Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   TTH_RS08325 Genome accession   NC_006461
Coordinates   1559701..1561935 (-) Length   744 a.a.
NCBI ID   WP_011228829.1    Uniprot ID   Q76DY7
Organism   Thermus thermophilus HB8     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1554701..1566935
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TTH_RS08305 (TTHA1641) - 1555814..1556896 (+) 1083 WP_011228826.1 GGDEF domain-containing protein -
  TTH_RS08310 (TTHA1642) metK 1556998..1558176 (-) 1179 WP_038038694.1 methionine adenosyltransferase -
  TTH_RS08315 (TTHA1643) murI 1558271..1559044 (+) 774 WP_011228827.1 glutamate racemase -
  TTH_RS08320 (TTHA1644) - 1559073..1559726 (+) 654 WP_011228828.1 TIGR00730 family Rossman fold protein -
  TTH_RS08325 (TTHA1645) mutS/mutS2 1559701..1561935 (-) 2235 WP_011228829.1 endonuclease MutS2 Machinery gene
  TTH_RS08330 (TTHA1646) - 1561958..1562296 (-) 339 WP_024118727.1 hypothetical protein -
  TTH_RS08335 (TTHA1647) - 1562302..1564014 (-) 1713 WP_164926067.1 glycoside hydrolase family 13 protein -
  TTH_RS08340 (TTHA1648) - 1564011..1564157 (-) 147 WP_224065241.1 DUF86 domain-containing protein -
  TTH_RS08345 (TTHA1649) - 1564182..1564469 (-) 288 WP_011173685.1 nucleotidyltransferase family protein -
  TTH_RS08350 (TTHA1650) - 1564474..1565793 (-) 1320 WP_011228833.1 sugar ABC transporter permease -

Sequence

Protein


Download         Length: 744 a.a.        Molecular weight: 82516.51 Da        Isoelectric Point: 7.0037

>NTDB_id=24457 TTH_RS08325 WP_011228829.1 1559701..1561935(-) (mutS/mutS2) [Thermus thermophilus HB8]
MRDVLEVLEFPRVRALLAERAKTPLGRELALALAPLPREEAEKRHELTGEALSYPYALPEAGTLREAYGRALAGARLSGP
ELLKAAKALEEAMALKEELLPLKNALSQVAEGIGDHTPFLERVRKALDEEGAVKDEASPRLAQIRRELRPLRQQILDRLY
ALMDRHREAFQDRFVTLRRERYCVPVRAGMAQKVPGILLDESESGATLFIEPFSVVKLNNRLQALRLKEEEEVNRILRDL
SERLAKDEGVPKTLEALGLLDLVQAQAALARDLGLSRPAFGERYELYRAFHPLIPDAVRNSFALDEKNRILLISGPNMGG
KTALLKTLGLAVLMAQSGLFVAAEKALLAWPDRVYADIGDEQSLQENLSTFAGHLRRLREMLEEATSHSLVLIDELGSGT
DPEEGAALSQAILEALLERGVKGMVTTHLSPLKAFAQGREGIQNASMRFDLEALRPTYELVLGVPGRSYALAIARRLALP
EEVLKRAEALLPEGGRLEALLERLEAERLALEAERERLRRELSQVERLRKALAEREARFEEERAERLKALEEEVRAELLK
VEAELKALKEKARTEGKRDALRELMALRERYAKKAPPPPPPPGLAPGVLVEVPSLGKRGRVVELRGEEVLVQVGPLKMSL
KPQEVKPLPEAEPGKPLLAKPRREVKEVDLRGLTVAEALLEVDQALEEARALGLSTLRLLHGKGTGALRQAIREALRRDK
RVESFADAPPGEGGHGVTVVALRP

