Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB2   Type   Machinery gene
Locus tag   COO52_RS00220 Genome accession   NZ_CP023448
Coordinates   33489..33770 (+) Length   93 a.a.
NCBI ID   WP_001272686.1    Uniprot ID   G2MDJ3
Organism   Helicobacter pylori strain HPJP26     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 28489..38770
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  COO52_RS00195 groES 29065..29421 (-) 357 WP_000671953.1 co-chaperone GroES -
  COO52_RS00205 dnaG 29696..31375 (+) 1680 WP_096478414.1 DNA primase -
  COO52_RS00210 - 31372..32424 (+) 1053 WP_096478415.1 MnmA/TRMU family protein -
  COO52_RS00215 - 32517..33344 (+) 828 WP_096478416.1 DUF5718 family protein -
  COO52_RS00220 comB2 33489..33770 (+) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  COO52_RS00225 comB3 33770..34033 (+) 264 WP_096478417.1 competence protein ComB Machinery gene
  COO52_RS00230 comB4 34035..36398 (+) 2364 WP_096478418.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  COO52_RS00240 - 36719..38059 (+) 1341 WP_212782414.1 COG3014 family protein -

Sequence

Protein


Download         Length: 93 a.a.        Molecular weight: 10539.81 Da        Isoelectric Point: 9.1450

>NTDB_id=247182 COO52_RS00220 WP_001272686.1 33489..33770(+) (comB2) [Helicobacter pylori strain HPJP26]
MSAHFLKIIFLVGMCVSSLFAEGLEGFFNALEAQLKSPIAKGILMVIFIGIAIYVWRNLDRWKEILFTILGVVFGIFLFF
KAPSLANWFMGIF

Nucleotide


Download         Length: 282 bp        

>NTDB_id=247182 COO52_RS00220 WP_001272686.1 33489..33770(+) (comB2) [Helicobacter pylori strain HPJP26]
ATGTCCGCTCATTTTTTAAAAATCATTTTTTTAGTAGGCATGTGCGTTTCAAGTTTGTTCGCTGAAGGTTTAGAGGGGTT
TTTTAACGCCCTAGAAGCCCAGCTCAAAAGCCCCATCGCTAAGGGGATTTTAATGGTGATTTTCATAGGGATCGCTATTT
ATGTGTGGAGGAATTTAGACCGGTGGAAAGAGATTTTATTCACGATCCTTGGCGTGGTGTTTGGGATTTTTTTATTCTTT
AAAGCCCCGAGTTTAGCGAATTGGTTCATGGGAATTTTTTAA

Domains

Predicted by InterproScan.

TrbC/VIRB2 pilin (TrbC)

(6-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G2MDJ3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB2 Helicobacter pylori 26695

98.925

100

0.989

Multiple sequence alignment