Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   Sp14A_RS07155 Genome accession   NZ_CP022601
Coordinates   1388882..1389763 (-) Length   293 a.a.
NCBI ID   WP_115130480.1    Uniprot ID   A0A345VKZ6
Organism   Streptococcus pluranimalium strain 14A0014     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1383882..1394763
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Sp14A_RS07135 (Sp14A_14820) pheT 1384285..1386690 (-) 2406 WP_115130476.1 phenylalanine--tRNA ligase subunit beta -
  Sp14A_RS07140 (Sp14A_14830) - 1386882..1387409 (-) 528 WP_115130477.1 N-acetyltransferase -
  Sp14A_RS07145 (Sp14A_14840) pheS 1387421..1388464 (-) 1044 WP_115130478.1 phenylalanine--tRNA ligase subunit alpha -
  Sp14A_RS07155 (Sp14A_14850) endA 1388882..1389763 (-) 882 WP_115130480.1 DNA/RNA non-specific endonuclease Machinery gene
  Sp14A_RS07160 (Sp14A_14860) - 1389797..1389985 (-) 189 WP_115130481.1 DNA-directed RNA polymerase subunit beta -
  Sp14A_RS07165 (Sp14A_14870) murA 1389987..1391255 (-) 1269 WP_115130482.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  Sp14A_RS07170 (Sp14A_14880) - 1391296..1391532 (-) 237 WP_115130483.1 DUF1146 family protein -
  Sp14A_RS07180 (Sp14A_14890) - 1391983..1392399 (-) 417 WP_115130485.1 F0F1 ATP synthase subunit epsilon -
  Sp14A_RS07185 (Sp14A_14900) atpD 1392412..1393818 (-) 1407 WP_115130486.1 F0F1 ATP synthase subunit beta -

Sequence

Protein


Download         Length: 293 a.a.        Molecular weight: 31950.43 Da        Isoelectric Point: 9.0218

>NTDB_id=241056 Sp14A_RS07155 WP_115130480.1 1388882..1389763(-) (endA) [Streptococcus pluranimalium strain 14A0014]
MVKPYDVKKSSKSKFSVLVVIITLILGLVAGTDQLSDDNPLKQLAQVVTNGSNQEKVNSNGSSANESTPNQDLAQSVLTS
SVRKSLGDDIKWNGAGAFVINNNKTNLDASVSSMPYVDNKIKRVQGKLVPSVANAMLSKHSRQYRNRELTGNGSTSWKPA
GWHQVHDLPGEYDHAIDRGHLIGYAIAGNIDGFDPSASNPQNIAVQTAWSNQARDHDSTGQNYYETQIRRALDNNKRVRY
RVTLVYEGDNIIASGSHLESKSSDGSLEFNVFVPNVQPGITLNYANGQVTVNH

Nucleotide


Download         Length: 882 bp        

>NTDB_id=241056 Sp14A_RS07155 WP_115130480.1 1388882..1389763(-) (endA) [Streptococcus pluranimalium strain 14A0014]
ATGGTTAAACCTTATGATGTAAAAAAATCATCTAAATCGAAGTTTTCTGTTCTAGTAGTCATTATAACCTTAATCTTAGG
TCTTGTTGCAGGGACAGATCAGCTGTCAGATGATAACCCTCTGAAACAGCTAGCTCAAGTTGTGACGAATGGTTCAAATC
AGGAAAAAGTAAATTCTAACGGCTCAAGTGCAAATGAATCGACACCAAACCAAGACTTAGCGCAATCTGTTTTGACCTCA
TCTGTTAGAAAATCTTTAGGAGATGATATCAAATGGAATGGTGCAGGTGCCTTTGTGATTAATAACAACAAAACAAATCT
TGATGCCAGTGTGTCCAGCATGCCTTATGTGGATAATAAAATAAAGCGGGTCCAAGGAAAGCTTGTCCCGTCAGTAGCAA
ATGCTATGCTGTCTAAACATAGTCGACAATATCGTAACCGTGAATTAACGGGAAATGGGTCAACGTCATGGAAGCCGGCA
GGCTGGCATCAGGTTCATGATTTACCAGGTGAATACGATCATGCTATTGATCGAGGTCACTTAATTGGTTACGCCATTGC
GGGTAATATTGATGGCTTTGACCCTTCTGCAAGTAACCCTCAAAATATCGCTGTTCAGACAGCTTGGTCTAACCAAGCTA
GAGATCATGATTCAACGGGGCAAAACTATTATGAGACACAAATTCGTCGTGCTTTAGATAATAATAAACGTGTTCGTTAT
CGTGTGACTCTTGTTTATGAAGGCGATAATATCATTGCTTCTGGCTCGCATCTTGAATCCAAATCAAGTGATGGTAGTTT
GGAATTTAATGTCTTTGTACCAAATGTTCAACCTGGCATTACGCTTAACTATGCTAATGGGCAGGTGACAGTTAATCATT
AA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(96-251)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A345VKZ6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

59.917

82.594

0.495
  endA Streptococcus pneumoniae D39

59.917

82.594

0.495
  endA Streptococcus pneumoniae R6

59.917

82.594

0.495
  endA Streptococcus pneumoniae TIGR4

59.917

82.594

0.495

Multiple sequence alignment