Detailed information NTG0238992

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: QMA0248_RS05760
• Genome accession: NZ_CP022392
• Coordinates: 1182410..1183273 (-)
• Length: 287 a.a.
• NCBI ID: WP_003099993.1
• Uniprot ID: A0A3L8GIC3
• Organism: Streptococcus iniae strain QMA0248
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1177410..1188273

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QMA0248_RS05740 (QMA0248_1163)	-	1177664..1178044 (-)	381	WP_003099988.1	OsmC family protein	-
QMA0248_RS05745 (QMA0248_1164)	pheT	1178117..1180522 (-)	2406	WP_003099989.1	phenylalanine--tRNA ligase subunit beta	-
QMA0248_RS05750 (QMA0248_1165)	-	1180538..1181062 (-)	525	WP_003099991.1	GNAT family N-acetyltransferase	-
QMA0248_RS05755 (QMA0248_1166)	pheS	1181075..1182118 (-)	1044	WP_003099992.1	phenylalanine--tRNA ligase subunit alpha	-
QMA0248_RS05760 (QMA0248_1167)	endA	1182410..1183273 (-)	864	WP_003099993.1	DNA/RNA non-specific endonuclease	Machinery gene
QMA0248_RS05765 (QMA0248_1168)	-	1183304..1183492 (-)	189	WP_003099995.1	DNA-directed RNA polymerase subunit beta	-
QMA0248_RS05770 (QMA0248_1169)	murA	1183496..1184767 (-)	1272	WP_003099997.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
QMA0248_RS05775 (QMA0248_2094)	-	1184833..1185069 (-)	237	WP_071794729.1	DUF1146 family protein	-
QMA0248_RS05780 (QMA0248_1170)	-	1185145..1185561 (-)	417	WP_003100001.1	F0F1 ATP synthase subunit epsilon	-
QMA0248_RS05785 (QMA0248_1171)	atpD	1185574..1186980 (-)	1407	WP_003100002.1	F0F1 ATP synthase subunit beta	-
QMA0248_RS05790 (QMA0248_1172)	-	1187096..1187971 (-)	876	WP_003100004.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 287 a.a.
• Molecular weight: 31715.35 Da
• Isoelectric Point: 9.3865

>NTDB_id=238992 QMA0248_RS05760 WP_003099993.1 1182410..1183273(-) (endA) [Streptococcus iniae strain QMA0248]
MSPKTKQSQKINLLLFLLVLVGLFYLIDSKEGEENNPIRAFYQSVMGASNQTSQKESSNPDTPSYALASSVLTEKVKRQL
GSKVEWNGNGAFVINDNSTNLDAKVSSAPYAHNQTRLLSGKKLPTVANALLAKSTRQYRDRNETGNGYSYWKPAGWHQIH
GLSGKYDHAVDRGHLLGYALVGGLKGFDASTSNSDNIATQLSWANQAMDSDSTGQNYYETKIRRALDKNKRVRYRVTLIY
EADNILASGSHLEAKSDDGSLEFNVFVPNVQKGLEVDYQTGQITVSH

Nucleotide

• Length: 864 bp

>NTDB_id=238992 QMA0248_RS05760 WP_003099993.1 1182410..1183273(-) (endA) [Streptococcus iniae strain QMA0248]
ATGTCACCAAAGACAAAACAAAGTCAAAAAATCAATCTATTATTGTTTCTGCTTGTGCTCGTTGGCTTATTCTATTTGAT
TGATAGTAAAGAAGGGGAAGAGAATAATCCTATTCGAGCCTTTTATCAATCAGTGATGGGAGCTTCCAATCAAACTAGCC
AAAAAGAATCAAGCAATCCTGATACACCAAGTTATGCCTTGGCATCTTCGGTTTTAACAGAAAAAGTAAAAAGACAACTT
GGTTCGAAAGTTGAGTGGAATGGTAATGGTGCATTTGTCATCAATGATAACAGTACCAATTTGGATGCAAAAGTATCCAG
TGCTCCCTATGCTCACAATCAAACCAGACTCTTATCAGGGAAAAAGCTTCCAACAGTCGCCAATGCTTTACTTGCCAAAT
CAACAAGGCAATACCGAGACCGAAACGAGACCGGAAATGGCTACTCTTATTGGAAACCTGCTGGTTGGCACCAGATTCAT
GGTTTATCAGGAAAATATGATCACGCTGTGGACCGTGGGCATTTATTAGGCTATGCTTTAGTGGGAGGTCTTAAAGGATT
TGATGCCTCTACAAGCAATAGCGATAACATAGCAACGCAATTATCCTGGGCTAACCAAGCGATGGATAGTGATTCCACTG
GCCAAAATTATTATGAAACAAAAATCAGACGTGCATTGGACAAGAATAAGCGTGTCCGTTACCGTGTTACCCTCATTTAC
GAGGCTGATAATATATTAGCAAGTGGAAGCCATTTAGAAGCAAAATCAGATGACGGCAGTTTAGAATTTAACGTTTTTGT
GCCAAATGTTCAAAAAGGTCTAGAAGTTGACTATCAAACAGGACAAATAACAGTCAGTCACTAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (95-245)

3D structure

• AlphaFold DB: A0A3L8GIC3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	63.559	82.23	0.523
endA	Streptococcus pneumoniae D39	63.559	82.23	0.523
endA	Streptococcus pneumoniae R6	63.559	82.23	0.523
endA	Streptococcus pneumoniae TIGR4	63.559	82.23	0.523