Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   SSA_RS01890 Genome accession   NC_009009
Coordinates   346987..349320 (+) Length   777 a.a.
NCBI ID   WP_011836455.1    Uniprot ID   A3CKV4
Organism   Streptococcus sanguinis SK36     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 341987..354320
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSA_RS01870 (SSA_0351) lepB 344368..344997 (-) 630 WP_011836453.1 signal peptidase I -
  SSA_RS01875 (SSA_0352) rnhC 345001..345891 (-) 891 WP_033179112.1 ribonuclease HIII -
  SSA_RS01880 (SSA_0353) - 346080..346370 (+) 291 WP_002896593.1 hypothetical protein -
  SSA_RS01885 (SSA_0354) - 346381..346932 (+) 552 WP_002896592.1 CvpA family protein -
  SSA_RS01890 (SSA_0355) mutS/mutS2 346987..349320 (+) 2334 WP_011836455.1 endonuclease MutS2 Machinery gene
  SSA_RS01895 (SSA_0356) - 349399..350817 (+) 1419 WP_011836456.1 C69 family dipeptidase -
  SSA_RS01900 (SSA_0357) trxA 350903..351217 (+) 315 WP_002903373.1 thioredoxin -
  SSA_RS01905 (SSA_0358) - 351378..351887 (-) 510 WP_011836457.1 DUF4865 family protein -
  SSA_RS01910 - 351996..352743 (+) 748 Protein_341 LysR family transcriptional regulator -
  SSA_RS01915 (SSA_0360) - 352844..353251 (+) 408 WP_011836459.1 polyketide cyclase -
  SSA_RS01920 (SSA_0362) trxA 353341..353654 (+) 314 Protein_343 thioredoxin -

Sequence

Protein


Download         Length: 777 a.a.        Molecular weight: 87397.64 Da        Isoelectric Point: 5.3148

>NTDB_id=26259 SSA_RS01890 WP_011836455.1 346987..349320(+) (mutS/mutS2) [Streptococcus sanguinis SK36]
MNTKILETLEFSKIKELFAPYLLTEQGQLELGLLLPTSKKETVVSAFLEMTDMQQIFVQHPHFSLAATQDITALTKRLEL
ESDLNIEEFLALKRVLAVTQELKSFYEDLENVHLEKLDRLFDNLAVFPKLQGSLQAVNDGGFIESFASESLSRIRRKIQE
NENQVREILQEILKNKGEMLADQVVASRNGRNVLPVKNTYRNRISGVVHDISASGNTVYIEPRAVVNLNEEIASSRADER
YEIQRILQELSDLFRPHAAEIANNAWIIGHLDLVRAKVRFMQETGAVVPDLSEEQDIQLLSVRHPLIENAVANDLHFGLD
LTEIVITGPNTGGKTIMLKTLGLAQIMAQSGLPILADKGSRVGIFSQIFADIGDEQSIEQSLSTFSSHMTNIVSILEQVD
SESLVLLDELGAGTDPQEGAALAIAILEDLRLRQIKTMATTHYPELKAYGIETDWVENASMEFDTDSLRPTYRFMQGVPG
RSNAFEIAQRLGLSEVIVGHAQEQTDTDSDVNRIIERLEEQTLESRKRLDNIREVEQENLKFNRALKKLYNEFNREKETE
LNKARLEAQEIVDLALSESESILKNLHDKSSLKPHEIIEAKAQLKKLAPETVDLSKNKVLKQAKKNRAPKVGDDILVTSY
GQRGTLVKQLKDGRWEAQVGLIKMTLEEQEFNLLKAEKEQQPKRKQVNVVKRANTAGPKARLDLRGKRYEEAMEELDAFI
DQALLNNMAQVDIIHGIGTGVIREGVTKYLRRNKHVKSFGYAPQNAGGSGATIVIFK

