Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   TTH_RS01425 Genome accession   NC_006461
Coordinates   255678..256745 (-) Length   355 a.a.
NCBI ID   WP_011227821.1    Uniprot ID   Q5SLM4
Organism   Thermus thermophilus HB8     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 250678..261745
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TTH_RS01400 (TTHA0264) recF 251698..252729 (+) 1032 WP_011227816.1 DNA replication/repair protein RecF -
  TTH_RS01405 (TTHA0265) - 252714..253472 (+) 759 WP_165446277.1 DUF721 domain-containing protein -
  TTH_RS01410 (TTHA0266) - 253473..254249 (+) 777 WP_011227818.1 C40 family peptidase -
  TTH_RS01415 (TTHA0267) - 254203..255123 (-) 921 WP_011227819.1 nitroreductase family protein -
  TTH_RS01420 (TTHA0268) - 255137..255640 (-) 504 WP_011227820.1 DUF2939 domain-containing protein -
  TTH_RS01425 (TTHA0269) pilD 255678..256745 (-) 1068 WP_011227821.1 A24 family peptidase Machinery gene
  TTH_RS01430 (TTHA0270) - 256812..258344 (+) 1533 WP_011174078.1 thermostable carboxypeptidase 1 -
  TTH_RS01435 (TTHA0271) groL 258408..260039 (-) 1632 WP_011174077.1 chaperonin GroEL -
  TTH_RS01440 (TTHA0272) groES 260052..260357 (-) 306 WP_011174076.1 co-chaperone GroES -
  TTH_RS01445 (TTHA0273) - 260454..261101 (-) 648 WP_224065233.1 transposase -
  TTH_RS11430 - 261043..261228 (+) 186 WP_223966770.1 hypothetical protein -

Sequence

Protein


Download         Length: 355 a.a.        Molecular weight: 37888.18 Da        Isoelectric Point: 8.1123

>NTDB_id=23999 TTH_RS01425 WP_011227821.1 255678..256745(-) (pilD) [Thermus thermophilus HB8]
MWPLFALLLGLAVGSFLNVVVHRLPRGESVAYPPSRCPQCGHRLGPWDLVPVLSYLALKGRCRYCARPISPRYPLVEALT
GGLFLLASLFYPPGVEALLVFLFLAFLVALAFIDVDTFELPDPLTYGLLFLGLLASWALAFPLPFRESLDGSLMAAGGLA
LVAGYGNLFLRRFREARAEVPVGPHQVHMAALFGALLGPGVGMALAFLAWALSARTGRAVALPDRLTLPLLPLAFLLAPA
LGLDFLESLKGSLLAAGGLALAGGLYWAFRPLPEEGEEEPVAMGYGDVKLLGALGAWLGPYAFLALFLGVFAGALLGLLL
RQRKLPFGPYLALGGVVAFFFGEALWGAYLRLLGV

Nucleotide


Download         Length: 1068 bp        

>NTDB_id=23999 TTH_RS01425 WP_011227821.1 255678..256745(-) (pilD) [Thermus thermophilus HB8]
ATGTGGCCCCTCTTCGCCCTGCTCCTCGGCCTCGCGGTGGGTTCCTTTCTCAACGTGGTGGTCCACCGCCTGCCCCGGGG
GGAGTCCGTCGCCTACCCCCCGTCCCGCTGCCCCCAGTGCGGCCACCGCCTGGGGCCTTGGGACCTGGTCCCCGTCCTCT
CCTACCTCGCCCTAAAGGGGCGGTGCCGCTACTGCGCCCGTCCCATCTCCCCCCGCTACCCCCTGGTGGAGGCCCTCACG
GGGGGGCTTTTCCTCCTCGCAAGCCTCTTCTACCCCCCTGGGGTGGAGGCCCTCTTGGTCTTCCTCTTCCTCGCCTTTCT
CGTGGCCCTCGCCTTCATTGACGTGGACACCTTTGAGCTTCCCGATCCCCTCACCTACGGCCTCCTCTTCCTTGGGCTTT
TGGCCTCCTGGGCGCTGGCCTTCCCCCTCCCCTTTAGGGAGAGCCTGGACGGAAGCCTCATGGCCGCCGGGGGGCTCGCC
CTGGTGGCGGGGTACGGGAACCTCTTTCTGCGGCGCTTTAGGGAGGCCAGGGCCGAGGTCCCCGTGGGGCCCCACCAGGT
CCACATGGCGGCCCTCTTTGGGGCGCTCTTGGGCCCAGGGGTGGGGATGGCCCTCGCCTTCCTCGCTTGGGCCCTCTCCG
CCCGCACGGGGCGGGCGGTGGCCCTCCCCGACCGGCTCACCCTGCCCCTTTTGCCCCTCGCCTTCCTCCTTGCCCCCGCC
CTAGGCCTGGACTTCCTGGAAAGCCTTAAGGGAAGCCTCCTCGCTGCCGGGGGGCTCGCCCTCGCCGGGGGGCTTTACTG
GGCCTTCCGGCCCCTTCCCGAGGAGGGCGAGGAGGAGCCCGTGGCCATGGGCTACGGGGACGTGAAGCTTCTGGGGGCCC
TCGGGGCCTGGCTCGGCCCTTACGCCTTCCTCGCCCTCTTCCTCGGGGTCTTCGCCGGGGCGCTTTTGGGCCTTCTCCTT
AGGCAAAGGAAGCTCCCCTTCGGCCCCTACCTCGCCCTCGGGGGGGTGGTGGCCTTCTTCTTCGGGGAGGCCCTCTGGGG
GGCGTACCTGCGCCTTCTGGGCGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-88)

Type IV leader peptidase family (Peptidase_A24)

(207-318)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5SLM4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

44.909

100

0.485

Multiple sequence alignment