Detailed information NTG0266281

Bioinformatically predicted

Overview

• Name: recD2
• Type: Machinery gene
• Locus tag: RK72_RS12975
• Genome accession: NZ_CP026063
• Coordinates: 2504673..2507150 (-)
• Length: 825 a.a.
• NCBI ID: WP_001283312.1
• Uniprot ID: A0A7U7EYY0
• Organism: Staphylococcus aureus strain FDAARGOS_14
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2499673..2512150

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RK72_RS12950 (RK72_012950)	-	2499699..2500337 (-)	639	WP_000342258.1	O-methyltransferase	-
RK72_RS12955 (RK72_012955)	-	2500622..2500930 (-)	309	WP_000134779.1	DUF1292 domain-containing protein	-
RK72_RS12960 (RK72_012960)	ruvX	2500945..2501373 (-)	429	WP_000939059.1	Holliday junction resolvase RuvX	-
RK72_RS12965 (RK72_012965)	-	2501377..2501637 (-)	261	WP_000426912.1	IreB family regulatory phosphoprotein	-
RK72_RS12970 (RK72_012970)	alaS	2501700..2504330 (-)	2631	WP_000734075.1	alanine--tRNA ligase	-
RK72_RS12975 (RK72_012975)	recD2	2504673..2507150 (-)	2478	WP_001283312.1	ATP-dependent RecD-like DNA helicase	Machinery gene
RK72_RS12980 (RK72_012980)	-	2507152..2507820 (-)	669	WP_000567017.1	tetratricopeptide repeat protein	-
RK72_RS12985 (RK72_012985)	mnmA	2508459..2509577 (-)	1119	WP_000066097.1	tRNA 2-thiouridine(34) synthase MnmA	-
RK72_RS12990 (RK72_012990)	-	2509578..2510720 (-)	1143	WP_000409157.1	cysteine desulfurase family protein	-
RK72_RS12995 (RK72_012995)	-	2511032..2512045 (+)	1014	WP_000985878.1	LLM class flavin-dependent oxidoreductase	-

Sequence

Protein

• Length: 825 a.a.
• Molecular weight: 92958.74 Da
• Isoelectric Point: 4.4945

>NTDB_id=266281 RK72_RS12975 WP_001283312.1 2504673..2507150(-) (recD2) [Staphylococcus aureus strain FDAARGOS_14]
MSDPTLFDYSMIKGTVEAILFQNSDNFYTVLKVDTIETNEDFDTMPTVVGFLPNIVEGDVYTFKGQVVDHPRYGKQLKAE
TFEKEMPQTKEAIISYLSSDLFKGVGKKTAQNIVNTLGDNAINDILDDHSVLEKVSGLSKKKQKQIAEQISANQESEKIM
IRLHDLGFGPKLSMAIYQFYLGDTLTILDRNPYQLIYDIKGIGFNKADQLARNIGIAYNDNERLKAALLYTLEEECIKQG
HTYLPINVVIDLTVDVLNYQDEEVIEPEKLDEMLQYLNEEKRLIIDNEQVAIPSLYYSEIKSVQNLFRIKTHTNKLTEIE
QSDLQMHIGEIEDANQVNYAASQKEALQTAINSKVMLLTGGPGTGKTTVIKGIVELYAEIHGLSLDYDDYVNDDYPVVLA
APTGRASKRLQESTGLEAMTIHRLIGWNQDTKPEDILENEINARLIIIDEMSMVDTWLFHQFLSAVPLDAQLIFVGDEDQ
LPSVGPGQVFKDLIESKAIPRVNLTEVYRQQDGSSIIELAHRMKLGQKIDITQRFHDRSFINCQANQIPTVVEKVVTSAV
NKGYTMADIQVLAPMYKGNAGIKRLNQVLQDILNPKKKDTREIEFGDVVFRKGDKVLQLVNRPNDNIFNGDIGVIVGIFW
AKENALNKDVLVVDFEGNEITFTKQDMMELTHAYCTSIHKSQGSEFPIVIMPIVKQYFRMLQRPILYTGLTRAKTSLVLL
GDPEAFDIGLKTNGQARLTQLCTLLKNYFNSEDEEMLENTATNDTGASQTTIDDQVEAPMSSNDSGEVTSDSTKTDINVL
TEATMFKIDPMINMGEITPYDFIER

