Detailed information NTG0251978

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: DD562_RS14025
• Genome accession: NZ_CP029172
• Coordinates: 2710181..2712289 (+)
• Length: 702 a.a.
• NCBI ID: WP_031867461.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain PTDrAP2
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2705181..2717289

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DD562_RS14000 (DD562_14000)	-	2705202..2705420 (+)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-
DD562_RS14005 (DD562_14005)	-	2705808..2706239 (+)	432	WP_000875614.1	CHAP domain-containing protein	-
DD562_RS14010 (DD562_14010)	-	2706379..2707659 (-)	1281	WP_001191004.1	hydroxymethylglutaryl-CoA reductase, degradative	-
DD562_RS14015 (DD562_14015)	-	2707914..2709080 (+)	1167	WP_000151980.1	hydroxymethylglutaryl-CoA synthase	-
DD562_RS14020 (DD562_14020)	-	2709251..2709772 (-)	522	WP_000384652.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
DD562_RS14025 (DD562_14025)	clpE	2710181..2712289 (+)	2109	WP_031867461.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
DD562_RS14030 (DD562_14030)	-	2712356..2712526 (-)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
DD562_RS14035 (DD562_14035)	feoB	2712539..2714533 (-)	1995	WP_000432889.1	ferrous iron transport protein B	-
DD562_RS14040 (DD562_14040)	-	2714545..2714772 (-)	228	WP_000932073.1	FeoA family protein	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78039.41 Da
• Isoelectric Point: 4.5863

>NTDB_id=251978 DD562_RS14025 WP_031867461.1 2710181..2712289(+) (clpE) [Staphylococcus aureus strain PTDrAP2]
MNNGFFNSDFDSIFRRMMQDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGQQGGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDTEEKDIMHEMKKFFRPEFLNRFNDIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=251978 DD562_RS14025 WP_031867461.1 2710181..2712289(+) (clpE) [Staphylococcus aureus strain PTDrAP2]
ATGAATAACGGTTTTTTCAATAGCGACTTTGATTCAATTTTTCGAAGAATGATGCAAGATATGCAAGGTTCAAATCAAGT
CGGTAACAAAAAGTACTATATTAATGGTAAAGAAGTTTCACCTGAAGAACTAGCGCAACTCACACAACAAGGTGGCAATC
ACTCTGCTGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACAAAGACAACAAGGGCAACAAGGTGGCAACGGCAATTAT
TTAGAACAAATTGGCCGTAACCTTACGCAAGAAGCACGTGACGGTTTATTAGATCCAGTCATTGGTCGTGATAAAGAAAT
TCAAGAAACTGCTGAAGTTTTAAGTAGACGAACTAAAAACAATCCTATATTAGTTGGAGAAGCTGGTGTTGGTAAAACTG
CGATTGTTGAAGGTTTAGCACAGGCAATCGTTGAAGGGAATGTACCTGCAGCCATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAATATTCAAAAATTAATCGAAGGTGTTAA
ATCTTCACAAAATGCCGTACTATTCTTTGATGAAATCCATCAAATTATCGGTTCAGGTGCCACAGGAAGTGATTCAGGTA
GCAAAGGGTTATCTGATATTTTGAAACCTGCATTAAGTCGTGGTGAGATTTCTATTATTGGTGCAACAACACAAGATGAA
TATCGAAACAATATTCTTAAAGATGCTGCATTAACGCGCAGATTTAATGAAGTACTTGTTAATGAACCAAGTGCTAAAGA
TACTGTTGAAATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTCAAATTACCAGATGACGTATTAAAAG
CATGTGTTGACTTATCAATTCAATATATTCCACAACGATTATTACCAGATAAAGCAATCGATGTGTTAGATATTACAGCA
GCACATTTATCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACG
TAAAGCGGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGATAAATTAGAAA
ATAGTAATGGTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGATCA
AGCTGTAGAAATGGTTTCACGTGCAATTCGCCGTAATCGCGCTGGGTTTGATGACGGCAACCGTCCAATTGGTAGTTTCC
TATTTGTCGGCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCAATTGATCTATTTGGTAATAAAGATGCA
CTTATTCGACTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGACAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATACTCAGTCATTCTATTTGATGAAATCGAAA
AAGCAAATCCACAAATTTTAACATTATTACTACAAGTGATGGATGATGGTAATTTGACTGATGGTCAAGGTAACGTCATC
AACTTTAAAAACACAATCATTATTTGTACGTCAAACGCTGGTTTTGGTAACGGCAATGACACTGAAGAAAAAGACATTAT
GCATGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGACATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTACAAGATATCGTCAACTTATTATTAGACGATGTACAAGTTACATTAGATAAAAAAGGTATTACGATGGACGTT
TCTCAAGATGCGAAAGATTGGTTAATTGAAGAAGGTTATGATGAAGAATTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ATGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (448-605)

• AAA lid domain (AAA_lid_9) (264-363)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.678	91.595	0.446
clpE	Streptococcus pneumoniae Rx1	48.136	87.892	0.423
clpE	Streptococcus pneumoniae D39	48.136	87.892	0.423
clpE	Streptococcus pneumoniae R6	48.136	87.892	0.423
clpE	Streptococcus pneumoniae TIGR4	48.136	87.892	0.423
clpC	Lactococcus lactis subsp. cremoris KW2	46.361	90.028	0.417
clpC	Bacillus subtilis subsp. subtilis str. 168	44.564	93.02	0.415
clpC	Streptococcus thermophilus LMD-9	44.234	90.171	0.399
clpC	Streptococcus thermophilus LMG 18311	43.918	90.171	0.396
clpC	Streptococcus pneumoniae TIGR4	43.851	88.034	0.386
clpC	Streptococcus pneumoniae Rx1	43.851	88.034	0.386
clpC	Streptococcus pneumoniae D39	43.851	88.034	0.386
clpC	Streptococcus mutans UA159	43.577	87.607	0.382
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.294	92.45	0.382