Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   C2840_RS00220 Genome accession   NZ_CP026326
Coordinates   37674..38411 (+) Length   245 a.a.
NCBI ID   WP_000660509.1    Uniprot ID   A0AAC8N035
Organism   Helicobacter pylori strain 26695-dR     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 32674..43411
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2840_RS00195 (C2840_00195) panD 34831..35184 (+) 354 WP_000142250.1 aspartate 1-decarboxylase -
  C2840_RS00200 (C2840_00200) - 35187..35480 (+) 294 WP_000347915.1 YbaB/EbfC family nucleoid-associated protein -
  C2840_RS00205 (C2840_00205) - 35480..36484 (+) 1005 WP_000468475.1 PDZ domain-containing protein -
  C2840_RS00210 (C2840_00210) comB6 36492..37547 (+) 1056 WP_000786660.1 P-type conjugative transfer protein TrbL Machinery gene
  C2840_RS08340 (C2840_00215) - 37563..37677 (+) 115 Protein_33 comB7 lipoprotein -
  C2840_RS00220 (C2840_00220) comB8 37674..38411 (+) 738 WP_000660509.1 type IV secretion system protein Machinery gene
  C2840_RS00225 (C2840_00225) comB9 38411..39388 (+) 978 WP_001862530.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  C2840_RS00230 (C2840_00230) comB10 39381..40517 (+) 1137 WP_001045839.1 DNA type IV secretion system protein ComB10 Machinery gene
  C2840_RS00235 (C2840_00235) - 40587..41999 (+) 1413 WP_000694809.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  C2840_RS00240 (C2840_00240) gmd 42041..43186 (+) 1146 WP_000659810.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28567.79 Da        Isoelectric Point: 8.9546

>NTDB_id=268203 C2840_RS00220 WP_000660509.1 37674..38411(+) (comB8) [Helicobacter pylori strain 26695-dR]
MKEKPFNSEQLIYLEELLNHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
VQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
TNRGD

Nucleotide


Download         Length: 738 bp        

>NTDB_id=268203 C2840_RS00220 WP_000660509.1 37674..38411(+) (comB8) [Helicobacter pylori strain 26695-dR]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAGTTGATCTATTTAGAAGAGCTTTTAAACCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTCAGACTGGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTGTTAATCAGTGTTCTGCCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAATCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGTATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GTGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCCATTGCGGCTAAACTTTTGAACGAAAACAAGTTGGTGTATGAAAAGCGTTATAAAATCGTATTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGATTTAAAATCACCCGTTACAGCATCACTGAAATC
ACTAATAGGGGTGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.166

100

0.98

Multiple sequence alignment