Detailed information NTG0262352

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: C0J00_RS06560
• Genome accession: NZ_CP025536
• Coordinates: 1281365..1282246 (-)
• Length: 293 a.a.
• NCBI ID: WP_104968116.1
• Uniprot ID: A0A2L0D4N6
• Organism: Streptococcus pluranimalium strain TH11417
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1276365..1287246

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C0J00_RS06545 (C0J00_06550)	pheT	1276769..1279174 (-)	2406	WP_104968113.1	phenylalanine--tRNA ligase subunit beta	-
C0J00_RS06550 (C0J00_06555)	-	1279366..1279893 (-)	528	WP_104968114.1	GNAT family N-acetyltransferase	-
C0J00_RS06555 (C0J00_06560)	pheS	1279905..1280948 (-)	1044	WP_104968115.1	phenylalanine--tRNA ligase subunit alpha	-
C0J00_RS06560 (C0J00_06565)	endA	1281365..1282246 (-)	882	WP_104968116.1	DNA/RNA non-specific endonuclease	Machinery gene
C0J00_RS06565 (C0J00_06570)	-	1282280..1282468 (-)	189	WP_104968117.1	DNA-directed RNA polymerase subunit beta	-
C0J00_RS06570 (C0J00_06575)	murA	1282470..1283738 (-)	1269	WP_104968118.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
C0J00_RS06575 (C0J00_06580)	-	1283780..1284016 (-)	237	WP_104968119.1	DUF1146 family protein	-
C0J00_RS06580 (C0J00_06585)	-	1284315..1284731 (-)	417	WP_104968120.1	F0F1 ATP synthase subunit epsilon	-
C0J00_RS06585 (C0J00_06590)	atpD	1284744..1286150 (-)	1407	WP_104968121.1	F0F1 ATP synthase subunit beta	-
C0J00_RS06590 (C0J00_06595)	-	1286246..1287121 (-)	876	WP_104968122.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31910.41 Da
• Isoelectric Point: 8.3402

>NTDB_id=262352 C0J00_RS06560 WP_104968116.1 1281365..1282246(-) (endA) [Streptococcus pluranimalium strain TH11417]
MVKPYDVKKSSKSKFSVLVVIITLILGLVAGTDQLSDDNPLKQLAQVVTNGSNQEKVNSNGSSANESTPNQDLAQSVLTS
SVRKSLGDDIKWNGAGAFVINNNITNLDASVSSMPYVDNKIKRVQGKLVPSVANAMLSKQSRQYRNRELTGNGSTSWKPA
GWHQVHDLPGEYDHAIDRGHLIGYAIAGNIDGFDPSASNPQNIAVQTAWSNQARDHDSTGQNYYETQIRRALDNNKRVRY
RVTLVYEGDNIIASGSHLEAKSSDGSLEFNVFVPNVQPGITLNYANGQVTVNH

Nucleotide

• Length: 882 bp

>NTDB_id=262352 C0J00_RS06560 WP_104968116.1 1281365..1282246(-) (endA) [Streptococcus pluranimalium strain TH11417]
ATGGTTAAACCTTATGATGTAAAAAAATCATCTAAATCGAAGTTTTCTGTTCTAGTAGTCATTATAACCTTAATCTTAGG
TCTTGTTGCAGGGACAGATCAGCTGTCAGATGATAACCCTCTGAAACAGCTAGCTCAAGTTGTGACGAATGGTTCAAATC
AGGAAAAAGTAAATTCTAACGGCTCAAGTGCAAATGAATCGACACCAAACCAAGACTTAGCACAATCTGTTTTGACGTCA
TCTGTTAGAAAATCTTTAGGAGATGATATCAAATGGAATGGTGCAGGTGCCTTTGTGATTAATAACAATATAACAAATCT
TGATGCCAGTGTGTCCAGCATGCCTTATGTGGATAATAAAATAAAGCGGGTCCAAGGAAAGCTTGTCCCGTCAGTAGCAA
ATGCTATGCTGTCTAAACAAAGTCGACAATATCGTAACCGTGAATTAACGGGGAATGGGTCAACGTCATGGAAGCCGGCA
GGCTGGCATCAGGTTCATGATTTACCAGGTGAATACGATCATGCTATTGATCGAGGTCACTTAATTGGTTACGCCATTGC
GGGTAATATTGATGGTTTTGACCCTTCTGCAAGTAACCCTCAAAATATCGCTGTTCAGACAGCTTGGTCTAACCAAGCTA
GAGATCATGATTCAACGGGTCAAAACTATTATGAGACACAAATTCGTCGTGCTTTAGATAATAATAAACGTGTTCGTTAT
CGTGTGACTCTTGTTTATGAAGGCGATAATATCATTGCTTCTGGCTCGCATCTTGAAGCCAAATCAAGTGATGGTAGTTT
GGAATTTAATGTTTTTGTACCAAATGTTCAACCTGGTATTACGCTTAACTATGCTAATGGGCAGGTGACAGTTAATCACT
AA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (97-251)

3D structure

• AlphaFold DB: A0A2L0D4N6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	59.917	82.594	0.495
endA	Streptococcus pneumoniae D39	59.917	82.594	0.495
endA	Streptococcus pneumoniae R6	59.917	82.594	0.495
endA	Streptococcus pneumoniae TIGR4	59.917	82.594	0.495