Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   CO687_RS09860 Genome accession   NZ_CP023511
Coordinates   2001892..2002731 (-) Length   279 a.a.
NCBI ID   WP_096755361.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS_371     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1996892..2007731
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO687_RS10670 (CO687_09835) - 1997621..1997728 (-) 108 Protein_1879 DNA-entry nuclease -
  CO687_RS09840 (CO687_09840) - 1998021..1999067 (+) 1047 WP_096755360.1 iron ABC transporter permease -
  CO687_RS09845 (CO687_09845) - 1999069..1999823 (+) 755 Protein_1881 ABC transporter ATP-binding protein -
  CO687_RS09850 (CO687_09850) - 1999968..2000996 (+) 1029 WP_061583530.1 ABC transporter substrate-binding protein -
  CO687_RS09855 (CO687_09855) - 2000977..2001678 (+) 702 WP_061583531.1 alpha/beta hydrolase-fold protein -
  CO687_RS09860 (CO687_09860) endA 2001892..2002731 (-) 840 WP_096755361.1 DNA/RNA non-specific endonuclease Machinery gene
  CO687_RS09865 (CO687_09865) - 2002776..2002964 (-) 189 WP_045502090.1 DNA-directed RNA polymerase subunit beta -
  CO687_RS09870 (CO687_09870) murA 2002957..2004237 (-) 1281 WP_096755362.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  CO687_RS09875 (CO687_09875) - 2004277..2004510 (-) 234 WP_096755363.1 DUF1146 family protein -
  CO687_RS09880 (CO687_09880) tpiA 2004640..2005398 (-) 759 WP_020992674.1 triose-phosphate isomerase -
  CO687_RS09885 (CO687_09885) tuf 2005672..2006868 (-) 1197 WP_020992675.1 elongation factor Tu -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30865.61 Da        Isoelectric Point: 10.1876

>NTDB_id=247995 CO687_RS09860 WP_096755361.1 2001892..2002731(-) (endA) [Streptococcus gordonii strain FDAARGOS_371]
MKKKQEEKLFQSIVGLILALVLIAGANYFSNHQNQDNIKSNPQVQRTGRRDISTPEQALSQSVLTDSVRKQLKGSIEWNQ
AGAFIINGNKTDLNADIASQPYAQNQTKSVQGQLVPIIGNALLSKQTRQYKNREETGNGTTSWVPAGWHQLRNLTGDFNH
AVDRGHLLAYSLVGGLKNFDASTSNPKNIAVQTAWANQANSPSSTGQNFYESLIRKALDKKKRVRYRVTLIYANPDDLIA
AGSHLEAKSNDGSLEFNVFVPNIQTGIRINYRTGEVTVE

Nucleotide


Download         Length: 840 bp        

>NTDB_id=247995 CO687_RS09860 WP_096755361.1 2001892..2002731(-) (endA) [Streptococcus gordonii strain FDAARGOS_371]
ATGAAGAAGAAACAAGAAGAGAAACTCTTTCAAAGCATAGTAGGACTGATTCTGGCACTTGTTCTGATAGCTGGTGCTAA
TTATTTCTCAAACCATCAGAATCAGGATAACATAAAGTCTAATCCACAGGTTCAAAGAACAGGAAGAAGGGATATCTCAA
CTCCCGAGCAAGCACTATCTCAGAGTGTATTGACTGATTCTGTTCGTAAGCAATTAAAAGGTAGCATAGAATGGAATCAG
GCAGGTGCTTTTATTATTAATGGCAACAAGACAGACCTGAATGCTGATATTGCCAGTCAGCCTTATGCACAAAATCAAAC
GAAGTCAGTCCAGGGACAGTTAGTACCAATAATTGGGAACGCACTGCTTTCTAAACAGACTAGACAATACAAAAATCGAG
AAGAAACAGGAAACGGGACGACAAGTTGGGTTCCTGCCGGCTGGCATCAGTTGAGAAATCTTACTGGAGATTTTAATCAT
GCTGTTGATCGAGGGCATTTATTAGCATATTCTTTAGTCGGAGGCTTAAAGAACTTCGATGCTTCTACAAGTAACCCAAA
GAATATCGCTGTTCAAACAGCTTGGGCAAATCAGGCAAACAGTCCTTCGTCTACTGGACAAAATTTTTATGAAAGCTTGA
TTCGGAAGGCTTTGGATAAAAAGAAGCGAGTCCGTTATCGAGTTACCTTGATTTATGCTAATCCTGATGACTTAATAGCA
GCGGGCTCTCATTTAGAAGCAAAGTCTAACGATGGAAGTCTTGAGTTTAATGTCTTCGTTCCAAATATTCAAACCGGGAT
TCGTATTAACTATAGAACTGGAGAAGTAACTGTAGAGTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(82-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

68.304

80.287

0.548
  endA Streptococcus pneumoniae D39

68.304

80.287

0.548
  endA Streptococcus pneumoniae R6

68.304

80.287

0.548
  endA Streptococcus pneumoniae TIGR4

68.304

80.287

0.548

Multiple sequence alignment