Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   DK876_RS01210 Genome accession   NZ_CP030022
Coordinates   223960..226293 (+) Length   777 a.a.
NCBI ID   WP_012775425.1    Uniprot ID   A0A0H3MT16
Organism   Streptococcus suis strain ISU2714     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 218960..231293
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK876_RS01190 (DK876_01255) treP 219954..221948 (-) 1995 WP_011921815.1 PTS system trehalose-specific EIIBC component -
  DK876_RS01195 (DK876_01260) treR 222182..222895 (+) 714 WP_012774930.1 trehalose operon repressor Regulator
  DK876_RS01200 (DK876_01265) - 222953..223264 (+) 312 WP_002935948.1 hypothetical protein -
  DK876_RS01205 (DK876_01270) - 223261..223809 (+) 549 WP_002935945.1 CvpA family protein -
  DK876_RS01210 (DK876_01275) mutS/mutS2 223960..226293 (+) 2334 WP_012775425.1 endonuclease MutS2 Machinery gene
  DK876_RS01215 (DK876_01280) - 226317..226970 (+) 654 WP_011921818.1 GNAT family N-acetyltransferase -
  DK876_RS01220 (DK876_01285) trxA 227177..227491 (+) 315 WP_012775426.1 thioredoxin -
  DK876_RS10205 - 227719..227769 (-) 51 WP_353735889.1 hypothetical protein -
  DK876_RS01225 (DK876_01290) - 227759..229288 (+) 1530 WP_012774931.1 AMP-binding protein -
  DK876_RS01230 (DK876_01295) msrB 229328..230266 (+) 939 WP_011921822.1 peptide-methionine (R)-S-oxide reductase MsrB -
  DK876_RS01235 (DK876_01300) - 230384..231262 (+) 879 WP_014635840.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 777 a.a.        Molecular weight: 87550.34 Da        Isoelectric Point: 6.8323

>NTDB_id=258241 DK876_RS01210 WP_012775425.1 223960..226293(+) (mutS/mutS2) [Streptococcus suis strain ISU2714]
MNNKIIETLEFHKVRQKIEPYLLTEQGFEELRQLEPMVEVHRIQQAFDELTDIAQIFVENPYFSLAATSDIGPAMRRLEL
DTDLNIAELLAVKKVLEVSKSLLDFYGNLENVSLSQLDKLFEKIELFPHLQGSLQSINDAGFVEDFASEKLARIRRKIRE
AEDQVRQVMQDILKTKGDMLSDSILASRNGRNVLPVKNTYRNKIAGVVHDISASGSTVYIEPRAVVTLNEEISHLRAEER
HELNRILQELSDMLRPHGGVIRNNAWLIGHIDFVRAKHLFARDHQAVVPKLSEKQDIALLNVRHPLIAKPVPNDLYFGSQ
LTAIVITGPNTGGKTIMLKTLGLTHLMAQSGLPILADKGSRVAIFKEIFADIGDEQSIEQSLSTFSSHMTHTVEILRAAD
QDSLILFDELGAGTDPQEGASLAMAILDDLRLRGIKTMATTHYPELKAYGIETSGIENASMEFDSNSLRPTYKFMQGVPG
RSNAFEIARRLGLSDIIIQSAQSWTDTDSDVNRIIEKLESQTVESRQRLDKIRDVEQENYKMNRALRKLYDELNRERENE
LNKARLEAKEIVDMALAESEDILKNLHAAASLKPHQIIEAKAELKKLAPEVVDLSKNKVLKKAKIKREAKVGDDIIVTAY
GQRGTLTNQLKDGRWEAQVGLIKMTLAKDEFELVKAEKAEQPKKRQVHTVKRANVRGPKARLDLRGKRYEEAMMELDEFI
DQALLNNLAQVDIVHGIGTGVIREGVTKYLRRNKQIKEFGYAPQNAGGSGCTIVTFK

