Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   TT_RS06470 Genome accession   NC_005835
Coordinates   1235685..1237919 (-) Length   744 a.a.
NCBI ID   WP_011173682.1    Uniprot ID   Q72I50
Organism   Thermus thermophilus HB27     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1230685..1242919
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TT_RS06450 (TT_C1278) - 1231797..1232879 (+) 1083 WP_011173678.1 GGDEF domain-containing protein -
  TT_RS06455 (TT_C1279) metK 1232981..1234159 (-) 1179 WP_038038694.1 methionine adenosyltransferase -
  TT_RS06460 (TT_C1280) murI 1234254..1235027 (+) 774 WP_011173680.1 glutamate racemase -
  TT_RS06465 (TT_C1281) - 1235057..1235710 (+) 654 WP_011173681.1 TIGR00730 family Rossman fold protein -
  TT_RS06470 (TT_C1282) mutS/mutS2 1235685..1237919 (-) 2235 WP_011173682.1 endonuclease MutS2 Machinery gene
  TT_RS06475 (TT_C1283) - 1238011..1239723 (-) 1713 WP_011173683.1 glycoside hydrolase family 13 protein -
  TT_RS06480 (TT_C1284) - 1239720..1240055 (-) 336 WP_011173684.1 HepT-like ribonuclease domain-containing protein -
  TT_RS06485 (TT_C1285) - 1240052..1240339 (-) 288 WP_011173685.1 nucleotidyltransferase family protein -
  TT_RS06490 (TT_C1286) - 1240344..1241663 (-) 1320 WP_011173686.1 sugar ABC transporter permease -

Sequence

Protein


Download         Length: 744 a.a.        Molecular weight: 82501.50 Da        Isoelectric Point: 6.9483

>NTDB_id=23672 TT_RS06470 WP_011173682.1 1235685..1237919(-) (mutS/mutS2) [Thermus thermophilus HB27]
MRDVLEVLEFPRVRALLAERAKTPLGRELALALAPLPREEAEKRHELTGEALSYPYALPEAGALREAYGRALAGARLSGP
ELLKAAKALEEAMALKEELLPLKNALSQVAEGIGDHTPFLERVRKALDEEGAVKDEASPRLAQIRRELRPLRQQILDRLY
ALMDRHREAFQDRFVTLRRERYCVPVRAGMAQKVPGILLDESESGATLFIEPFSVVKLNNRLQALRLKEEEEVNRILRDL
SERLAKDEGVPKTLEALGLLDLVQAQAALARDLGLSRPAFGERYELYRAFHPLIPDAVRNSFALDEKNRILLISGPNMGG
KTALLKTLGLAVLMAQSGLFVAAEKALLAWPDRVYADIGDEQSLQENLSTFAGHLRRLKEMLEEATPTSLVLIDELGSGT
DPEEGAALSQAILEALLERGVKGMVTTHLSPLKAFAQGREGIQNASMRFDLEALRPTYELVLGVPGRSYALAIARRLALP
EEVLKRAEALLPEGGRLEALLERLEAERLALEAERERLRRELSQVERLRKALAEREARFEEERAERLKALEEEVRAELLK
VEAELKALKEKARNEGKRDALRELMALRERYAKKAPPPPPPPGLAPGVLVEVPSLGKRGRVVELRGEEVLVQVGPLRMSL
RPQEVKPLPEAEPGKPLLAKPRREVKEVDLRGLTVAEALLEVDQALEEARALGLSTLRLLHGKGTGALRQAIREALRRDK
RVESFADAPPGEGGHGVTVVALRP