Nucleotide


Download         Length: 2334 bp        

>NTDB_id=26259 SSA_RS01890 WP_011836455.1 346987..349320(+) (mutS/mutS2) [Streptococcus sanguinis SK36]
ATGAACACAAAAATTTTAGAAACCTTAGAATTTAGCAAGATAAAAGAACTTTTTGCTCCCTATCTTTTGACCGAGCAGGG
GCAGCTGGAGCTGGGCCTGCTTTTGCCGACTAGCAAGAAGGAGACGGTGGTCTCGGCTTTTCTGGAAATGACGGATATGC
AGCAGATTTTTGTGCAGCATCCGCACTTTAGTCTGGCAGCGACTCAGGATATTACTGCCTTGACCAAGCGCTTGGAGCTG
GAAAGCGACTTGAATATTGAGGAGTTTTTGGCCCTCAAACGAGTCTTGGCTGTGACTCAGGAGCTCAAGTCCTTTTATGA
GGACTTGGAAAATGTGCACTTGGAAAAGCTGGACCGTCTGTTTGATAATCTAGCTGTTTTCCCTAAACTGCAAGGAAGTC
TGCAGGCTGTTAATGATGGCGGCTTTATTGAAAGCTTTGCCAGCGAAAGTTTGAGCCGCATCCGCCGAAAAATTCAAGAA
AATGAAAACCAGGTGCGGGAAATTTTGCAGGAAATTCTCAAAAACAAGGGAGAGATGCTGGCGGATCAGGTAGTGGCCAG
CCGGAATGGCCGCAATGTGCTGCCCGTGAAAAATACCTACCGCAACCGCATTTCAGGTGTGGTTCACGATATTTCTGCCA
GCGGCAATACCGTCTATATCGAGCCTAGAGCAGTTGTCAATCTCAACGAAGAAATTGCCAGCAGTCGGGCGGACGAACGT
TATGAAATTCAGCGGATTTTGCAAGAATTATCGGATCTCTTCCGTCCCCATGCAGCTGAAATTGCCAACAATGCTTGGAT
TATCGGACATCTGGACCTGGTGCGTGCCAAGGTCCGCTTCATGCAGGAGACGGGAGCGGTGGTGCCAGACCTGTCGGAGG
AGCAGGATATCCAACTGCTCAGTGTCCGCCATCCCCTGATTGAAAATGCAGTGGCTAATGATTTGCATTTCGGGCTAGAC
TTGACAGAGATTGTCATTACCGGGCCTAATACCGGTGGTAAGACCATCATGCTGAAGACCTTGGGCTTGGCTCAGATCAT
GGCCCAGTCAGGTCTGCCGATTCTGGCGGACAAGGGGAGTCGCGTCGGGATTTTCAGTCAGATTTTTGCAGACATTGGTG
ATGAGCAGTCCATTGAGCAGAGCCTGTCGACTTTCTCCAGTCACATGACCAATATCGTCTCTATTTTAGAGCAGGTTGAT
AGCGAGAGTTTGGTCCTGCTGGATGAGCTGGGAGCTGGGACTGACCCGCAGGAGGGTGCAGCTCTGGCTATTGCTATCTT
GGAAGATTTGCGGCTAAGGCAGATTAAAACCATGGCAACGACCCATTATCCTGAGCTCAAAGCCTATGGGATTGAGACGG
ACTGGGTGGAAAATGCCAGCATGGAATTTGATACAGATAGTTTAAGGCCGACCTATCGCTTTATGCAGGGAGTGCCTGGT
CGCTCCAATGCCTTTGAAATCGCTCAGCGTTTGGGTTTGTCGGAAGTTATCGTTGGCCATGCCCAAGAGCAGACTGACAC
AGACAGCGATGTCAATCGGATTATTGAGCGCTTAGAGGAGCAGACACTGGAAAGCCGCAAGCGCTTGGATAATATCCGCG
AGGTGGAGCAGGAAAATCTCAAATTTAACCGAGCCCTCAAAAAACTTTACAATGAGTTTAACCGAGAAAAGGAAACCGAA
CTCAATAAGGCACGCTTGGAAGCTCAGGAAATCGTTGATTTGGCTTTGTCAGAGAGTGAGAGCATTCTCAAAAATCTCCA
TGACAAGTCCAGTCTCAAACCGCATGAGATTATTGAAGCCAAAGCGCAGCTTAAAAAGTTGGCACCAGAAACGGTTGATT
TATCAAAGAATAAGGTGCTCAAGCAGGCCAAGAAAAATCGGGCGCCCAAGGTGGGAGATGATATCCTAGTCACCAGCTAT
GGTCAGCGGGGAACCTTGGTCAAGCAGCTCAAGGACGGCCGTTGGGAAGCCCAGGTCGGTCTTATCAAGATGACTCTAGA
AGAGCAGGAATTCAACTTACTCAAAGCTGAAAAGGAGCAGCAACCTAAGCGCAAGCAGGTCAATGTGGTCAAGCGGGCCA
ATACTGCTGGACCGAAAGCCAGACTGGATCTGCGGGGTAAACGCTACGAAGAGGCCATGGAAGAGCTTGATGCCTTTATC
GATCAGGCCCTCCTCAATAACATGGCTCAGGTGGACATTATCCACGGTATTGGGACCGGGGTCATCCGTGAAGGGGTGAC
AAAATACCTCCGCCGCAACAAGCACGTTAAGTCTTTCGGCTATGCTCCGCAAAATGCCGGCGGCAGCGGTGCGACGATTG
TAATCTTTAAGTAA

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(324-505)

Smr domain (Smr)

(702-777)

MutS2 and Smr-associated SH3 domain (MSSS)

(631-668)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3CKV4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

38.91

100

0.395

Multiple sequence alignment