Nucleotide


Download         Length: 2235 bp        

>NTDB_id=24457 TTH_RS08325 WP_011228829.1 1559701..1561935(-) (mutS/mutS2) [Thermus thermophilus HB8]
GTGCGGGACGTCCTCGAGGTCCTGGAGTTCCCCCGGGTCCGGGCCCTGCTGGCGGAGAGGGCCAAGACCCCCCTGGGCCG
GGAGCTTGCCCTGGCCCTCGCGCCCCTTCCCCGGGAAGAGGCGGAGAAGCGGCACGAGCTCACGGGGGAGGCCCTAAGCT
ACCCCTACGCCCTCCCCGAGGCGGGGACCTTAAGGGAGGCCTACGGGAGGGCCCTCGCGGGGGCGAGGCTTTCCGGCCCC
GAGCTCCTAAAGGCGGCCAAGGCCCTGGAGGAGGCCATGGCCCTGAAGGAGGAGCTCCTTCCCCTGAAAAACGCCTTAAG
CCAGGTGGCGGAGGGCATCGGGGACCACACCCCCTTCCTGGAGCGGGTGAGGAAGGCCCTGGACGAGGAGGGGGCGGTGA
AGGACGAGGCGAGCCCGAGGCTTGCCCAGATCCGAAGGGAGCTTAGGCCCCTCCGCCAGCAGATCCTGGACCGCCTCTAC
GCCCTCATGGACCGCCACAGGGAGGCCTTCCAGGACCGCTTCGTCACCTTAAGGCGGGAGCGCTACTGCGTCCCCGTGAG
GGCGGGGATGGCCCAGAAGGTGCCGGGGATCCTCCTGGACGAGTCCGAGTCGGGGGCGACCCTCTTCATAGAGCCCTTCT
CCGTGGTCAAGCTCAACAACCGCCTCCAGGCCCTGAGGCTAAAGGAGGAGGAGGAGGTGAACCGCATCCTCCGGGACCTC
TCCGAGAGGCTCGCCAAGGACGAGGGGGTGCCGAAGACCCTGGAGGCCCTGGGCCTTTTGGACCTCGTCCAGGCCCAGGC
CGCCTTGGCCCGGGACCTGGGGCTTTCCCGCCCCGCTTTCGGGGAGCGGTACGAGCTCTACCGGGCCTTTCACCCCCTGA
TCCCGGACGCCGTGCGGAACTCCTTCGCCCTGGACGAGAAAAACCGCATCCTCCTCATCTCCGGTCCCAACATGGGGGGA
AAGACCGCCCTCCTCAAGACCCTGGGCCTCGCTGTCCTCATGGCCCAGTCCGGCCTCTTCGTGGCGGCGGAGAAGGCCCT
TTTGGCCTGGCCCGACCGGGTCTATGCCGACATCGGGGACGAGCAGTCCCTTCAGGAGAACCTCTCCACCTTCGCCGGGC
ACTTAAGGCGCCTCAGGGAGATGCTGGAGGAGGCCACCTCCCATAGCCTCGTCCTCATTGACGAGCTCGGAAGCGGCACC
GACCCCGAGGAGGGGGCGGCCCTTTCCCAGGCCATCCTGGAGGCCCTCCTGGAGAGGGGGGTCAAGGGGATGGTCACCAC
CCACCTCTCCCCCCTGAAGGCCTTCGCCCAGGGAAGGGAGGGGATCCAGAACGCCTCCATGCGCTTTGACCTCGAGGCCC
TCCGCCCCACCTACGAGCTCGTCCTCGGGGTGCCGGGGCGGAGCTACGCCTTGGCCATCGCGAGGAGGCTCGCCCTCCCC
GAGGAGGTCCTCAAGCGGGCCGAGGCCCTTCTGCCCGAGGGGGGGAGGCTGGAGGCCCTTCTGGAGAGGCTCGAGGCCGA
GCGCCTGGCCCTGGAGGCGGAGCGGGAGCGCCTGAGGCGGGAGCTTTCCCAGGTGGAGAGGCTGCGCAAGGCCCTGGCCG
AGCGGGAGGCCCGCTTTGAGGAGGAGCGGGCGGAAAGGCTCAAGGCCCTCGAGGAGGAGGTGCGGGCCGAGCTCCTCAAG
GTGGAGGCCGAGCTCAAGGCCCTCAAGGAGAAGGCCCGGACCGAGGGCAAGCGGGACGCCCTCCGGGAGCTCATGGCCCT
CCGGGAGCGCTACGCCAAGAAGGCCCCGCCGCCCCCGCCTCCCCCGGGCCTCGCCCCCGGGGTCTTGGTGGAGGTGCCCT
CCTTGGGCAAACGGGGCCGGGTGGTGGAGCTCAGGGGGGAGGAGGTCCTGGTCCAGGTGGGCCCCCTGAAGATGAGCCTC
AAGCCCCAGGAGGTGAAGCCCCTTCCCGAGGCCGAACCGGGCAAGCCCCTCCTCGCCAAGCCCCGACGGGAGGTGAAGGA
GGTGGACCTCCGGGGCCTCACGGTGGCCGAGGCCCTCCTGGAGGTGGACCAGGCCCTGGAGGAGGCGCGGGCCCTGGGCC
TTTCCACCCTCCGCCTCCTCCACGGCAAGGGGACGGGGGCCTTAAGGCAGGCCATCCGGGAGGCCCTCCGCCGGGACAAG
CGGGTGGAAAGCTTCGCCGACGCCCCGCCCGGCGAGGGGGGGCATGGGGTTACCGTGGTGGCGCTTCGGCCTTGA

Domains

Predicted by InterProScan.

MutS2 and Smr-associated SH3 domain (MSSS)

(606-644)

MutS domain V (MutS_V)

(312-490)

Smr domain (Smr)

(668-743)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q76DY7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

34.799

100

0.372

Multiple sequence alignment