Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   SPYM_RS01665 Genome accession   NC_009332
Coordinates   316454..318793 (+) Length   779 a.a.
NCBI ID   WP_011888615.1    Uniprot ID   A2RCQ8
Organism   Streptococcus pyogenes str. Manfredo     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 311454..323793
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYM_RS01645 (SpyM50285) lepB 313786..314379 (-) 594 WP_002983074.1 signal peptidase I -
  SPYM_RS01650 (SpyM50286) rnhC 314390..315292 (-) 903 WP_011888614.1 ribonuclease HIII -
  SPYM_RS01655 (SpyM50287) - 315449..315757 (+) 309 WP_002993251.1 hypothetical protein -
  SPYM_RS01660 (SpyM50288) - 315760..316305 (+) 546 WP_002983087.1 CvpA family protein -
  SPYM_RS01665 (SpyM50289) mutS/mutS2 316454..318793 (+) 2340 WP_011888615.1 endonuclease MutS2 Machinery gene
  SPYM_RS01670 (SpyM50290) - 318797..319297 (+) 501 WP_011018191.1 phosphatase PAP2 family protein -
  SPYM_RS01675 (SpyM50291) trxA 319360..319692 (+) 333 WP_256363924.1 thioredoxin -
  SPYM_RS01680 (SpyM50292) - 319744..320331 (-) 588 WP_011018189.1 helix-turn-helix domain-containing protein -
  SPYM_RS01685 (SpyM50293) mutY 320508..321662 (-) 1155 WP_162009222.1 A/G-specific adenine glycosylase -
  SPYM_RS01690 (SpyM50294) - 321830..322123 (+) 294 WP_002983113.1 hypothetical protein -
  SPYM_RS01695 (SpyM50295) rpsF 322296..322586 (+) 291 WP_002983117.1 30S ribosomal protein S6 -
  SPYM_RS01700 (SpyM50296) ssbA 322608..323099 (+) 492 WP_002993238.1 single-stranded DNA-binding protein Machinery gene
  SPYM_RS01705 (SpyM50297) rpsR 323264..323503 (+) 240 WP_002983142.1 30S ribosomal protein S18 -

Sequence

Protein


Download         Length: 779 a.a.        Molecular weight: 87840.03 Da        Isoelectric Point: 6.5465

>NTDB_id=26456 SPYM_RS01665 WP_011888615.1 316454..318793(+) (mutS/mutS2) [Streptococcus pyogenes str. Manfredo]
MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEASKIEKSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLEL
SADLNIQELLAIKKVLQSSSDMIHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTVYIEPRAVVTLNEEITQLRADER
HEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRAKYLFMSDNKATIPKISNDSTLALINVRHPLLSNPVANDLHFDHD
LTAIVITGPNTGGKTIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHIVSILNEAD
HNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYGIETNFVENASMEFDAETLSPTYRFMQGVPG
RSNAFEIASRLGLAPFIVKQAKQMTDSDSDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKE
LEKIYQEAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKKIKAARAPRIGDDIIVT
SYGQRGTLTSQLKDGRWEAQVGIIKMTLTHDEFTLVRVQEEQKVKNKQINVVKKADSSGPRARLDLRGKRYEEAMQELDH
FIDQALLNNMGQVDIIHGIGTGVIREGVTKYLRRHKHVKHFAYAPQNAGGSGATIVTLG

