Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   CUC43_RS30085 Genome accession   NZ_CP024771
Coordinates   5667775..5668554 (-) Length   259 a.a.
NCBI ID   WP_000421290.1    Uniprot ID   A0A9W5VKA1
Organism   Bacillus thuringiensis LM1212     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 5631898..5685811 5667775..5668554 within 0


Gene organization within MGE regions


Location: 5631898..5685811
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CUC43_RS29920 (CUC43_30880) - 5632786..5632989 (-) 204 WP_029439580.1 YlzJ-like family protein -
  CUC43_RS29925 (CUC43_30885) tepA 5632986..5633735 (-) 750 WP_029439581.1 translocation-enhancing protein TepA -
  CUC43_RS29930 (CUC43_30890) - 5633838..5635508 (-) 1671 WP_000823084.1 ribonuclease J -
  CUC43_RS29940 (CUC43_30900) dapA 5636266..5637144 (-) 879 WP_029439583.1 4-hydroxy-tetrahydrodipicolinate synthase -
  CUC43_RS29945 (CUC43_30905) dapG 5637156..5638388 (-) 1233 WP_001978141.1 aspartate kinase -
  CUC43_RS29950 (CUC43_30910) asd 5638412..5639458 (-) 1047 WP_000414855.1 aspartate-semialdehyde dehydrogenase -
  CUC43_RS29955 (CUC43_30915) dpaB 5639609..5640208 (-) 600 WP_001049480.1 dipicolinate synthase subunit B -
  CUC43_RS29960 (CUC43_30920) dpaA 5640205..5641107 (-) 903 WP_000954726.1 dipicolinic acid synthetase subunit A -
  CUC43_RS29965 (CUC43_30925) - 5641347..5641598 (-) 252 WP_029439584.1 YlmC/YmxH family sporulation protein -
  CUC43_RS29970 (CUC43_30930) - 5641729..5642970 (-) 1242 WP_000592994.1 pitrilysin family protein -
  CUC43_RS29975 (CUC43_30935) - 5643057..5643956 (-) 900 WP_000647529.1 polysaccharide deacetylase family protein -
  CUC43_RS29980 (CUC43_30940) pnp 5644107..5646245 (-) 2139 WP_029439585.1 polyribonucleotide nucleotidyltransferase -
  CUC43_RS29985 (CUC43_30945) rpsO 5646406..5646675 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  CUC43_RS29990 (CUC43_30950) ribF 5646776..5647747 (-) 972 WP_000766719.1 bifunctional riboflavin kinase/FAD synthetase -
  CUC43_RS29995 (CUC43_30955) truB 5647791..5648714 (-) 924 WP_000399340.1 tRNA pseudouridine(55) synthase TruB -
  CUC43_RS30000 (CUC43_30960) rbfA 5648801..5649157 (-) 357 WP_000776442.1 30S ribosome-binding factor RbfA -
  CUC43_RS30005 (CUC43_30965) - 5649173..5649454 (-) 282 WP_000582364.1 DUF503 family protein -
  CUC43_RS30010 (CUC43_30970) infB 5649451..5651511 (-) 2061 WP_000036341.1 translation initiation factor IF-2 -
  CUC43_RS30015 (CUC43_30975) - 5651516..5651827 (-) 312 WP_001286518.1 YlxQ family RNA-binding protein -
  CUC43_RS30020 (CUC43_30980) - 5651828..5652100 (-) 273 WP_000071128.1 YlxR family protein -
  CUC43_RS30025 (CUC43_30985) nusA 5652112..5653218 (-) 1107 WP_000102609.1 transcription termination factor NusA -
  CUC43_RS30030 (CUC43_30990) rimP 5653236..5653706 (-) 471 WP_000359097.1 ribosome maturation factor RimP -
  CUC43_RS30035 (CUC43_30995) - 5654039..5658340 (-) 4302 WP_029439586.1 PolC-type DNA polymerase III -
  CUC43_RS30040 (CUC43_31005) - 5658465..5660165 (-) 1701 WP_029439587.1 proline--tRNA ligase -
  CUC43_RS30045 (CUC43_31010) rseP 5660275..5661531 (-) 1257 WP_001090234.1 RIP metalloprotease RseP -
  CUC43_RS30050 (CUC43_31015) dxr 5661548..5662690 (-) 1143 WP_029439588.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  CUC43_RS30055 (CUC43_31020) cdsA 5662714..5663505 (-) 792 WP_000813584.1 phosphatidate cytidylyltransferase -
  CUC43_RS30060 (CUC43_31025) uppS 5663523..5664299 (-) 777 WP_029439589.1 isoprenyl transferase -
  CUC43_RS30065 (CUC43_31030) frr 5664385..5664942 (-) 558 WP_000531501.1 ribosome recycling factor -
  CUC43_RS30070 (CUC43_31035) pyrH 5664945..5665667 (-) 723 WP_000042663.1 UMP kinase -
  CUC43_RS30075 (CUC43_31040) tsf 5665734..5666621 (-) 888 WP_029439590.1 translation elongation factor Ts -
  CUC43_RS30080 (CUC43_31045) rpsB 5666725..5667426 (-) 702 WP_000111485.1 30S ribosomal protein S2 -
  CUC43_RS30085 (CUC43_31050) codY 5667775..5668554 (-) 780 WP_000421290.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  CUC43_RS30090 (CUC43_31055) hslU 5668632..5670023 (-) 1392 WP_000550082.1 ATP-dependent protease ATPase subunit HslU -
  CUC43_RS30095 (CUC43_31060) hslV 5670046..5670588 (-) 543 WP_000526274.1 ATP-dependent protease proteolytic subunit HslV -
  CUC43_RS30100 (CUC43_31065) xerC 5670631..5671530 (-) 900 WP_029439591.1 tyrosine recombinase XerC -
  CUC43_RS30105 (CUC43_31070) trmFO 5671596..5672900 (-) 1305 WP_029439592.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  CUC43_RS30110 (CUC43_31075) topA 5672951..5675029 (-) 2079 WP_029439593.1 type I DNA topoisomerase -
  CUC43_RS30115 (CUC43_31080) - 5675174..5675560 (-) 387 Protein_5825 DNA-processing protein DprA -
  CUC43_RS30125 (CUC43_31090) - 5676406..5676894 (-) 489 Protein_5827 DNA-processing protein DprA -
  CUC43_RS30130 (CUC43_31095) sucD 5676982..5677884 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  CUC43_RS30135 (CUC43_31100) sucC 5677904..5679064 (-) 1161 WP_001020785.1 ADP-forming succinate--CoA ligase subunit beta -
  CUC43_RS30140 (CUC43_31105) rnhB 5679258..5680031 (-) 774 WP_029439595.1 ribonuclease HII -
  CUC43_RS30145 (CUC43_31110) ylqF 5680083..5680973 (-) 891 WP_000236700.1 ribosome biogenesis GTPase YlqF -
  CUC43_RS30150 (CUC43_31115) lepB 5680994..5681545 (-) 552 WP_029439596.1 signal peptidase I -
  CUC43_RS30155 (CUC43_31120) rplS 5681647..5681991 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  CUC43_RS30160 (CUC43_31125) trmD 5682138..5682872 (-) 735 WP_029439597.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  CUC43_RS30165 (CUC43_31130) rimM 5682872..5683387 (-) 516 WP_000170268.1 ribosome maturation factor RimM -
  CUC43_RS30170 (CUC43_31135) - 5683509..5683736 (-) 228 WP_000737398.1 KH domain-containing protein -
  CUC43_RS30175 (CUC43_31140) rpsP 5683751..5684023 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  CUC43_RS30180 (CUC43_31145) ffh 5684124..5685473 (-) 1350 WP_000863460.1 signal recognition particle protein -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28793.05 Da        Isoelectric Point: 4.7165