Nucleotide


Download         Length: 2334 bp        

>NTDB_id=258241 DK876_RS01210 WP_012775425.1 223960..226293(+) (mutS/mutS2) [Streptococcus suis strain ISU2714]
ATGAATAATAAAATTATTGAAACCCTTGAATTTCACAAGGTAAGACAAAAAATTGAGCCCTATCTCTTGACGGAACAGGG
CTTTGAAGAATTACGACAGTTGGAGCCCATGGTGGAAGTCCATCGTATCCAACAGGCCTTCGACGAGTTGACAGACATAG
CGCAGATTTTTGTGGAAAATCCCTATTTCAGTCTGGCTGCTACTAGTGACATCGGTCCAGCCATGCGTCGTTTGGAATTG
GATACAGACCTCAATATCGCTGAATTATTAGCTGTTAAAAAGGTCTTGGAAGTTTCTAAATCTCTCTTGGATTTTTATGG
AAATCTGGAAAATGTCAGTCTTAGCCAGTTGGATAAACTCTTTGAGAAGATTGAGCTTTTTCCACATTTACAGGGCTCCC
TCCAGTCCATCAATGATGCTGGTTTTGTAGAGGATTTTGCCTCAGAAAAGCTGGCTCGTATTCGAAGAAAAATCCGTGAA
GCTGAAGATCAAGTTCGTCAGGTCATGCAGGATATTTTGAAGACCAAGGGCGACATGCTGTCCGATAGCATTTTGGCAAG
CCGTAATGGACGCAATGTCCTTCCTGTTAAAAATACCTATCGCAATAAGATTGCAGGGGTTGTCCATGACATTTCAGCTT
CGGGTTCGACCGTTTATATTGAGCCGCGGGCAGTGGTGACCTTGAACGAAGAAATCAGTCACCTACGTGCAGAAGAACGC
CATGAGCTCAACCGTATCTTGCAGGAATTGTCGGATATGCTCCGTCCGCATGGTGGCGTGATTCGTAACAATGCCTGGCT
TATCGGACATATTGATTTCGTCCGTGCTAAGCATCTCTTTGCGCGTGATCATCAAGCAGTTGTACCCAAACTATCTGAGA
AGCAGGATATTGCCCTTCTCAACGTTCGGCATCCGCTCATTGCTAAGCCTGTACCAAATGACCTTTATTTCGGTAGTCAG
TTGACGGCTATCGTGATAACAGGTCCCAACACAGGTGGTAAGACCATCATGCTTAAGACCTTGGGATTGACCCATCTGAT
GGCCCAGTCTGGTTTGCCTATCTTGGCTGATAAGGGCAGTCGGGTAGCTATCTTCAAAGAAATTTTTGCGGATATTGGGG
ATGAACAGTCGATTGAGCAGAGTTTATCAACCTTCTCCAGTCACATGACCCACACGGTGGAAATTTTAAGAGCAGCTGAT
CAAGATTCTCTCATTCTCTTTGACGAGTTGGGAGCTGGGACAGATCCGCAGGAGGGTGCGTCTTTGGCTATGGCTATTTT
GGATGACCTTCGTCTGCGGGGGATCAAGACCATGGCGACCACCCACTACCCTGAGCTTAAGGCCTACGGGATAGAAACCT
CTGGTATTGAAAATGCCAGCATGGAGTTTGATAGCAATAGCCTGCGTCCGACCTATAAGTTTATGCAGGGTGTTCCTGGT
CGCTCCAATGCCTTTGAAATTGCCCGCCGTCTTGGTCTATCTGATATTATTATCCAGTCAGCCCAATCTTGGACGGATAC
AGATAGCGATGTGAACCGCATTATCGAGAAATTGGAAAGTCAGACGGTTGAAAGTCGTCAACGTCTGGATAAGATTCGTG
ATGTGGAGCAAGAAAATTACAAGATGAACCGAGCCCTCCGCAAGCTCTATGACGAGCTCAATCGTGAGCGGGAAAATGAG
CTCAACAAGGCACGCTTGGAAGCCAAGGAAATTGTAGATATGGCATTGGCAGAAAGCGAGGATATTCTCAAAAATCTCCA
TGCTGCAGCTAGTCTTAAGCCCCATCAGATTATCGAAGCCAAGGCAGAGCTGAAAAAGTTGGCGCCTGAAGTGGTGGATC
TGTCTAAAAACAAGGTTCTGAAGAAAGCTAAAATTAAGAGGGAAGCCAAGGTGGGCGATGACATTATCGTTACAGCTTAT
GGACAACGCGGGACCTTGACCAATCAGCTCAAGGACGGGCGTTGGGAAGCTCAGGTTGGCTTGATTAAGATGACCTTGGC
TAAAGATGAGTTTGAGTTAGTCAAGGCGGAAAAGGCAGAGCAGCCTAAGAAACGCCAGGTTCACACAGTCAAACGTGCCA
ATGTACGAGGACCAAAAGCCCGCTTAGATCTCCGTGGCAAACGTTACGAAGAGGCTATGATGGAGCTGGATGAATTTATC
GACCAGGCCCTTCTCAATAACCTAGCCCAAGTCGATATTGTCCACGGTATTGGTACTGGAGTCATCCGAGAAGGGGTGAC
CAAGTACCTACGCCGCAACAAGCAGATCAAGGAGTTCGGCTATGCCCCACAAAATGCAGGTGGATCAGGCTGTACTATTG
TGACGTTTAAATAG

Domains

Predicted by InterProScan.

MutS2 and Smr-associated SH3 domain (MSSS)

(631-670)

MutS domain V (MutS_V)

(324-504)

Smr domain (Smr)

(702-777)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MT16

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

39.52

100

0.403

Multiple sequence alignment