Nucleotide


Download         Length: 2340 bp        

>NTDB_id=26456 SPYM_RS01665 WP_011888615.1 316454..318793(+) (mutS/mutS2) [Streptococcus pyogenes str. Manfredo]
ATGAATAACAAGATTTTAGAGCAGTTAGAATTTAACAAAGTTAAGGAATTGCTATTACCTTATCTCAAGACAGAACAATC
CCAAGAAGAATTATTAGAGCTGGAGCCGATGACGGAGGCTTCTAAAATAGAAAAAAGTTTTAATGAAATTTCTGACATGG
AACAGATTTTTGTTGAACATCACTCATTTGGCATAGTCAGCCTAAGTTCAATCTCTGAGAGTTTAAAACGTTTAGAACTT
TCAGCTGATCTTAATATTCAAGAACTTTTGGCTATCAAAAAAGTTTTACAGAGTTCTTCGGATATGATTCACTTTTATTC
TGATTTGGATAATGTTTCTTTCCAATCTTTGGATCGTTTGTTTGAAAATTTGGAACAATTCCCTAATCTGCAAGGGTCTT
TTCAAGCTATCAATGATGGTGGTTTTTTAGAACATTTTGCGAGTCCAGAATTAGAGCGTATCCGTCGTCAATTAACAAAT
AGTGAACGACGGGTTCGTCAGATTTTACAGGATATGCTTAAGGAAAAAGCAGAGCTTTTATCAGAAAATCTAATCGCTAG
TCGTAGTGGACGAAGTGTCCTACCAGTAAAAAATACTTATCGGAATCGTATTTCTGGTGTGGTTCATGACATCTCTTCTT
CAGGAAGTACTGTTTATATTGAGCCTCGTGCTGTAGTTACACTAAACGAAGAGATAACGCAGCTTAGAGCTGACGAACGC
CACGAAGAAGGTCGTATTTTACACGCATTTTCAGACTTGTTAAGACCTCATGTCGCCACTATTAGAAATAATGCATGGAT
TCTTGGGCATCTTGATTTTGTAAGGGCTAAATATCTTTTTATGTCTGATAATAAGGCGACGATACCTAAGATTTCTAATG
ACAGCACGTTAGCATTAATCAATGTTCGTCATCCTCTTTTAAGTAATCCTGTGGCTAATGACTTACATTTTGATCACGAT
TTAACTGCAATTGTCATTACTGGTCCCAATACTGGTGGTAAGACGATTATGCTAAAAACACTCGGTTTAGCACAATTAAT
GGGACAGTCTGGTTTGCCAGTATTAGCGGATAAAGGTAGTAAAATTGCAGTATTTAACAATATCTTTGCAGATATTGGCG
ATGAGCAATCTATTGAACAAAGTCTATCAACTTTTTCTAGTCATATGACGCACATAGTCAGTATTTTAAACGAGGCTGAC
CACAATAGTTTAGTTCTCTTTGATGAACTAGGAGCAGGAACGGATCCTCAAGAAGGTGCTAGTTTGGCCATGGCTATTTT
AGAACACCTTAGGTTAAGTCATATCAAAACGATGGCGACCACGCACTATCCAGAATTAAAAGCTTATGGGATTGAGACAA
ATTTTGTAGAGAATGCGAGCATGGAATTTGATGCAGAAACGCTTAGCCCCACATATCGCTTTATGCAAGGAGTTCCTGGA
CGCTCAAATGCATTTGAAATTGCTTCTCGCCTTGGTTTAGCTCCATTTATTGTTAAACAAGCTAAGCAGATGACAGATTC
TGACTCAGATGTTAACCGTATTATTGAACAGTTAGAGGCACAGACACTTGAGACACGTAGAAGACTGGATCATATTAAAG
AAGTTGAACAAGAAAACCTCAAATTCAATCGTGCGGTTAAGAAACTCTATAATGAATTTTCACATGAACGCGATAAAGAG
TTAGAAAAAATCTATCAAGAAGCTCAAGAAATTGTAGATATGGCTTTGAATGAGAGTGATACTATCTTAAAAAAACTCAA
TGATAAGAGTCAATTAAAACCTCACGAAATTATAGATGCTAAGGCACAAATAAAAAAATTAGCGCCTCAAGTTGATTTAT
CAAAAAATAAAGTCTTAAATAAGGCTAAAAAAATCAAAGCAGCTCGTGCCCCTAGAATTGGTGATGATATTATAGTGACT
AGCTATGGACAGCGAGGTACCTTAACTAGTCAATTAAAAGATGGCCGTTGGGAAGCACAAGTGGGAATTATCAAAATGAC
ATTAACACATGATGAATTTACCCTCGTTAGAGTCCAAGAAGAACAAAAAGTCAAAAATAAACAGATTAATGTGGTTAAAA
AGGCTGATAGTTCTGGACCAAGAGCTCGACTTGATCTTAGAGGTAAAAGATACGAAGAAGCTATGCAAGAGTTAGATCAT
TTTATTGATCAAGCATTGCTTAACAATATGGGACAAGTTGATATCATTCATGGGATTGGTACAGGCGTTATCCGTGAGGG
AGTGACAAAATATCTTCGTCGTCATAAGCATGTTAAGCATTTTGCTTATGCCCCACAAAATGCAGGGGGATCTGGCGCCA
CAATTGTAACGTTAGGGTAA

Domains

Predicted by InterProScan.

Smr domain (Smr)

(704-778)

MutS2 and Smr-associated SH3 domain (MSSS)

(633-668)

MutS domain V (MutS_V)

(324-505)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCQ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

40.633

100

0.412

Multiple sequence alignment