Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   C7K40_RS02335 Genome accession   NZ_CP027771
Coordinates   430073..430855 (+) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain DMG1800716     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 425073..435855
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7K40_RS02315 (C7K40_02315) - 425410..426375 (-) 966 WP_011054948.1 asparaginase -
  C7K40_RS02320 (C7K40_02320) - 426447..427835 (+) 1389 WP_009881044.1 Cof-type HAD-IIB family hydrolase -
  C7K40_RS02325 (C7K40_02325) - 427958..428410 (-) 453 WP_002992571.1 universal stress protein -
  C7K40_RS02330 (C7K40_02330) - 428641..429855 (+) 1215 WP_063629685.1 pyridoxal phosphate-dependent aminotransferase -
  C7K40_RS02335 (C7K40_02335) codY 430073..430855 (+) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  C7K40_RS02340 (C7K40_02340) - 431002..431556 (+) 555 WP_002992568.1 isochorismatase family cysteine hydrolase -
  C7K40_RS02350 (C7K40_02350) - 432095..432319 (+) 225 WP_227874710.1 putative PEP-binding protein -
  C7K40_RS02355 (C7K40_02355) gatC 432551..432853 (+) 303 WP_012560907.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  C7K40_RS02360 (C7K40_02360) gatA 432853..434319 (+) 1467 WP_011528911.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  C7K40_RS02365 (C7K40_02365) gatB 434319..435758 (+) 1440 WP_023613254.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=237172 C7K40_RS02335 WP_002983278.1 430073..430855(+) (codY) [Streptococcus pyogenes strain DMG1800716]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=237172 C7K40_RS02335 WP_002983278.1 430073..430855(+) (codY) [Streptococcus pyogenes strain DMG1800716]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAATTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504