Detailed information NTG0248461

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: CPS94_RS01245
• Genome accession: NZ_CP023565
• Coordinates: 265196..266032 (+)
• Length: 278 a.a.
• NCBI ID: WP_112195640.1
• Uniprot ID: -
• Organism: Ligilactobacillus murinus strain CR147
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 260196..271032

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CPS94_RS01220 (CPS94_01215)	-	261208..261474 (+)	267	WP_112195650.1	Na+-transporting malonate decarboxylase, carboxybiotin decarboxylase subunit, madB	-
CPS94_RS01225 (CPS94_01220)	-	262243..262629 (-)	387	WP_112195648.1	iron chaperone	-
CPS94_RS01230 (CPS94_01225)	-	262697..263122 (+)	426	WP_112195646.1	N-acetyltransferase	-
CPS94_RS01235 (CPS94_01230)	-	263293..263940 (-)	648	WP_112195644.1	nitroreductase	-
CPS94_RS01240 (CPS94_01235)	asnA	264129..265136 (+)	1008	WP_112195642.1	aspartate--ammonia ligase	-
CPS94_RS01245 (CPS94_01240)	endA	265196..266032 (+)	837	WP_112195640.1	DNA/RNA non-specific endonuclease	Machinery gene
CPS94_RS01250 (CPS94_01245)	-	266032..266343 (+)	312	WP_112286321.1	MazG-like protein	-
CPS94_RS01255 (CPS94_01250)	-	266570..267445 (+)	876	WP_112286322.1	CPBP family intramembrane glutamic endopeptidase	-
CPS94_RS01260 (CPS94_01255)	-	267577..268467 (+)	891	WP_112286323.1	ABC transporter ATP-binding protein	-
CPS94_RS01265 (CPS94_01260)	-	268451..269170 (+)	720	WP_112286324.1	ABC transporter permease	-
CPS94_RS01270 (CPS94_01265)	-	269172..270308 (+)	1137	WP_112286325.1	sensor histidine kinase	-
CPS94_RS01275 (CPS94_01270)	-	270286..270891 (+)	606	WP_004049315.1	response regulator transcription factor	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30364.01 Da
• Isoelectric Point: 10.5129

>NTDB_id=248461 CPS94_RS01245 WP_112195640.1 265196..266032(+) (endA) [Ligilactobacillus murinus strain CR147]
MKFKKILTGFAAALMLSGAIGAPVTAKATTHYGGWRTHQKNSSSGSGELKKSTPSQQLAQTVLTPDVVKQLGGEQNLKWN
NSGAFIVNNNKTDLKAKVSSAPYATNEVDSLKRPTVANALLNRTTRQYKNRHQTNNGSTKWKPQGFKQLTNLSGAYNHAY
DRGHLLGYALVGNIRGFDASESNPKNIATQTAWANEANAKYSTGQNYYESLVRKALDRNKTVRYRVTNVYSGNNLVPSGA
HLEAKASDGSLEYNVFIPNVQKGLKIDYATGHAIKENN

Nucleotide

• Length: 837 bp

>NTDB_id=248461 CPS94_RS01245 WP_112195640.1 265196..266032(+) (endA) [Ligilactobacillus murinus strain CR147]
ATGAAGTTCAAAAAAATACTGACCGGATTTGCGGCAGCTTTGATGCTCAGTGGTGCGATCGGGGCACCGGTAACAGCTAA
AGCAACGACGCACTATGGTGGTTGGCGCACACATCAAAAAAATAGTTCGAGTGGCTCTGGTGAATTAAAAAAGAGCACTC
CATCACAACAATTAGCCCAAACGGTTTTGACGCCGGATGTTGTTAAACAATTGGGCGGTGAGCAAAATCTCAAATGGAAC
AACAGTGGGGCTTTTATCGTTAATAACAACAAGACAGATTTAAAAGCTAAGGTTTCTAGTGCTCCTTATGCAACAAATGA
AGTCGATAGCTTAAAACGTCCGACGGTAGCCAATGCCCTTTTGAATAGGACAACACGGCAATACAAGAATCGCCACCAAA
CTAATAATGGTTCGACTAAATGGAAACCACAGGGCTTTAAGCAACTCACTAACTTAAGTGGCGCCTACAACCATGCTTAT
GATCGCGGACACTTACTAGGGTATGCTTTAGTGGGAAATATTCGTGGTTTTGATGCTAGTGAGAGCAATCCCAAAAATAT
TGCGACTCAGACAGCTTGGGCTAATGAAGCTAATGCAAAATATTCAACAGGTCAAAACTATTACGAAAGTCTTGTTCGAA
AAGCCTTAGATCGTAATAAGACTGTCCGTTATCGTGTGACAAATGTCTATAGCGGTAATAATTTAGTACCATCAGGAGCT
CATTTAGAAGCTAAAGCAAGTGATGGTTCGTTAGAGTATAATGTTTTTATCCCTAATGTTCAAAAGGGATTAAAGATCGA
CTATGCTACTGGTCATGCGATAAAGGAGAATAACTGA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (82-250)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	65.471	80.216	0.525
endA	Streptococcus pneumoniae D39	65.471	80.216	0.525
endA	Streptococcus pneumoniae R6	65.471	80.216	0.525
endA	Streptococcus pneumoniae TIGR4	65.471	80.216	0.525