Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   SPYM3_RS08030 Genome accession   NC_004070
Coordinates   1533925..1534707 (-) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes MGAS315     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1528925..1539707
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYM3_RS08005 (SpyM3_1539) gatB 1529007..1530446 (-) 1440 WP_011054945.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  SPYM3_RS08010 (SpyM3_1540) gatA 1530446..1531912 (-) 1467 WP_011054946.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  SPYM3_RS08015 (SpyM3_1541) gatC 1531912..1532214 (-) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  SPYM3_RS08020 (SpyM3_1542) - 1532445..1532765 (-) 321 Protein_1556 putative PEP-binding protein -
  SPYM3_RS08025 (SpyM3_1543) - 1533224..1533778 (-) 555 WP_002992568.1 cysteine hydrolase family protein -
  SPYM3_RS08030 (SpyM3_1544) codY 1533925..1534707 (-) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  SPYM3_RS08035 (SpyM3_1545) - 1534925..1536139 (-) 1215 WP_010922605.1 pyridoxal phosphate-dependent aminotransferase -
  SPYM3_RS08040 (SpyM3_1546) - 1536370..1536822 (+) 453 WP_002992571.1 universal stress protein -
  SPYM3_RS08045 (SpyM3_1547) - 1536945..1538333 (-) 1389 WP_009881044.1 Cof-type HAD-IIB family hydrolase -
  SPYM3_RS08050 (SpyM3_1548) - 1538406..1539371 (+) 966 WP_011054948.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=22815 SPYM3_RS08030 WP_002983278.1 1533925..1534707(-) (codY) [Streptococcus pyogenes MGAS315]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=22815 SPYM3_RS08030 WP_002983278.1 1533925..1534707(-) (codY) [Streptococcus pyogenes MGAS315]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAATTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504