Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   M6_RS10090 Genome accession   NC_006086
Coordinates   600029..600895 (+) Length   288 a.a.
NCBI ID   WP_011184363.1    Uniprot ID   -
Organism   Streptococcus pyogenes MGAS10394     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 595029..605895
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M6_RS03085 (M6_Spy0597) - 595070..595945 (+) 876 WP_002985236.1 F0F1 ATP synthase subunit gamma -
  M6_RS03090 (M6_Spy0598) atpD 596107..597513 (+) 1407 WP_011017611.1 F0F1 ATP synthase subunit beta -
  M6_RS03095 (M6_Spy0599) - 597526..597942 (+) 417 WP_002985233.1 F0F1 ATP synthase subunit epsilon -
  M6_RS03100 (M6_Spy0600) - 598229..598465 (+) 237 WP_280529076.1 DUF1146 family protein -
  M6_RS03105 (M6_Spy0601) murA 598530..599801 (+) 1272 WP_002994428.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  M6_RS03110 (M6_Spy0602) - 599805..599993 (+) 189 WP_011017613.1 DNA-directed RNA polymerase subunit beta -
  M6_RS10090 (M6_Spy0603) endA 600029..600895 (+) 867 WP_011184363.1 DNA/RNA non-specific endonuclease Machinery gene
  M6_RS03120 (M6_Spy0604) pheS 601178..602221 (+) 1044 WP_003057440.1 phenylalanine--tRNA ligase subunit alpha -
  M6_RS03125 (M6_Spy0605) pheT 602431..604836 (+) 2406 WP_023078221.1 phenylalanine--tRNA ligase subunit beta -
  M6_RS03130 (M6_Spy0606) - 604948..605325 (+) 378 WP_021340346.1 OsmC family protein -
  M6_RS03135 (M6_Spy0607) - 605318..605704 (+) 387 WP_002990406.1 YbgA family protein -

Sequence

Protein


Download         Length: 288 a.a.        Molecular weight: 32111.62 Da        Isoelectric Point: 10.4010

>NTDB_id=23838 M6_RS10090 WP_011184363.1 600029..600895(+) (endA) [Streptococcus pyogenes MGAS10394]
MLAKKKRKRVLNSFLLILLVLGSNCLAKSDFIASNHPIKQLYQTLVGEKKKSLLTHNNLPADVPTEALAASVLTPSIKKQ
LGPDVQWNGAGAYIINRNKTDLNAKVASLPYANNETKWVQEQKVPKRANALLTKSTRQYRNRYQTDNAYRNFKPAGWHRL
HRLKGSYDHAVDRGHLLGYALVGGLKGLDASTGNPDNIATQLSWANQANKPYSTGQNYYEGLVCRALDKGHRVRYRVTLL
YDGDNLLASGSHLEAKSSDDSLTFNVFVPNVQPGLTVDYRTRQIAINL

Nucleotide


Download         Length: 867 bp        

>NTDB_id=23838 M6_RS10090 WP_011184363.1 600029..600895(+) (endA) [Streptococcus pyogenes MGAS10394]
ATGTTAGCAAAGAAAAAACGAAAAAGGGTGCTTAATTCCTTCTTATTGATTTTGTTAGTGTTGGGGTCTAACTGCCTTGC
TAAGAGTGATTTCATAGCTAGCAATCACCCTATCAAGCAACTTTATCAGACTCTTGTTGGGGAGAAGAAAAAATCATTAC
TCACACATAATAATTTGCCCGCTGATGTTCCCACAGAAGCTCTGGCGGCATCGGTATTAACACCATCAATCAAAAAGCAA
CTAGGTCCAGATGTTCAGTGGAATGGAGCAGGCGCCTATATTATCAACAGGAACAAAACAGATTTAAATGCTAAGGTAGC
CAGTCTGCCCTATGCCAACAATGAAACCAAATGGGTGCAAGAGCAAAAGGTTCCTAAAAGAGCTAATGCCTTACTTACTA
AGTCGACACGACAGTATCGAAATCGCTATCAAACGGACAATGCTTATCGTAACTTTAAGCCAGCAGGTTGGCACCGATTG
CACCGCTTAAAAGGAAGTTATGATCACGCGGTTGATAGAGGGCATTTGCTAGGTTATGCTTTAGTTGGTGGACTGAAAGG
TTTAGATGCTTCTACCGGTAATCCTGATAATATTGCCACTCAACTAAGTTGGGCTAATCAAGCAAATAAACCCTACTCGA
CAGGTCAGAATTACTATGAAGGTTTAGTATGTCGTGCTTTGGATAAGGGGCATCGCGTCCGCTACCGTGTCACCCTACTT
TATGATGGTGATAATCTACTAGCCAGCGGTAGCCATTTGGAGGCTAAATCCTCTGATGACAGCTTGACTTTTAACGTGTT
TGTTCCAAATGTCCAACCAGGATTGACCGTTGACTATAGGACGAGACAAATAGCTATCAATCTCTAA

Domains

Predicted by InterProScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(111-246)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

57.806

82.292

0.476
  endA Streptococcus pneumoniae D39

57.806

82.292

0.476
  endA Streptococcus pneumoniae R6

57.806

82.292

0.476
  endA Streptococcus pneumoniae TIGR4

57.806

82.292

0.476

Multiple sequence alignment