Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   SPYM_RS01885 Genome accession   NC_009332
Coordinates   371038..371820 (+) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes str. Manfredo     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 366038..376820
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYM_RS01865 (SpyM50329) - 366375..367340 (-) 966 WP_002983258.1 asparaginase -
  SPYM_RS01870 (SpyM50330) - 367412..368800 (+) 1389 WP_011888631.1 Cof-type HAD-IIB family hydrolase -
  SPYM_RS01875 (SpyM50331) - 368923..369375 (-) 453 WP_002992571.1 universal stress protein -
  SPYM_RS01880 (SpyM50332) - 369606..370820 (+) 1215 WP_011184883.1 pyridoxal phosphate-dependent aminotransferase -
  SPYM_RS01885 (SpyM50333) codY 371038..371820 (+) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  SPYM_RS01890 (SpyM50334) - 371967..372521 (+) 555 WP_002988559.1 cysteine hydrolase family protein -
  SPYM_RS01895 (SpyM50335) - 373059..373283 (+) 225 WP_014635660.1 putative PEP-binding protein -
  SPYM_RS01900 (SpyM50337) gatC 373515..373817 (+) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  SPYM_RS01905 (SpyM50338) gatA 373817..375283 (+) 1467 WP_011888632.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  SPYM_RS01910 (SpyM50339) gatB 375283..376722 (+) 1440 WP_011888633.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=26461 SPYM_RS01885 WP_002983278.1 371038..371820(+) (codY) [Streptococcus pyogenes str. Manfredo]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=26461 SPYM_RS01885 WP_002983278.1 371038..371820(+) (codY) [Streptococcus pyogenes str. Manfredo]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAATTTAGTGATGATGATTTGATCTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504

Multiple sequence alignment