Nucleotide


Download         Length: 2235 bp        

>NTDB_id=23672 TT_RS06470 WP_011173682.1 1235685..1237919(-) (mutS/mutS2) [Thermus thermophilus HB27]
GTGCGGGACGTCCTCGAGGTCCTGGAGTTCCCCCGGGTCCGGGCCCTGCTGGCGGAGAGGGCCAAGACCCCCCTGGGCCG
GGAGCTTGCCCTGGCCCTCGCGCCCCTTCCCCGGGAAGAGGCGGAGAAGCGGCACGAGCTCACGGGGGAGGCCCTAAGCT
ACCCCTACGCCCTCCCCGAGGCGGGGGCCTTAAGGGAGGCCTACGGGAGGGCCCTCGCGGGGGCGAGGCTTTCCGGCCCC
GAGCTCCTAAAGGCGGCCAAGGCCCTGGAGGAGGCCATGGCCCTGAAGGAGGAGCTCCTTCCCCTGAAAAACGCCTTAAG
CCAGGTGGCGGAGGGCATCGGGGACCACACCCCCTTCCTGGAGCGGGTGAGGAAGGCCCTGGACGAGGAGGGGGCGGTGA
AGGACGAGGCGAGCCCGAGGCTTGCCCAGATCCGAAGGGAGCTTAGGCCCCTCCGCCAGCAGATCCTGGACCGCCTCTAC
GCCCTCATGGACCGCCACAGGGAGGCCTTCCAGGACCGCTTCGTCACCTTAAGGCGGGAGCGCTACTGCGTCCCCGTGAG
GGCGGGGATGGCCCAGAAGGTGCCGGGGATCCTCCTGGACGAGTCCGAGTCGGGGGCGACCCTCTTCATAGAGCCCTTCT
CCGTGGTCAAGCTCAACAACCGCCTCCAGGCCCTGAGGCTAAAGGAGGAGGAGGAGGTGAACCGCATCCTCCGGGACCTC
TCCGAGAGGCTCGCCAAGGACGAGGGGGTGCCGAAGACCCTGGAGGCCCTGGGCCTTTTGGACCTCGTCCAGGCCCAGGC
CGCCTTGGCCCGGGACCTGGGGCTTTCCCGCCCCGCTTTCGGGGAGCGGTACGAGCTCTACCGGGCCTTTCACCCCCTGA
TCCCGGACGCCGTGCGGAACTCCTTCGCCCTGGACGAGAAAAACCGCATCCTCCTCATCTCCGGTCCCAACATGGGGGGA
AAGACCGCCCTCCTCAAGACCCTGGGCCTCGCCGTCCTCATGGCCCAGTCCGGCCTCTTCGTGGCGGCGGAGAAGGCCCT
TTTGGCCTGGCCCGACCGGGTCTATGCCGACATCGGGGACGAGCAGTCCCTTCAGGAGAACCTCTCCACCTTCGCCGGGC
ACTTAAGGCGCCTCAAGGAGATGCTGGAGGAGGCCACTCCCACGAGCCTCGTCCTCATTGACGAGCTCGGAAGCGGCACC
GACCCCGAGGAGGGGGCGGCCCTTTCCCAGGCCATCCTGGAGGCCCTCCTGGAGAGGGGGGTCAAGGGGATGGTCACCAC
CCACCTCTCCCCCCTGAAGGCCTTCGCCCAGGGAAGGGAGGGGATCCAGAACGCCTCCATGCGCTTTGACCTCGAGGCCC
TCCGTCCCACCTACGAGCTCGTCCTCGGGGTGCCGGGGCGGAGTTACGCCTTGGCCATCGCGAGGAGGCTCGCCCTCCCT
GAGGAGGTCCTCAAGCGGGCCGAGGCCCTTCTGCCCGAGGGGGGGCGGCTGGAGGCCCTTCTGGAGAGGCTCGAGGCCGA
GCGCCTGGCCCTGGAGGCGGAGCGGGAGCGCCTGAGGCGGGAGCTTTCCCAGGTGGAGAGGCTGCGCAAGGCCTTGGCCG
AGCGGGAGGCCCGCTTTGAGGAGGAGCGGGCGGAAAGGCTCAAGGCCCTCGAGGAGGAGGTGCGGGCCGAGCTCCTCAAG
GTGGAGGCCGAGCTCAAGGCCCTCAAGGAGAAGGCCAGGAACGAGGGCAAGCGGGACGCCCTCCGGGAACTCATGGCCCT
CCGGGAGCGCTACGCCAAGAAGGCCCCGCCGCCCCCGCCTCCGCCGGGCCTCGCCCCCGGGGTCTTGGTGGAGGTGCCGT
CCTTGGGCAAACGGGGCCGGGTGGTGGAGCTCAGGGGGGAGGAGGTCCTGGTCCAGGTGGGCCCCCTGAGGATGAGCCTC
AGGCCCCAGGAGGTGAAGCCCCTTCCCGAGGCCGAACCGGGCAAGCCCCTCCTCGCCAAGCCCCGGCGGGAGGTGAAGGA
GGTGGACCTCCGGGGCCTCACGGTGGCCGAGGCCCTTCTGGAGGTGGACCAGGCCCTGGAGGAGGCGCGGGCCCTGGGCC
TTTCCACCCTCCGCCTCCTCCACGGCAAGGGGACGGGGGCCTTAAGGCAGGCCATCCGGGAGGCCCTTCGCCGGGACAAG
CGGGTGGAAAGCTTCGCCGACGCCCCGCCCGGCGAGGGGGGGCATGGGGTTACCGTGGTGGCGCTTCGGCCTTGA

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(312-490)

Smr domain (Smr)

(668-743)

MutS2 and Smr-associated SH3 domain (MSSS)

(606-640)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q72I50

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

34.919

100

0.375