Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilH   Type   Machinery gene
Locus tag   CCD86_RS03060 Genome accession   NZ_CP021518
Coordinates   529828..530496 (+) Length   222 a.a.
NCBI ID   WP_002259882.1    Uniprot ID   -
Organism   Neisseria meningitidis strain 12-176     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 524828..535496
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCD86_RS03035 (CCD86_03050) - 525680..526012 (+) 333 WP_002229316.1 hypothetical protein -
  CCD86_RS03040 (CCD86_03055) - 526344..526853 (+) 510 WP_002213852.1 isoprenylcysteine carboxyl methyltransferase family protein -
  CCD86_RS03045 (CCD86_03060) - 527370..527957 (-) 588 WP_002222659.1 superoxide dismutase -
  CCD86_RS03055 (CCD86_03070) dnaB 528120..529526 (+) 1407 WP_002219448.1 replicative DNA helicase -
  CCD86_RS03060 (CCD86_03075) pilH 529828..530496 (+) 669 WP_002259882.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  CCD86_RS03065 (CCD86_03080) pilV 530526..531146 (+) 621 WP_002253554.1 type IV pilus modification protein PilV Machinery gene
  CCD86_RS03070 (CCD86_03085) pilJ 531143..532096 (+) 954 WP_002259883.1 PilW family protein Machinery gene
  CCD86_RS03075 (CCD86_03090) pilK 532075..532668 (+) 594 WP_002229321.1 PilX N-terminal domain-containing pilus assembly protein Machinery gene
  CCD86_RS03080 (CCD86_03095) pilX 532673..533146 (+) 474 WP_002229319.1 PilX family type IV pilin Machinery gene
  CCD86_RS03095 (CCD86_03110) - 534959..535387 (-) 429 Protein_528 AzlC family ABC transporter permease -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 24781.37 Da        Isoelectric Point: 9.9145

>NTDB_id=231581 CCD86_RS03060 WP_002259882.1 529828..530496(+) (pilH) [Neisseria meningitidis strain 12-176]
MCTRKQQGFTLTELLIVMVIAAIMAMIALPNMSQWIASRRIASHAERIANLLRFSRGEAVRLNLPVYICPVQVKKGGAPN
NKCDFGKKGQGMLAFGDKNGNKTYDGDTADVLLRSVVLNDDINDKRINYAFNHIAFGQTQPTADRVVWTFNQNGTFGYST
NQDLTNTSRFVYSDGYIQIVLTDARAVSDADKKFRSAVVLINSSGRVEVCPRNDRRTVCQYK

Nucleotide


Download         Length: 669 bp        

>NTDB_id=231581 CCD86_RS03060 WP_002259882.1 529828..530496(+) (pilH) [Neisseria meningitidis strain 12-176]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGTCATTGCAGCCATTATGGCGATGAT
AGCCCTCCCCAATATGAGCCAATGGATTGCATCCCGCCGCATTGCCAGTCATGCGGAGCGGATTGCCAACCTTTTGCGTT
TCTCCAGGGGAGAAGCCGTCCGGCTCAATCTTCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGGCGGTGCGCCCAAC
AATAAATGTGACTTCGGCAAGAAGGGGCAGGGAATGTTGGCTTTTGGCGATAAGAATGGCAATAAGACATATGACGGCGA
TACGGCGGATGTTCTCCTTCGCAGTGTGGTATTGAATGATGATATCAATGATAAGCGGATTAATTATGCCTTTAACCATA
TCGCTTTCGGTCAAACGCAGCCGACCGCTGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATTCTACC
AATCAGGATCTCACGAATACTTCCAGATTTGTTTACTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTAACAGCAGCGGCAGGGTTGAGGTTTGTCCTAGAAACG
ATAGGCGTACCGTATGCCAATATAAATGA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(4-29)

Type II transport protein GspH (GspH)

(44-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Neisseria gonorrhoeae MS11

85.068

99.55

0.847

Multiple sequence alignment