Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   DV129_RS00015 Genome accession   NZ_CP031247
Coordinates   406..1194 (+) Length   262 a.a.
NCBI ID   WP_000940733.1    Uniprot ID   C1CSK2
Organism   Streptococcus pneumoniae strain M23734     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1..6194
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV129_RS00015 codY 406..1194 (+) 789 WP_000940733.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  DV129_RS00020 - 1194..1769 (+) 576 WP_000158725.1 isochorismatase family cysteine hydrolase -
  DV129_RS00030 ugpC 2219..3349 (+) 1131 WP_000229959.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -
  DV129_RS11615 - 3496..3642 (-) 147 WP_001846606.1 hypothetical protein -
  DV129_RS00035 - 3850..4608 (+) 759 WP_001287230.1 class I SAM-dependent methyltransferase -
  DV129_RS00040 - 4695..5207 (+) 513 WP_001049323.1 adenine phosphoribosyltransferase -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 29756.15 Da        Isoelectric Point: 5.7806

>NTDB_id=263209 DV129_RS00015 WP_000940733.1 406..1194(+) (codY) [Streptococcus pneumoniae strain M23734]
MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNACIINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYV
QGANMIYETEANLPVEHDMSIFPVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLISDIFEEVKKRDY

Nucleotide


Download         Length: 789 bp        

>NTDB_id=263209 DV129_RS00015 WP_000940733.1 406..1194(+) (codY) [Streptococcus pneumoniae strain M23734]
ATGGCACATTTATTAGAAAAAACTAGAAAAATTACATCAATTTTGAAACGCTCAGAGGAGCAGTTGCAGGATGAGCTTCC
TTACAACGCTATTACGCGTCAGTTAGCGGATATTATTCATTGCAATGCCTGCATTATCAATAGTAAGGGACGTCTGCTTG
GCTATTTTATGCGTTATAAAACAAATACAGATCGCGTAGAGCAATTCTTCCAAACTAAGATTTTCCCAGATGACTACGTT
CAAGGGGCTAATATGATTTACGAAACAGAAGCAAACTTACCTGTTGAGCATGATATGAGTATTTTCCCTGTTGAGAGTAG
AGATGATTTTCCAGATGGCTTGACGACTATTGCACCGATTCATGTATCGGGGATTCGCCTTGGTTCTTTGATTATTTGGC
GTAATGATAAAAAATTCGAAGATGAGGACTTGGTTCTTGTTGAGATTGCCAGTACCGTTGTTGGGATTCAGCTTCTTAAC
TTCCAACGTGAAGAAGATGAGAAAAATATTCGTCGTCGTACTGCTGTCACCATGGCGGTCAATACCCTTTCTTACTCCGA
ACTCCGTGCTGTTTCAGCAATTTTAGGGGAATTAAATGGAAATGAAGGGAAGTTGACTGCGTCAGTGATTGCAGATCGTA
TCGGAATCACTCGCTCTGTGATTGTCAATGCTCTTCGTAAACTTGAGTCTGCGGGGATTATTGAAAGTCGCTCACTTGGA
ATGAAGGGAACCTATCTTAAGGTCTTGATTTCAGATATTTTTGAAGAAGTGAAGAAAAGAGATTACTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-258)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C1CSK2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

62.595

100

0.626
  codY Bacillus subtilis subsp. subtilis str. 168

48.374

93.893

0.454