCAATATCAATCCTAGAATGAGAAATCAAACTTCCCAAGTGATTGCCTCTTTAATCTTGTT
TGAGAAAAATAATACAGGTTTTAGGGCAAATTCATGGGGGGATATGCCCTTATCTGTGTTTAAGAACCTAGACCATAGCC
CTTATTTGTTTAATTTTCATAATCAAGAAGTCAAACATAAGGGCGTGTTAGCCCACAATGTCGCACGAGTAGTGGGACAT
ACCATGATTATAGGAGCAACAGGTGCTGGTAAAACCACACTCATTAGCTATTTGATGATGAGTGCTTTAAAATATTCTAA
CATTGATATTTTAGCTCTTGATAGACTAAATGGTTTGTATTCCTTTACCAAGTATTTTGATGGGATTTATAATCAAGGCG
AAAACTTTCATATTAACCCTTTTTCATTAGAAGATAGCGCAACTAATAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTAGATAGCTATGACAAACATAATGATAAGATAGAAGATAGAACAGCTCTTTTAAACGCTATTGATACCATGTA
TAGAAATTATAACGATGAAGTCAAACAAGCCAAATTCAGCAACCAAGAATTACCACTTCCTTTTGATTTAAAAGAGTTTG
TCAATTCCATTGTTAAAACCAATACAAACATTTTAGATAGCAGTTTTGAAGACTATTTAAAATCTTCCTTATTTTCTAGC
CGAATGGATAGCCTAGATTTTAAAACTCGTATTAGCACCATAAATACTGATAGCATTTTACACAATGATAATGACGCTGG
GCTTTTAGCTTATTATGTGTTTCATAAGATGATTGATAGAGCTTTGAAAATCAATCGTGGGTTTTTATGTTTTATTGATG
AGTTTAAATCTTACGCTCAAAATGAAATGATGAATAAAGAAATCAATAAAATCATCACGCAAGCTAGAAAGGCTAATGGG
GTCATTGTTCTAGCCTTACAAGATATTAACCAACTTAGTGAAGTGAAAAACGCTCAAAGCTTTATTAAAAATATGGGGCA
ATTAATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTAAGTTCTTTGGGTAATTACTTACAAATCTTTAGCTCCAATTCTAGCATGGTAGAACACATTGAAAATCT
TATTAAGCATTACCCTACTACTTGGAAAGAAGTCTTTGTCAATAACACCTATCAAAAATTTGATGACAAAAAACACTTAG
AAAAGGTGCTTTGCCCAACATGA

Domains

Predicted by InterProScan.

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (437-505)

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	46.73	97.791	0.457