Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   DK181_RS08975 Genome accession   NZ_CP029490
Coordinates   1838702..1840534 (-) Length   610 a.a.
NCBI ID   WP_002960234.1    Uniprot ID   A0ABM6W7A4
Organism   Streptococcus sobrinus strain SL1     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1833702..1845534
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK181_RS08950 (DK182_08950) - 1834249..1834506 (-) 258 WP_002960229.1 hypothetical protein -
  DK181_RS08955 (DK182_08955) - 1834648..1836117 (-) 1470 WP_002960230.1 LPXTG cell wall anchor domain-containing protein -
  DK181_RS08960 (DK182_08960) - 1836152..1837174 (-) 1023 WP_002960231.1 LPXTG cell wall anchor domain-containing protein -
  DK181_RS08965 (DK182_08965) - 1837194..1838261 (-) 1068 WP_002960232.1 hypothetical protein -
  DK181_RS08970 (DK182_08970) - 1838275..1838601 (-) 327 WP_002960233.1 hypothetical protein -
  DK181_RS08975 (DK182_08975) clpE 1838702..1840534 (-) 1833 WP_002960234.1 AAA family ATPase Regulator
  DK181_RS08980 (DK182_08980) - 1840524..1842269 (-) 1746 WP_002960235.1 type IA DNA topoisomerase -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 67868.35 Da        Isoelectric Point: 4.7909

>NTDB_id=253769 DK181_RS08975 WP_002960234.1 1838702..1840534(-) (clpE) [Streptococcus sobrinus strain SL1]
MAGETEQKPSVLEEFANNLSSKVLSKPDDYEVYGRDEEVEDVILALLRKGKNSPVLIGEPGVGKTAVVEGLALRIARGQV
PARLQGLTVYNLELSSLTGEGDFIAKFKQIIDELVDRRGEVLMFMDEIHTIVGAGGQEGQALDAGNVIKPVLARGEIQLI
GATTLDEYHQYIETDKALERRMPPIMIDEPSEEEAITILNLAKAPYEEFHQVTYSEEAIRQAVSLSIRYITDKYLPDKAF
DLIDEAGSLAASRGQIEITEAEVAEILRRKTGIPVTTILQGTDDRLEKLSDALHQRVKGQDGVIDAMIRAVSIAQEGLQD
ESKPFGTFLLLGPTGVGKTEFAKATAQGLFGSEESLIRFDMSEYMEKGDDKKLIGDAKTGTKGDLTEKVKRRPYSVLLFD
EIEKADASVLDLFLQILDDGRLTDATGRLVSFKNTLVLMTTNLGARKVNDQFDIKGDIDKLDNEQLKKLEKNMNRVLKND
LRPEFINRFDYKLIFNVLTEKLILKIVDKDMDLVAQRLAKHGMSVSYDQAVANYLSRNGTDEKNGARPLARLISDEVVAP
IADLKRRLRREHGSSAGYHIIISAVGELKDESHRKERQHLEFEAILQEVA