Nucleotide

• Length: 2478 bp

>NTDB_id=266281 RK72_RS12975 WP_001283312.1 2504673..2507150(-) (recD2) [Staphylococcus aureus strain FDAARGOS_14]
ATGTCAGACCCTACACTATTTGATTATTCAATGATCAAAGGTACTGTTGAAGCGATATTGTTTCAAAACAGTGATAATTT
TTATACAGTGCTTAAAGTAGATACTATTGAAACAAATGAAGACTTTGATACAATGCCAACTGTTGTAGGGTTTCTTCCGA
ATATTGTTGAAGGCGATGTCTACACATTTAAAGGGCAAGTTGTTGATCATCCACGTTATGGTAAACAATTAAAAGCAGAG
ACTTTTGAAAAAGAAATGCCACAAACGAAAGAAGCAATTATAAGTTATTTATCTAGTGATTTGTTTAAAGGTGTAGGTAA
AAAGACAGCTCAAAATATTGTTAATACATTAGGTGACAATGCGATAAATGATATATTAGATGACCATTCAGTGCTAGAAA
AAGTTTCGGGATTATCTAAAAAGAAACAGAAACAAATTGCAGAACAAATTTCAGCAAATCAAGAATCTGAAAAAATAATG
ATTCGTTTACATGATTTAGGGTTTGGTCCTAAACTTTCAATGGCAATTTATCAGTTTTATCTCGGCGATACACTGACTAT
TTTAGATCGAAATCCATATCAATTGATTTATGATATTAAAGGTATTGGTTTTAATAAAGCAGATCAACTTGCTAGAAATA
TTGGTATCGCTTATAACGATAATGAACGATTAAAAGCTGCGTTGCTCTATACGTTAGAAGAAGAATGTATTAAACAGGGA
CATACATATTTGCCTATCAATGTTGTTATAGATTTAACGGTTGATGTATTAAATTATCAAGATGAAGAGGTCATCGAACC
TGAAAAATTAGACGAAATGTTGCAATACTTAAATGAGGAAAAACGACTAATTATTGACAATGAACAAGTTGCAATTCCAA
GTTTGTATTATTCTGAAATCAAAAGTGTTCAAAACTTATTCAGAATAAAGACGCATACAAATAAACTTACGGAAATTGAA
CAGTCAGATTTACAAATGCATATTGGTGAAATAGAAGATGCGAATCAAGTGAACTATGCAGCTTCACAAAAAGAAGCTTT
GCAAACGGCTATCAATTCTAAGGTGATGCTATTAACCGGTGGACCGGGAACAGGAAAGACGACAGTAATTAAAGGTATTG
TAGAATTATATGCTGAGATTCATGGCTTATCATTAGATTATGATGATTATGTCAATGATGATTATCCAGTTGTATTAGCA
GCGCCAACAGGAAGAGCGTCTAAGAGACTACAAGAGTCAACTGGATTAGAAGCAATGACGATTCATCGTTTAATAGGTTG
GAATCAAGACACAAAGCCAGAGGATATATTAGAAAATGAAATAAACGCACGACTCATAATCATTGATGAGATGTCTATGG
TAGATACTTGGTTGTTTCACCAATTTTTAAGTGCAGTTCCTTTAGATGCACAATTGATATTTGTAGGTGATGAGGACCAA
TTGCCTTCTGTAGGTCCTGGTCAAGTATTTAAAGATTTAATTGAATCGAAAGCTATACCACGAGTTAATCTGACTGAAGT
ATATCGTCAACAAGATGGTTCAAGCATTATAGAATTAGCACATCGAATGAAATTGGGTCAGAAAATTGATATTACACAGC
GTTTTCATGATAGAAGTTTTATTAACTGTCAGGCAAACCAAATACCAACAGTTGTTGAGAAGGTAGTTACTAGTGCTGTT
AATAAAGGGTATACTATGGCTGATATTCAAGTGCTTGCACCAATGTATAAAGGAAATGCCGGTATTAAACGTTTAAATCA
AGTTTTACAAGATATTTTAAACCCTAAAAAGAAAGACACACGAGAAATTGAGTTTGGTGATGTAGTCTTTAGAAAAGGTG
ACAAAGTATTACAACTTGTTAATAGGCCAAATGATAACATATTCAATGGTGACATAGGAGTTATTGTTGGTATTTTTTGG
GCGAAAGAAAATGCCCTTAATAAAGATGTACTTGTTGTGGATTTTGAAGGTAATGAAATTACATTTACGAAACAAGATAT
GATGGAATTAACACATGCTTATTGTACATCAATCCATAAATCACAAGGTTCAGAATTTCCTATTGTTATCATGCCTATTG
TTAAACAGTATTTTAGAATGTTACAAAGACCGATATTATATACTGGTTTAACTAGAGCGAAAACGAGTTTAGTTCTACTT
GGTGATCCAGAAGCATTTGATATTGGATTAAAAACAAATGGTCAAGCGCGTTTAACACAATTATGTACATTGTTGAAAAA
TTATTTTAATTCAGAAGATGAAGAAATGCTGGAAAACACAGCAACTAATGATACAGGAGCTTCACAAACGACAATAGATG
ATCAAGTAGAAGCGCCAATGTCATCGAATGATAGTGGAGAAGTTACGTCTGATTCAACAAAAACAGATATAAATGTATTA
ACGGAAGCTACAATGTTTAAAATTGACCCAATGATTAATATGGGAGAAATCACGCCGTATGACTTTATAGAACGTTGA

Domains

Predicted by InterproScan.

• ATP-dependent RecD-like DNA helicase SH3 domain (SH3_13) (585-655)

• AAA domain (AAA_30) (339-544)

• UvrD-like helicase C-terminal domain (UvrD_C_2) (672-720)

• Helix-hairpin-helix containing domain (HHH_RecD2) (153-243)

3D structure

• AlphaFold DB: A0A7U7EYY0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
recD2	Bacillus subtilis subsp. subtilis str. 168	52.988	91.273	0.484