Detailed information NTG0248513

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: CPQ89_RS10250
• Genome accession: NZ_CP023566
• Coordinates: 2074998..2075834 (-)
• Length: 278 a.a.
• NCBI ID: WP_112195640.1
• Uniprot ID: -
• Organism: Ligilactobacillus murinus strain CR141
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2069998..2080834

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CPQ89_RS10220 (CPQ89_10200)	-	2070139..2070744 (-)	606	WP_112195975.1	response regulator transcription factor	-
CPQ89_RS10225 (CPQ89_10205)	-	2070722..2071858 (-)	1137	WP_112195630.1	sensor histidine kinase	-
CPQ89_RS10230 (CPQ89_10210)	-	2071860..2072579 (-)	720	WP_112195632.1	ABC transporter permease	-
CPQ89_RS10235 (CPQ89_10215)	-	2072563..2073453 (-)	891	WP_112195634.1	ABC transporter ATP-binding protein	-
CPQ89_RS10240 (CPQ89_10220)	-	2073585..2074460 (-)	876	WP_112195636.1	CPBP family intramembrane glutamic endopeptidase	-
CPQ89_RS10245 (CPQ89_10225)	-	2074687..2074998 (-)	312	WP_112195638.1	MazG-like protein	-
CPQ89_RS10250 (CPQ89_10230)	endA	2074998..2075834 (-)	837	WP_112195640.1	DNA/RNA non-specific endonuclease	Machinery gene
CPQ89_RS10255 (CPQ89_10235)	asnA	2075894..2076901 (-)	1008	WP_112195642.1	aspartate--ammonia ligase	-
CPQ89_RS10260 (CPQ89_10240)	-	2077090..2077737 (+)	648	WP_112195644.1	nitroreductase	-
CPQ89_RS10265 (CPQ89_10245)	-	2077908..2078333 (-)	426	WP_112195646.1	N-acetyltransferase	-
CPQ89_RS10270 (CPQ89_10250)	-	2078401..2078787 (+)	387	WP_112195648.1	iron chaperone	-
CPQ89_RS10275 (CPQ89_10255)	-	2079556..2079822 (-)	267	WP_112195650.1	Na+-transporting malonate decarboxylase, carboxybiotin decarboxylase subunit, madB	-
CPQ89_RS11695 (CPQ89_10260)	-	2080150..2080530 (-)	381	WP_420324362.1	SA1002 family membrane protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30364.01 Da
• Isoelectric Point: 10.5129

>NTDB_id=248513 CPQ89_RS10250 WP_112195640.1 2074998..2075834(-) (endA) [Ligilactobacillus murinus strain CR141]
MKFKKILTGFAAALMLSGAIGAPVTAKATTHYGGWRTHQKNSSSGSGELKKSTPSQQLAQTVLTPDVVKQLGGEQNLKWN
NSGAFIVNNNKTDLKAKVSSAPYATNEVDSLKRPTVANALLNRTTRQYKNRHQTNNGSTKWKPQGFKQLTNLSGAYNHAY
DRGHLLGYALVGNIRGFDASESNPKNIATQTAWANEANAKYSTGQNYYESLVRKALDRNKTVRYRVTNVYSGNNLVPSGA
HLEAKASDGSLEYNVFIPNVQKGLKIDYATGHAIKENN

Nucleotide

• Length: 837 bp

>NTDB_id=248513 CPQ89_RS10250 WP_112195640.1 2074998..2075834(-) (endA) [Ligilactobacillus murinus strain CR141]
ATGAAGTTCAAAAAAATACTGACCGGATTTGCGGCAGCTTTGATGCTCAGTGGTGCGATCGGGGCACCGGTAACAGCTAA
AGCAACGACGCACTATGGTGGTTGGCGCACACATCAAAAAAATAGTTCGAGTGGCTCTGGTGAATTAAAAAAGAGCACTC
CATCACAACAATTAGCCCAAACGGTTTTGACGCCGGATGTTGTTAAACAATTGGGCGGTGAGCAAAATCTCAAATGGAAC
AACAGTGGGGCTTTTATCGTTAATAACAACAAGACAGATTTAAAAGCTAAGGTTTCTAGTGCTCCTTATGCAACAAATGA
AGTCGATAGCTTAAAACGTCCGACGGTAGCCAATGCCCTTTTGAATAGGACAACACGGCAATACAAGAATCGCCACCAAA
CTAATAATGGTTCGACTAAATGGAAACCACAGGGCTTTAAGCAACTCACTAACTTAAGTGGCGCCTACAACCATGCTTAT
GATCGCGGACACTTACTAGGGTATGCTTTAGTGGGAAATATTCGTGGTTTTGATGCTAGTGAGAGCAATCCCAAAAATAT
TGCGACTCAGACAGCTTGGGCTAATGAAGCTAATGCAAAATATTCAACAGGTCAAAACTATTACGAAAGTCTTGTTCGAA
AAGCCTTAGATCGTAATAAGACTGTCCGTTATCGTGTGACAAATGTCTATAGCGGTAATAATTTAGTACCATCAGGAGCT
CATTTAGAAGCTAAAGCAAGTGATGGTTCGTTAGAGTATAATGTTTTTATCCCTAATGTTCAAAAAGGATTAAAGATCGA
CTATGCTACTGGTCATGCGATAAAGGAGAACAACTGA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (82-250)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	65.471	80.216	0.525
endA	Streptococcus pneumoniae D39	65.471	80.216	0.525
endA	Streptococcus pneumoniae R6	65.471	80.216	0.525
endA	Streptococcus pneumoniae TIGR4	65.471	80.216	0.525