Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   M28_RS07735 Genome accession   NC_007296
Coordinates   1493673..1494455 (-) Length   260 a.a.
NCBI ID   WP_021340905.1    Uniprot ID   -
Organism   Streptococcus pyogenes MGAS6180     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1488673..1499455
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M28_RS07705 (M28_Spy1495) gatB 1488771..1490210 (-) 1440 WP_002983292.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  M28_RS07710 (M28_Spy1496) gatA 1490210..1491676 (-) 1467 WP_003053823.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  M28_RS07715 (M28_Spy1497) gatC 1491676..1491978 (-) 303 WP_011285093.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  M28_RS07720 (M28_Spy1498) - 1492210..1492434 (-) 225 WP_014635660.1 putative PEP-binding protein -
  M28_RS07730 (M28_Spy1500) - 1492972..1493526 (-) 555 WP_002988559.1 cysteine hydrolase family protein -
  M28_RS07735 (M28_Spy1501) codY 1493673..1494455 (-) 783 WP_021340905.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  M28_RS07740 (M28_Spy1502) - 1494673..1495887 (-) 1215 WP_010922605.1 pyridoxal phosphate-dependent aminotransferase -
  M28_RS07745 (M28_Spy1503) - 1496118..1496570 (+) 453 WP_002992571.1 universal stress protein -
  M28_RS07750 (M28_Spy1504) - 1496693..1498081 (-) 1389 WP_010922607.1 Cof-type HAD-IIB family hydrolase -
  M28_RS07755 (M28_Spy1505) - 1498153..1499118 (+) 966 WP_011285099.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28647.79 Da        Isoelectric Point: 4.5611

>NTDB_id=24726 M28_RS07735 WP_021340905.1 1493673..1494455(-) (codY) [Streptococcus pyogenes MGAS6180]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASIIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=24726 M28_RS07735 WP_021340905.1 1493673..1494455(-) (codY) [Streptococcus pyogenes MGAS6180]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTATTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAATTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

65.759

98.846

0.65
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504

Multiple sequence alignment