>NTDB_id=255388 CUC43_RS30085 WP_000421290.1 5667775..5668554(-) (codY) [Bacillus thuringiensis LM1212]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENRELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLQELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=255388 CUC43_RS30085 WP_000421290.1 5667775..5668554(-) (codY) [Bacillus thuringiensis LM1212]
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAACCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAATGTGTTCGTAGTAAGCCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATTGAGAATGAGCGTATGAAACAAATGCTTGCAGAGCGTCAATTCCCAGAAGAGTATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAACAGTGCTTACACAGCATTCCCAGTAGAAAATAGAGAATTATTCGG
TCAAGGTTTAACTACAATCGTACCAATCGTTGGTGGCGGTGAGCGTCTAGGCACATTAGTGTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATCCTTGCTGAATACAGTTCAACTGTAGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATCGAAGAGGAAGCACGTAGTAAAGCTGTTGTTCAAATGGCGATTAGCTCATTATCTTACAGTGAGTTAGAAGCAAT
CGAGCATATCTTCGAAGAATTAAATGGAACAGAAGGATTACTTGTTGCAAGTAAAATTGCTGATCGCGTAGGAATTACTC
GTTCTGTAATCGTAAATGCATTACGTAAATTAGAAAGTGCTGGTGTTATTGAGTCTCGCTCTTTAGGTATGAAAGGAACA
TACATTAAAGTGCTAAACGACAAGTTTCTACAGGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.467

100

0.815
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459

Multiple sequence alignment