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=253769 DK181_RS08975 WP_002960234.1 1838702..1840534(-) (clpE) [Streptococcus sobrinus strain SL1]
ATGGCAGGTGAAACCGAACAGAAACCAAGTGTTTTAGAGGAATTTGCGAATAATTTATCGTCCAAGGTTTTGTCTAAACC
TGACGATTATGAAGTTTATGGCCGTGATGAAGAAGTGGAAGATGTTATCCTTGCCCTTCTGAGAAAGGGAAAGAATAGTC
CTGTTTTAATCGGTGAGCCAGGTGTCGGTAAGACTGCCGTTGTTGAAGGGCTAGCTCTAAGAATTGCTAGGGGACAGGTT
CCTGCCCGATTACAAGGACTAACCGTCTATAACCTAGAACTCTCTAGCTTGACTGGTGAGGGTGATTTTATTGCTAAATT
TAAGCAGATTATTGATGAACTAGTTGACCGACGAGGCGAAGTTTTAATGTTTATGGATGAAATTCATACCATTGTTGGGG
CTGGCGGTCAGGAAGGCCAAGCCCTTGATGCAGGGAATGTTATCAAACCAGTCCTCGCTCGTGGGGAAATTCAATTAATT
GGTGCGACTACTTTGGATGAATATCACCAATACATTGAAACAGACAAAGCCCTAGAGCGGCGGATGCCACCAATCATGAT
TGATGAACCGTCAGAAGAAGAAGCTATAACAATTCTCAACTTGGCCAAGGCTCCTTATGAAGAGTTTCACCAAGTGACCT
ATTCTGAGGAAGCTATTCGTCAAGCGGTTAGTCTATCTATACGCTATATCACCGATAAATACCTACCTGACAAGGCCTTT
GATTTAATTGACGAAGCAGGAAGCCTAGCTGCTAGTAGAGGACAAATTGAAATTACTGAAGCTGAAGTTGCTGAAATTCT
CAGACGAAAAACAGGTATTCCAGTTACCACTATCCTTCAAGGTACTGATGACCGACTGGAAAAGTTATCTGATGCCCTTC
ATCAAAGAGTTAAAGGTCAGGATGGTGTGATTGATGCCATGATTAGGGCCGTCTCTATCGCCCAGGAAGGCCTGCAGGAT
GAATCTAAGCCCTTTGGAACATTCCTTTTGCTTGGTCCTACTGGGGTTGGGAAAACGGAGTTTGCTAAGGCAACAGCTCA
AGGTCTCTTTGGTTCCGAGGAGTCTTTAATCCGCTTTGACATGTCTGAATATATGGAAAAAGGAGACGATAAGAAGCTGA
TTGGGGATGCTAAAACTGGAACGAAAGGGGACTTGACCGAGAAAGTCAAACGGAGACCTTATAGTGTTTTGCTCTTTGAT
GAAATTGAAAAGGCTGATGCCAGTGTTCTAGACTTGTTTTTACAGATTTTGGATGATGGTCGCTTGACAGATGCGACTGG
ACGGCTGGTAAGTTTCAAGAATACCCTAGTTTTAATGACGACCAACCTGGGTGCTCGGAAGGTAAATGATCAGTTTGACA
TTAAAGGGGATATTGACAAACTGGACAATGAGCAATTGAAAAAGCTTGAAAAGAATATGAACAGGGTTCTAAAAAATGAC
TTACGTCCTGAGTTTATTAACCGCTTTGACTATAAACTGATTTTCAATGTTTTGACAGAGAAACTTATTTTGAAAATTGT
CGATAAGGATATGGATTTAGTTGCCCAACGCCTAGCTAAACATGGTATGAGTGTTAGCTATGATCAGGCAGTCGCCAATT
ATTTATCTCGTAATGGAACCGATGAGAAAAATGGTGCTCGACCATTGGCCCGTCTTATTTCAGACGAAGTTGTCGCTCCA
ATCGCTGATTTAAAGCGACGACTCAGAAGAGAACACGGCTCATCTGCGGGCTATCATATTATTATTTCGGCGGTTGGGGA
GTTAAAGGATGAGTCCCACAGAAAGGAACGGCAGCACTTGGAATTTGAAGCCATCTTGCAAGAAGTTGCGTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(498-564)

AAA domain (Cdc48 subfamily) (AAA_2)

(324-490)

ATPase family associated with various cellular activities (AAA) (AAA)

(55-165)

AAA lid domain (AAA_lid_9)

(191-260)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

43.75

100

0.448
  clpC Lactococcus lactis subsp. cremoris KW2

43.8

100

0.446
  clpE Streptococcus pneumoniae Rx1

40.553

100

0.433
  clpE Streptococcus pneumoniae D39

40.553

100

0.433
  clpE Streptococcus pneumoniae R6

40.553

100

0.433
  clpE Streptococcus pneumoniae TIGR4

40.553

100

0.433
  clpC Streptococcus pneumoniae Rx1

39.675

100

0.4
  clpC Streptococcus pneumoniae D39

39.675

100

0.4
  clpC Streptococcus pneumoniae TIGR4

39.512

100

0.398
  clpC Streptococcus thermophilus LMG 18311

41.796

94.918

0.397
  clpC Streptococcus mutans UA159

39.474

99.672

0.393
  clpC Streptococcus thermophilus LMD-9

41.451

94.918

0.393